- An alternative spliced mouse presenilin-2 mRNA encodes a novel gamma-secretase inhibitor
[作者:Suzuki, Y; Ohta, K; Itoh, M; Sakoh-Sumitomo, Y; Mitsuda, T; Ueda, M; Hayakawa-Yano, Y; Li, SM; Hida, Y; Inuzuka, T; Jung, YK; Nakagawa, T,期刊:FEBS Letters, 页码:1403-1408 , 文章类型: Article,,卷期:2009年583-9]
- The gamma-secretase, composed of presenilin-1 (PS1) or presenilin-2 (PS2), nicastrin (NCT), anterior pharynx-defective phenotype 1 (APH-1), and PEN-2, is critical for the development of Alzheimer's disease (AD). PSs are ...
- HSP70 protects BCL2L12 and BCL2L12A from N-terminal ubiquitination-mediated proteasomal degradation
[作者:Yang, JW; Hong, Y; Wang, WZ; Wu, WB; Chi, YY; Zong, HL; Kong, XF; Wei, YY; Yun, XJ; Cheng, CM; Chen, KL; Gu, JX,期刊:FEBS Letters, 页码:1409-1414 , 文章类型: Article,,卷期:2009年583-9]
- BCL2L12 has been found to be associated with favorable prognosis in breast cancer patients while correlated with tumorigenesis of glioblastoma and colon cancer. Here, we report that BCL2L12 and its transcript variant BCL...
- High throughput sequencing of microRNAs in chicken somites
[作者:Rathjen, T; Pais, H; Sweetman, D; Moulton, V; Munsterberg, A; Dalmay, T,期刊:FEBS Letters, 页码:1422-1426 , 文章类型: Article,,卷期:2009年583-9]
- High throughput Solexa sequencing technology was applied to identify microRNAs in somites of developing chicken embryos. We obtained 651273 reads, from which 340415 were mapped to the chicken genome representing 1701 dis...
- Conformational change induced by ATP binding correlates with enhanced biological function of Arabidopsis cryptochrome
[作者:Burney, S; Hoang, N; Caruso, M; Dudkin, EA; Ahmad, M; Bouly, JP,期刊:FEBS Letters, 页码:1427-1433 , 文章类型: Article,,卷期:2009年583-9]
- Cryptochromes are widely distributed blue light photoreceptors involved in numerous signaling functions in plants and animals. Both plant and animal-type cryptochromes are found to bind ATP and display intrinsic autokina...
- Oncostatin M synergistically inhibits HCV RNA replication in combination with interferon-alpha
[作者:Ikeda, M; Mori, K; Ariumi, Y; Dansako, H; Kato, N,期刊:FEBS Letters, 页码:1434-1438 , 文章类型: Article,,卷期:2009年583-9]
- Oncostatin M (OSM), a member of the interleukin-6 family, possesses various functions, including hepatocyte differentiation and suppression of melanoma cell growth. Here, we report anti-hepatitis C virus (HCV) activity o...
- The Plasmodium HU homolog, which binds the plastid DNA sequence-independent manner, is essential for the parasite's survival
[作者:Sasaki, N; Hirai, M; Maeda, K; Yui, R; Itoh, K; Namiki, S; Morita, T; Hata, M; Murakami-Murofushi, K; Matsuoka, H; Kita, K; Sato, S,期刊:FEBS Letters, 页码:1446-1450 , 文章类型: Article,,卷期:2009年583-9]
- The nuclear genome of the human malaria parasite Plasmodium falciparum encodes a homolog of the bacterial HU protein (PfHU). In this study, we characterised PfHU's physiological function. PfHU, which is targeted exclusiv...
- A novel family of hemicellulolytic alpha-glucuronidase
[作者:Ryabova, O; Vrsanska, M; Kaneko, S; van Zyl, WH; Biely, P,期刊:FEBS Letters, 页码:1457-1462 , 文章类型: Article,,卷期:2009年583-9]
- Investigation of the xylanolytic enzyme system of the xylose-fermenting yeast Pichia stipitis resulted in the discovery of an extracellular alpha-glucuronidase efficiently debranching hardwood glucuronoxylan. This activi...
- Molecular and functional characterization of adipokinetic hormone receptor and its peptide ligands in Bombyx mori
[作者:Zhu, CG; Huang, HS; Hua, RS; Li, G; Yang, D; Luo, JS; Zhang, CX; Shi, LG; Benovic, JL; Zhou, NM,期刊:FEBS Letters, 页码:1463-1468 , 文章类型: Article,,卷期:2009年583-9]
- Neuropeptides of the adipokinetic hormone (AKH) family are among the best studied hormone peptides, but its signaling pathways remain to be elucidated. In this study, we molecularly characterized the signaling of Bombyx ...
- Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells
[作者:Bukoreshtliev, NV; Wang, X; Hodneland, E; Gurke, S; Barroso, JFV; Gerdes, HH,期刊:FEBS Letters, 页码:1481-1488 , 文章类型: Article,,卷期:2009年583-9]
- Organelle exchange between cells via tunneling nanotubes (TNTs) is a recently described form of intercellular communication. Here, we show that the selective elimination of filopodia from PC12 cells by 350 nM cytochalasi...
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