- H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias
[作者：Krivtsov, AV; Feng, Z; Lemieux, ME; Faber, J; Vempati, S; Sinha, AU; Xia, X; Jesneck, J; Bracken, AP; Silverman, LB; Kutok, JL; Kung, AL; Armstrong, SA,期刊：Cancer Cell, 页码：355-368 , 文章类型： Article，,卷期：2008年14-5]
- We created a mouse model wherein conditional expression of an MII-AF4 fusion oncogene induces B precursor acute lymphoblastic (ALL) or acute myeloid leukemias (AML). Gene expression profile analysis of the ALL cells demo...
- miR-296 Regulates Growth Factor Receptor Overexpression in Angiogenic Endothelial Cells
[作者：Wurdinger, T; Tannous, BA; Saydam, O; Skog, J; Grau, S; Soutschek, J; Weissleder, R; Breakefield, XO; Krichevsky, AM,期刊：Cancer Cell, 页码：382-393 , 文章类型： Article，,卷期：2008年14-5]
- A key step in angiogenesis is the upregulation of growth factor receptors on endothelial cells. Here, we demonstrate that a small regulatory microRNA, miR-296, has a major role in this process. Glioma cells and angiogeni...
- Inactivation of the CYLD Deubiquitinase by HPV E6 Mediates Hypoxia-Induced NF-kappa B Activation
[作者：An, J; Mo, D; Liu, H; Veena, MS; Srivatsan, ES; Massoumi, R; Rettig, MB,期刊：Cancer Cell, 页码：394-407 , 文章类型： Article，,卷期：2008年14-5]
- The biochemical mechanisms that underlie hypoxia-induced NF-kappa B activity have remained largely undefined. Here, we find that prolonged hypoxia-induced NF-kappa B activation is restricted to cancer cell lines infected...
- NF-kappa B-YY1-miR-29 Regulatory Circuitry in Skeletal Myogenesis and Rhabdomyosarcoma
[作者：Wang, H; Garzon, R; Sun, H; Ladner, KJ; Singh, R; Dahlman, J; Cheng, A; Hall, BM; Qualman, SJ; Chandler, DS; Croce, CM; Guttridge, DC,期刊：Cancer Cell, 页码：369-381 , 文章类型： Article，,卷期：2008年14-5]
- Studies support the importance of microRNAs in physiological and pathological processes. Here we describe the regulation and function of miR-29 in myogenesis and rhabdomyosarcoma (RMS). Results demonstrate that in myobla...
- Overexpression of Interleukin-1 beta Induces Gastric Inflammation and Cancer and Mobilizes Myeloid-Derived Suppressor Cells in Mice
[作者：Tu, S; Bhagat, G; Cui, G; Takaishi, S; Kurt-Jones, EA; Rickman, B; Betz, KS; Penz-Oesterreicher, M; Bjorkdahl, O; Fox, JG; Wang, TC,期刊：Cancer Cell, 页码：408-419 , 文章类型： Article，,卷期：2008年14-5]
- Polymorphisms of interleukin-1 beta (IL-1 beta) are associated with an increased risk of solid malignancies. Here, we show that stomach-specific expression of human IL-1 beta in transgenic mice leads to spontaneous gastr...
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