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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共10条记录   Calcification of multipotent prostate tumor endothelium [作者：Dudley, AC; Khan, ZA; Shih, SC; Kang, SY; Zwaans, BMM; Bischoff, J; Klagsbrun, M,期刊：Cancer Cell, 页码：201-211 , 文章类型： Article，,卷期：2008年14-3] Solid tumors require new blood vessels for growth and metastasis, yet the biology of tumor-specific endothelial cells is poorly understood. We have isolated tumor endothelial cells from mice that spontaneously develop pr... IKK alpha is required to maintain skin homeostasis and prevent skin cancer [作者：Liu, BG; Xia, XJ; Zhu, F; Park, E; Carbajal, S; Kiguchi, K; DiGiovanni, J; Fischer, SM; Hu, YL,期刊：Cancer Cell, 页码：212-225 , 文章类型： Article，,卷期：2008年14-3] It has long been known that excessive mitotic activity due to H-Ras can block keratinocyte differentiation and cause skin cancer. It is not clear whether there are any innate surveillants that are able to ensure that ker... RUNX3 attenuates beta-catenin/T cell factors in intestinal tumorigenesis [作者：Ito, K; Lim, ACB; Salto-Tellez, M; Motoda, L; Osato, M; Shyue, L; Chuang, H; Lee, CWL; Voon, DCC; Koo, JKW; Wang, HJ; Fukamachi, H; Ito, Y,期刊：Cancer Cell, 页码：226-237 , 文章类型： Article，,卷期：2008年14-3] In intestinal epithelial cells, inactivation of APC, a key regulator of the Wnt pathway, activates beta-catenin to initiate tumorigenesis. However, other alterations may be involved in intestinal tumorigenesis. Here we f... Expansion of Bcr-Abl-positive leukemic stem cells is dependent on hedgehog pathway activation [作者：Dierks, C; Beigi, R; Guo, GR; Zirlik, K; Stegert, MR; Manley, P; Trussell, C; Schmitt-Graeff, A; Landwerlin, K; Veelken, H; Warmuth, M,期刊：Cancer Cell, 页码：238-249 , 文章类型： Article，,卷期：2008年14-3] Resistance of Bcr-Abl-positive leukemic stem cells (LSCs) to imatinib treatment in patients with chronic myeloid leukemia (CIVIL) can cause relapse of disease and might be the origin for emerging drug-resistant clones. I... Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis [作者：Powers, MV; Clarke, PA; Workman, P,期刊：Cancer Cell, 页码：250-262 , 文章类型： Article，,卷期：2008年14-3] Heat-shock protein 70 (HSP70) isoforms contribute to tumorigenesis through their well-documented antiapoptotic activity and via their role as cochaperones for the HSP90 molecular chaperone. HSP70 expression is induced fo... Rapid chemotherapy-induced acute endothelial progenitor cell mobilization: Implications for antiangiogenic drugs as chemosensitizing agents [作者：Shaked, Y; Henke, E; Roodhart, JML; Mancuso, P; Langenberg, MHG; Colleoni, M; Daenen, LG; Man, S; Xu, P; Emmenegger, U; Tang, T; Zhu, ZP; Witte, L; Strieter, RM; Bertolini, F; Voest, EE; Benezra, R; Kerbell, RS,期刊：Cancer Cell, 页码：263-273 , 文章类型： Article，,卷期：2008年14-3] Several hypotheses have been proposed to explain how antiangiogenic drugs enhance the treatment efficacy of cytotoxic chemotherapy, including impairing the ability of chemotherapy-responsive tumors to regrow after therap... The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells (vol 9, pg 209, 2006) [作者：Su, JL; Yang, PC; Shih, JY; Yang, CY; Wei, LH; Hsieh, CY; Chou, CH; Jeng, YM; Wang, MY; Chang, KJ; Hung, MC; Kuo, ML,期刊：Cancer Cell, 页码：274-277 , 文章类型： Correction，,卷期：2008年14-3] Bony endothelium: Tumor-mediated transdifferentiation? [作者：Verfaillie, CM,期刊：Cancer Cell, 页码：193-194 , 文章类型： Editorial Material，,卷期：2008年14-3] In this issue of Cancer Cell, Dudley et al. (2008) report that endothelial cells (ECs)from murine prostate tumors unexpectedly differentiate into cells with characteristics of bone and cartilage and that human and murine... Redefining the target again: Chemotherapeutics as vascular disrupting agents? [作者：Gokmen-Polar, Y; Miller, KD,期刊：Cancer Cell, 页码：195-196 , 文章类型： Editorial Material，,卷期：2008年14-3] In this issue of Cancer Cell, Shaked et al. (2008) provide novel mechanistic evidence that some chemotherapeutics induce circulating endothelial progenitor (CEP) mobilization with subsequent homing to tumor vasculature. ... Actin and microtubules: Working together to control spindle polarity [作者：Xu, FL; Saunders, WS,期刊：Cancer Cell, 页码：197-199 , 文章类型： Editorial Material，,卷期：2008年14-3] Centrosomes are frequently amplified in cancer cells, but centrosome clustering pathways act to minimize their detrimental impact on mitosis. Recent data published online in Genes & Developments by Kwon et al. (2008) sug...