- Synthesis and Antitumor Activity of Ellagic Acid Peracetate
[作者:REN YULIN; WEI MIN; STILL PATRICK C; YUAN SHUNZONG; DENG YOUCAI; CHEN XIAOZHUO; HIMMELDIRK KLAUS; KINGHORN A DOUGLAS; YU JIANHUA,期刊:ACS Medicinal Chemistry Letters, 页码:631-636 , 文章类型: Article,,卷期:2012年3-8]
- Ellagic acid (1) was synthesized for the first time from methyl gallate through a-pentagalloylglucose (alpha-PGG), and ellagic acid peracetate (3,4,3',4'-tetra-O-acetylellagic acid, 2) was derived from 1 by acetylation. ...
- Brain Penetrant LRRK2 Inhibitor
[作者:CHOI HWAN GEUN; ZHANG JINWEI; DENG XIANMING; HATCHER JOHN M; PATRICELLI MATTHEW P; ZHAO ZHENG; ALESSI DARIO R; GRAY NATHANAEL S,期刊:ACS Medicinal Chemistry Letters, 页码:658-662 , 文章类型: Article,,卷期:2012年3-8]
- Activating mutations in leucine-rich repeat kinase 2 (LARK2) are present in a subset of Parkinson's disease (PD) patients and may represent an attractive therapeutic target. Here, we report that a 2-anilino-4-methylamino...
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