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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共49条记录   Clinical Features of Idiopathic Gastroparesis Vary With Sex, Body Mass, Symptom Onset, Delay in Gastric Emptying, and Gastroparesis Severity [作者：Parkman, HP; Yates, K; Hasler, WL; Nguyen, L; Pasricha, PJ; Snape, WJ; Farrugia, G; Koch, KL; Abell, TL; McCallum, RW; Lee, L; Unalp-Arida, A; Tonascia, J; Hamilton, F,期刊：Gastroenterology, 页码：101-+ , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Idiopathic gastroparesis (IG) is a common but poorly understood condition with significant morbidity. We studied characteristics of patients with IG enrolled in the National Institute of Diabetes and D... Histomorphometric Analysis Reveals Reduced Bone Mass and Bone Formation in Patients With Quiescent Crohn's Disease [作者：Oostlander, AE; Bravenboer, N; Sohl, E; Holzmann, PJ; van der Woude, CJ; Dijkstra, G; Stokkers, PCF; Oldenburg, B; Netelenbos, JC; Hommes, DW; van Bodegraven, AA; Lips, P,期刊：Gastroenterology, 页码：116-123 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Crohn's disease (CD) is associated with an increased prevalence of osteoporosis, but the pathogenesis of this bone loss is only partly understood. We assessed bone structure and remodeling at the tissu... Transient Receptor Potential Vanilloid 4 Activated Inflammatory Signals by Intestinal Epithelial Cells and Colitis in Mice [作者：D'Aldebert, E; Cenac, N; Rousset, P; Martin, L; Rolland, C; Chapman, K; Selves, J; Alric, L; Vinel, JP; Vergnolle, N,期刊：Gastroenterology, 页码：275-+ , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Ligand-gated calcium channels have been reported to be involved in the pathogenesis of inflammatory bowel disease. One family member, transient receptor potential vanilloid 4 (TRPV4), is activated by a... Sumoylation by Ubc9 Regulates the Stem Cell Compartment and Structure and Function of the Intestinal Epithelium in Mice [作者：Demarque, MD; Nacerddine, K; Neyret-Kahn, H; Andrieux, A; Danenberg, E; Jouvion, G; Bomme, P; Hamard, G; Romagnolo, B; Terris, B; Cumano, A; Barker, N; Clevers, H; Dejean, A,期刊：Gastroenterology, 页码：286-296 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Small ubiquitin-like modifiers (SUMOs) are attached to other proteins to regulate their function (sumoylation). We investigated the role of Ubc9, which covalently attaches SUMOs to proteins, in the gas... Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study [作者：Williams, CD; Stengel, J; Asike, MI; Torres, DM; Shaw, J; Contreras, M; Landt, CL; Harrison, SA,期刊：Gastroenterology, 页码：124-131 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Prevalence of nonalcoholic fatty liver disease (NAFLD) has not been well established. The purpose of this study was to prospectively define the prevalence of both NAFLD and nonalcoholic steatohepatitis... Three-Year Efficacy and Safety of Tenofovir Disoproxil Fumarate Treatment for Chronic Hepatitis B [作者：Heathcote, EJ; Marcellin, P; Buti, M; Gane, E; De Man, RA; Krastev, Z; Germanidis, G; Lee, SS; Flisiak, R; Kaita, K; Manns, M; Kotzev, I; Tchernev, K; Buggisch, P; Weilert, F; Kurdas, OO; Shiffman, ML; Trinh, H; Gurel, S; Snow-Lampart, A; Borroto-Esoda, K; Mondou, E; Anderson, J; Sorbel, J; Rousseau, F,期刊：Gastroenterology, 页码：132-143 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Tenofovir disoproxil fumarate (TDF), a nucleotide analogue and potent inhibitor of hepatitis B virus (HBV) polymerase, showed superior efficacy to adefovir dipivoxil in treatment of chronic hepatitis B... Bone Morphogenetic Protein 4 Induces Differentiation of Colorectal Cancer Stem Cells and Increases Their Response to Chemotherapy in Mice [作者：Lombardo, Y; Scopelliti, A; Cammareri, P; Todaro, M; Iovino, F; Ricci-Vitiani, L; Gulotta, G; Dieli, F; De Maria, R; Stassi, G,期刊：Gastroenterology, 页码：297-+ , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: The limited clinical response observed in many patients with colorectal cancer may be related to the presence of chemoresistant colorectal cancer stem cells (CRC-SCs). Bone morphogenetic protein 4 (BMP... CXCL17 and ICAM2 Are Associated With a Potential Anti-Tumor Immune Response in Early Intraepithelial Stages of Human Pancreatic Carcinogenesis [作者：Hiraoka, N; Yamazaki-Itoh, R; Ino, Y; Mizuguchi, Y; Yamada, T; Hirohashi, S; Kanai, Y,期刊：Gastroenterology, 页码：310-+ , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Anti-tumor immunity changes over the course of tumor progression; it is not clear how or when the developing tumor overcomes immune surveillance. Intraductal papillary mucinous neoplasm (IPMN) is an in... Statin Therapy Improves Sustained Virologic Response Among Diabetic Patients With Chronic Hepatitis C [作者：Rao, GA; Pandya, PK,期刊：Gastroenterology, 页码：144-+ , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Patients with chronic hepatitis C infection are 2- to 3-fold more likely to develop type 2 diabetes, which reduces their chances of achieving a sustained virologic response (SVR). To identify differenc... Type of CFTR Mutation Determines Risk of Pancreatitis in Patients With Cystic Fibrosis [作者：Ooi, CY; Dorfman, R; Cipolli, M; Gonska, T; Castellani, C; Keenan, K; Freedman, SD; Zielenski, J; Berthiaume, Y; Corey, M; Schibli, S; Tullis, E; Durie, PR,期刊：Gastroenterology, 页码：153-161 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Different mutations in the cystic fibrosis gene (CFTR) are associated with different functional status of the exocrine pancreas. We investigated whether CFTR genotypes determine the risk of pancreatiti... The MicroRNA miR-139 Suppresses Metastasis and Progression of Hepatocellular Carcinoma by Down-regulating Rho-Kinase 2 [作者：Wong, CCL; Wong, CM; Tung, EKK; Au, SLK; Lee, JMF; Poon, RTP; Man, K; Ng, IOL,期刊：Gastroenterology, 页码：322-331 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: We investigated mechanisms of hepatocellular carcinoma (HCC) metastasis and identified an antimetastatic microRNA (miRNA), miR-139, that is down-regulated in human HCC samples. METHODS: Effects of stab... HIV-Tat-Mediated Delivery of an LPTS Functional Fragment Inhibits Telomerase Activity and Tumorigenicity of Hepatoma Cells [作者：Chen, GM; Da, LA; Wang, HF; Xu, Y; Chen, GY; Sun, CF; Wang, LM; Zhao, J; Zhang, F; Feng, JA; Wang, YF; Tiollais, P; Li, TP; Zhao, MJ,期刊：Gastroenterology, 页码：332-343 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Human liver-related putative tumor suppressor (LPTS) is a gene that encodes a telomerase inhibitory protein that is similar to human Pin2/TRF1-interacting protein. The LPTS protein binds directly to th... Combined Bicarbonate Conductance-Impairing Variants in CFTR and SPINK1 Variants Are Associated With Chronic Pancreatitis in Patients Without Cystic Fibrosis [作者：Schneider, A; Larusch, J; Sun, XM; Aloe, A; Lamb, J; Hawes, R; Cotton, P; Brand, RE; Anderson, MA; Money, ME; Banks, PA; Lewis, MD; Baillie, J; Sherman, S; Disario, J; Burton, FR; Gardner, TB; Amann, ST; Gelrud, A; George, R; Rockacy, MJ; Kassabian, S; Martinson, J; Slivka, A; Yadav, D; Oruc, N; Barmada, MM; Frizzell, R; Whitcomb, DC,期刊：Gastroenterology, 页码：162-171 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Idiopathic chronic pancreatitis (ICP) is a complex inflammatory disorder associated with multiple genetic and environmental factors. In individuals without cystic fibrosis (CF), variants of CFTR that i... Endoscopic Ultrasonography-Guided Ethanol Lavage With Paclitaxel Injection Treats Patients With Pancreatic Cysts [作者：Oh, HC; Seo, DW; Song, TJ; Moon, SH; Park, DH; Lee, SS; Lee, SK; Kim, MH; Kim, J,期刊：Gastroenterology, 页码：172-179 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Endoscopic ultrasonography (EUS)-guided interventions have been used to treat patients with cystic lesions of the pancreas (CLPs). We used EUS to guide injection and lavage of ethanol, followed by inje... Granulin-Epithelin Precursor and ATP-Dependent Binding Cassette (ABC)B5 Regulate Liver Cancer Cell Chemoresistance [作者：Cheung, ST; Cheung, PFY; Cheng, CKC; Wong, NCL; Fan, ST,期刊：Gastroenterology, 页码：344-+ , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Chemotherapy is used to treat unresectable liver cancer with marginal efficacy; this might result from hepatic cancer cells with stem cell and chemoresistant features. Gene expression profiling studies... Bone Disease in Patients With Primary Sclerosing Cholangitis [作者：Angulo, P; Grandison, GA; Fong, DG; Keach, JC; Lindor, KD; Bjornsson, E; Koch, A,期刊：Gastroenterology, 页码：180-188 , 文章类型： Article，,卷期：2011年140-1] BACKGROUND & AIMS: Osteopenic bone disease occurs frequently among patients with chronic liver disease but has not been well studied in those with primary sclerosing cholangitis (PSC). We investigated the prevalence, rat...