- Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons
[作者:Son, EY; Ichida, JK; Wainger, BJ; Toma, JS; Rafuse, VF; Woolf, CJ; Eggan, K,期刊:Cell Stem Cell, 页码:205-218 , 文章类型: Article,,卷期:2011年9-3]
- The mammalian nervous system comprises many distinct neuronal subtypes, each with its own phenotype and differential sensitivity to degenerative disease. Although specific neuronal types can be isolated from rodent embry...
- Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage
[作者:Lien, WH; Guo, XY; Polak, L; Lawton, LN; Young, RA; Zheng, DY; Fuchs, E,期刊:Cell Stem Cell, 页码:219-232 , 文章类型: Article,,卷期:2011年9-3]
- Using mouse skin, where bountiful reservoirs of synchronized hair follicle stem cells (HF-SCs) fuel cycles of regeneration, we explore how adult SCs remodel chromatin in response to activating cues. By profiling global m...
- Regulation of Human Epidermal Stem Cell Proliferation and Senescence Requires Polycomb-Dependent and -Independent Functions of Cbx4
[作者:Luis, NM; Morey, L; Mejetta, S; Pascual, G; Janich, P; Kuebler, B; Roma, G; Nascimento, E; Frye, M; Di Croce, L; Benitah, SA,期刊:Cell Stem Cell, 页码:233-246 , 文章类型: Article,,卷期:2011年9-3]
- Human epidermal stem cells transit from a slow cycling to an actively proliferating state to contribute to homeostasis. Both stem cell states differ in their cell cycle profiles but must remain guarded from differentiati...
- p57(KiP2) and p27(Kip1) Cooperate to Maintain Hematopoietic Stem Cell Quiescence through Interactions with Hsc70
[作者:Zou, P; Yoshihara, H; Hosokawa, K; Tai, I; Shinmyozu, K; Tsukahara, F; Maru, Y; Nakayama, K; Nakayama, KI; Suda, T,期刊:Cell Stem Cell, 页码:247-261 , 文章类型: Article,,卷期:2011年9-3]
- Cell cycle regulators play critical roles in the balance between hematopoietic stem cell (HSC) dormancy and proliferation. In this study, we report that cell cycle entry proceeded normally in HSCs null for cyclin-depende...
- p57 Is Required for Quiescence and Maintenance of Adult Hematopoietic Stem Cells
[作者:Matsumoto, A; Takeishi, S; Kanie, T; Susaki, E; Onoyama, I; Tateishi, Y; Nakayama, K; Nakayama, KI,期刊:Cell Stem Cell, 页码:262-271 , 文章类型: Article,,卷期:2011年9-3]
- Quiescence is required for the maintenance of hematopoietic stem cells (HSCs). Members of the Cip/Kip family of cyclin-dependent kinase (CDK) inhibitors (p21, p27, p57) have been implicated in HSC quiescence, but loss of...
- Lung Stem Cell Self-Renewal Relies on BMI1-Dependent Control of Expression at Imprinted Loci
[作者:Zacharek, SJ; Fillmore, CM; Lau, AN; Gludish, DW; Chou, A; Ho, JWK; Zamponi, R; Gazit, R; Bock, C; Jager, N; Smith, ZD; Kim, TM; Saunders, AH; Wong, J; Lee, JH; Roach, RR; Rossi, DJ; Meissner, A; Gimelbrant, AA; Park, PJ; Kim, CF,期刊:Cell Stem Cell, 页码:272-280 , 文章类型: Article,,卷期:2011年9-3]
- BMI1 is required for the self-renewal of stem cells in many tissues including the lung epithelial stem cells, Bronchioalveolar Stem Cells (BASCs). Imprinted genes, which exhibit expression from only the maternally or pat...
|