- Small RNAs Loom Large During Reprogramming
[作者：Sridharan, R; Plath, K,期刊：Cell Stem Cell, 页码：599-601 , 文章类型： Editorial Material，,卷期：2011年8-6]
- In two independent Cell Stem Cell reports, the Morrisey and Mori groups show that human and mouse somatic cells can be reprogrammed to produce induced pluripotent stem cells by expressing microRNAs, completely eliminatin...
- Taking HSCs Down a Notch in Leukemia
[作者：Walkley, CR; Izon, DJ; Purton, LE,期刊：Cell Stem Cell, 页码：602-603 , 文章类型： Editorial Material，,卷期：2011年8-6]
- The Notch signaling pathway is activated in the majority of T cell acute lymphoblastic leukemias (T-ALL). Adding to the complexity of Notch signaling in hematopoiesis, recently in Nature, Klinakis et al. (2011) demonstra...
- Researching the Relationships between Tissue Providers, Clinicians, and Stem Cell Scientists
[作者：Haimes, E; Taylor, K,期刊：Cell Stem Cell, 页码：613-615 , 文章类型： Editorial Material，,卷期：2011年8-6]
- Access to human reproductive tissue is essential for many forms of stem cell research. We identify questions for future studies of tissue providers, procurers, and end-user scientists, and suggest that international comp...
- Assessing the Safety of Stem Cell Therapeutics
[作者：Goldring, CEP; Duffy, PA; Benvenisty, N; Andrews, PW; Ben-David, U; Eakins, R; French, N; Hanley, NA; Kelly, L; Kitteringham, NR; Kurth, J; Ladenheim, D; Laverty, H; McBlane, J; Narayanan, G; Patel, S; Reinhardt, J; Rossi, A; Sharpe, M; Park, BK,期刊：Cell Stem Cell, 页码：618-628 , 文章类型： Editorial Material，,卷期：2011年8-6]
- Unprecedented developments in stem cell research herald a new era of hope and expectation for novel therapies. However, they also present a major challenge for regulators since safety assessment criteria, designed for co...
- Reprogramming of Mouse and Human Cells to Pluripotency Using Mature MicroRNAs
[作者：Miyoshi, N; Ishii, H; Nagano, H; Haraguchi, N; Dewi, DL; Kano, Y; Nishikawa, S; Tanemura, M; Mimori, K; Tanaka, F; Saito, T; Nishimura, J; Takemasa, I; Mizushima, T; Ikeda, M; Yamamoto, H; Sekimoto, M; Doki, Y; Mori, M,期刊：Cell Stem Cell, 页码：633-638 , 文章类型： Article，,卷期：2011年8-6]
- Induced pluripotent stem cells (iPSCs) can be generated from differentiated human and mouse somatic cells using transcription factors such as Oct4, Sox2, Klf4, and c-Myc. It is possible to augment the reprogramming proce...
- Notch-Dependent Differentiation of Adult Airway Basal Stem Cells
[作者：Rock, JR; Gao, X; Xue, Y; Randell, SH; Kong, YY; Hogan, BLM,期刊：Cell Stem Cell, 页码：639-648 , 文章类型： Article，,卷期：2011年8-6]
- The epithelium lining the airways of the adult human lung is composed of ciliated and secretory cells together with undifferentiated basal cells (BCs). The composition and organization of this epithelium is severely disr...
- Functional Crosstalk between Bmi1 and MLL/Hoxa9 Axis in Establishment of Normal Hematopoietic and Leukemic Stem Cells
[作者：Smith, LL; Yeung, J; Zeisig, BB; Popov, N; Huijbers, I; Barnes, J; Wilson, AJ; Taskesen, E; Delwel, R; Gil, J; Van Lohuizen, M; So, CWE,期刊：Cell Stem Cell, 页码：649-662 , 文章类型： Article，,卷期：2011年8-6]
- Bmi1 is required for efficient self-renewal of hematopoietic stem cells (HSCs) and leukemic stem cells (LSCs). In this study, we investigated whether leukemia-associated fusion proteins, which differ in their ability to ...
- Transcription Factor-Induced Lineage Selection of Stem-Cell-Derived Neural Progenitor Cells
[作者：Panman, L; Andersson, E; Alekseenko, Z; Hedlund, E; Kee, N; Mong, J; Uhde, CW; Deng, QL; Sandberg, R; Stanton, LW; Ericson, J; Perlmann, T,期刊：Cell Stem Cell, 页码：663-675 , 文章类型： Article，,卷期：2011年8-6]
- The generation of specific types of neurons from stem cells offers important opportunities in regenerative medicine. However, future applications and proper verification of cell identities will require stringent ways to ...
- DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs
[作者：Karimi, MM; Goyal, P; Maksakova, IA; Bilenky, M; Leung, D; Tang, JX; Shinkai, Y; Mager, DL; Jones, S; Hirst, M; Lorincz, MC,期刊：Cell Stem Cell, 页码：676-687 , 文章类型： Article，,卷期：2011年8-6]
- DNA methylation and histone H3 lysine 9 trimethylation (H3K9me3) play important roles in silencing of genes and retroelements. However, a comprehensive comparison of genes and repetitive elements repressed by these pathw...
- Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs
[作者：Liu, GH; Suzuki, K; Qu, J; Sancho-Martinez, I; Yi, F; Li, M; Kumar, S; Nivet, E; Kim, J; Soligalla, RD; Dubova, I; Goebl, A; Plongthongkum, N; Fung, HL; Zhang, K; Loring, JF; Laurent, LC; Belmonte, JCI,期刊：Cell Stem Cell, 页码：688-694 , 文章类型： Article，,卷期：2011年8-6]
- Combination of stem cell-based approaches with gene-editing technologies represents an attractive strategy for studying human disease and developing therapies. However, gene-editing methodologies described to date for hu...
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