- Quantitative assessment of serum and urinary polyclonal free light chains in patients with type II diabetes: an early marker of diabetic kidney disease?
[作者:Hutchison, CA; Cockwell, P; Harding, S; Mead, GP; Bradwell, AR; Barnett, AH,期刊:Expert Opinion on Therapeutic Targets, 页码:667-676 , 文章类型: Article,,卷期:2008年12-6]
- Objective: Free light chains (FLCs) are bi-products of normal immunoglobulin synthesis and are predominately removed from the circulation by the kidneys. This study assessed polyclonal FLCs as a novel biomarker of early ...
- The paraventricular nucleus of the hypothalamus - a potential target for integrative treatment of autonomic dysfunction
[作者:Ferguson, AV; Latchford, KJ; Samson, WK,期刊:Expert Opinion on Therapeutic Targets, 页码:717-727 , 文章类型: Review,,卷期:2008年12-6]
- Background: The paraventricular nucleus of the hypothalamus (PVN) has emerged as one of the most important autonomic control centers in the brain, with neurons playing essential roles in controlling stress, metabolism, g...
- Src inhibitors in breast cancer therapy
[作者:Hiscox, S; Nicholson, RI,期刊:Expert Opinion on Therapeutic Targets, 页码:757-767 , 文章类型: Review,,卷期:2008年12-6]
- Background: Recent evidence has established the non receptor tyrosine kinase, Src, as a critical component of multiple signalling pathways that regulate proliferation, survival, angiogenesis and metastasis. Increased lev...
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