- MicroRNAs: Small RNAs With Big Effects
[作者:Anglicheau, D; Muthukumar, T; Suthanthiran, M,期刊:Transplantation, 页码:105-112 , 文章类型: Review,,卷期:2010年90-2]
- MicroRNAs (miRNAs) are evolutionarily conserved, small (similar to 20-25 nucleotides), single-stranded molecules that suppress the expression of protein-coding genes by translational repression, messenger RNA degradation...
- Advancement of Mesenchymal Stem Cell Therapy in Solid Organ Transplantation (MISOT)
[作者:Hoogduijn, MJ; Popp, FC; Grohnert, A; Crop, MJ; van Rhijn, M; Rowshani, AT; Eggenhofer, E; Renner, P; Reinders, ME; Rabelink, TJ; van der Laan, LJW; Dor, FJMF; IJzermans, JNM; Genever, PG; Lange, C; Durrbach, A; Houtgraaf, JH; Christ, B; Seifert, M; Shagidulin, M; Donckier, V; Deans, R; Ringden, O; Perico, N; Remuzzi, G; Bartholomew, A; Schlitt, HJ; Weimar, W; Baan, CC; Dahlke, MH,期刊:Transplantation, 页码:124-126 , 文章类型: Article,,卷期:2010年90-2]
- There is evolving interest in the use of mesenchymal stem cells (MSC) in solid organ transplantation. Pre-clinical transplantation models show efficacy of MSC in prolonging graft survival and a number of clinical studies...
- Role of Cholangiocyte Bile Acid Transporters in Large Bile Duct Injury After Rat Liver Transplantation
[作者:Cheng, L; Zhao, LJ; Li, DJ; Liu, ZP; Chen, G; Tian, F; Li, XW; Wang, SG,期刊:Transplantation, 页码:127-134 , 文章类型: Article,,卷期:2010年90-2]
- Background. The pathogenesis of nonanastomotic strictures with a patent hepatic artery remains to be investigated. This study focuses on the role of cholangiocyte bile acid transporters in bile duct injury after liver tr...
- Effect of Sirolimus on Calcineurin Inhibitor-Induced Nephrotoxicity Using Renal Expression of KLOTHO, an Antiaging Gene
[作者:Han, DH; Piao, SG; Song, JH; Ghee, JY; Hwang, HS; Choi, BS; Kim, J; Yang, CW,期刊:Transplantation, 页码:135-141 , 文章类型: Article,,卷期:2010年90-2]
- Background. The aim of this study was to observe the effect of sirolimus (SRL) on calcineurin inhibitor (CNI)-induced nephrotoxicity in the aging process by using renal expression of KLOTHO, an antiaging gene.Methods. Mi...
- Flow Cessation Triggers Endothelial Dysfunction During Organ Cold Storage Conditions: Strategies for Pharmacologic Intervention
[作者:Gracia-Sancho, J; Villarreal, G; Zhang, YZ; Yu, JX; Liu, Y; Tullius, SG; Garcia-Cardena, G,期刊:Transplantation, 页码:142-149 , 文章类型: Article,,卷期:2010年90-2]
- Background. Vascular pathologies constitute a major cause of graft rejection after organ transplantation. Recent studies have documented an improvement in transplant outcome when organs are preserved through pulsatile pe...
- Potent Immunosuppression by a Bivalent Molecule Binding to CD200R and TGF-beta R
[作者:Gorczynski, RM; Chen, ZQ; Shivagnahnam, S; Taseva, A; Wong, K; Yu, K; Khatri, I,期刊:Transplantation, 页码:150-159 , 文章类型: Article,,卷期:2010年90-2]
- Background. The novel immunosuppressive molecule, CD200, has been reported to induce immunoregulation after interaction with its receptor(s), CD200R(s), in part at least through augmented induction of regulatory T-cell p...
- Donor-Specific Antibody Levels and Three Generations of Crossmatches to Predict Antibody-Mediated Rejection in Kidney Transplantation
[作者:Riethmuller, S; Ferrari-Lacraz, S; Muller, MK; Raptis, DA; Hadaya, K; Rusi, B; Laube, G; Schneiter, G; Fehr, T; Villard, J,期刊:Transplantation, 页码:160-167 , 文章类型: Article,,卷期:2010年90-2]
- Background. This study evaluated the prognostic impact of pretransplant donor-specific anti-human leukocyte antigen antibodies (DSA) detected by single-antigen beads and compared the three generations of crossmatch (XM) ...
- Major Histocompatibility Complex Class 1 Chain-Related Antigen A Antibodies: Sensitizing Events and Impact on Renal Graft Outcomes
[作者:Lemy, A; Andrien, M; Wissing, KM; Ryhahi, K; Vandersarren, A; Racape, J; Heylen, C; Ghisdal, L; Broeders, E; Vereerstraeten, P; Toungouz, M; Abramowicz, D,期刊:Transplantation, 页码:168-174 , 文章类型: Article,,卷期:2010年90-2]
- Background. Major histocompatibility complex class 1 chain-related antigen A (MICA) antibodies (Abs) have been associated with renal graft loss in one large cohort. The triggering factors for MICA Abs and their autologou...
- Renal Function, Efficacy, and Safety of Sirolimus and Mycophenolate Mofetil After Short-Term Calcineurin Inhibitor-Based Quadruple Therapy in De Novo Renal Transplant Patients: One-Year Analysis of a Randomized Multicenter Trial
[作者:Guba, M; Pratschke, J; Hugo, C; Kramer, BK; Nohr-Westphal, C; Brockmann, J; Andrassy, J; Reinke, P; Pressmar, K; Hakenberg, O; Fischereder, M; Pascher, A; Illner, WD; Banas, B; Jauch, KW,期刊:Transplantation, 页码:175-183 , 文章类型: Article,,卷期:2010年90-2]
- Background. De novo sirolimus in calcineurin inhibitor-free regimens, although potentially useful to improve early renal function, are complicated by various drug-related side effects.Methods. We report a prospective ope...
- Transplant Tourism Outcome: A Single Center Experience
[作者:Alghamdi, SA; Nabi, ZG; Alkhafaji, DM; Askandrani, SA; Abdelsalam, MS; Shukri, MM; Eldali, AM; Adra, CN; Alkurbi, LA; Albaqumi, MN,期刊:Transplantation, 页码:184-188 , 文章类型: Article,,卷期:2010年90-2]
- Background. Transplant tourism is the term used for patients who travel abroad for transplantation. Transplant tourism has always been surrounded with controversy regarding how these organs were obtained, the donor's car...
- Validation of Noninvasive Diagnosis of BK Virus Nephropathy and Identification of Prognostic Biomarkers
[作者:Dadhania, D; Snopkowski, C; Ding, RC; Muthukumar, T; Lee, J; Bang, H; Sharma, VK; Seshan, S; August, P; Kapur, S; Suthanthiran, M,期刊:Transplantation, 页码:189-197 , 文章类型: Article,,卷期:2010年90-2]
- Background. BK virus nephropathy (BKVN) may cause renal allograft dysfunction and failure. The gold standard test is kidney biopsy, which is invasive and costly. A noninvasive, accurate biomarker for diagnosis of BKVN an...
- Adenovirus Infections in Pediatric Small Bowel Transplant Recipients
[作者:Florescu, DF; Islam, MK; Mercer, DF; Grant, W; Langnas, AN; Freifeld, AG; Sudan, D; Basappa, R; Dimaio, D; Kalil, AC,期刊:Transplantation, 页码:198-204 , 文章类型: Article,,卷期:2010年90-2]
- Background. Adenovirus is commonly isolated from pediatric small bowel transplant recipients, but its clinical consequences remain poorly understood.Methods. The medical records of pediatric small bowel transplant recipi...
- The Psychometric Properties and Practicability of Self-Report Instruments to Identify Medication Nonadherence in Adult Transplant Patients: A Systematic Review
[作者:Dobbels, F; Berben, L; De Geest, S; Drent, G; Lennerling, A; Whittaker, C; Kugler, C,期刊:Transplantation, 页码:205-219 , 文章类型: Article,,卷期:2010年90-2]
- Introduction. Nonadherence to immunosuppressive therapy is recognized as a key prognostic indicator for poor posttransplantation long-term outcomes. Several methods aiming to measure medication nonadherence have been sug...
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