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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共19条记录   The ins and outs of cells [作者：ANONYMOUS,期刊：NATURE CHEMICAL BIOLOGY, 页码：479-479 , 文章类型： Editorial Material，,卷期：2011年7-8] Principles for designing fluorescent sensors and reporters [作者：LEMKE EDWARD A; SCHULTZ CARSTEN,期刊：NATURE CHEMICAL BIOLOGY, 页码：480-483 , 文章类型： Editorial Material，,卷期：2011年7-8] Principles of a switch [作者：PTASHNE MARK,期刊：NATURE CHEMICAL BIOLOGY, 页码：484-487 , 文章类型： Editorial Material，,卷期：2011年7-8] Sensing cellular stress through STIM proteins [作者：SOBOLOFF JONATHAN; MADESH MUNISWAMY; GILL DONALD L,期刊：NATURE CHEMICAL BIOLOGY, 页码：488-492 , 文章类型： Editorial Material，,卷期：2011年7-8] Chronicles of the GTPase switch [作者：CHERFILS JACQUELINE; ZEGHOUF MAHEL,期刊：NATURE CHEMICAL BIOLOGY, 页码：493-495 , 文章类型： Editorial Material，,卷期：2011年7-8] TRANSPORT Plutonium's Trojan horse [作者：KOSMAN DANIEL J,期刊：NATURE CHEMICAL BIOLOGY, 页码：498-499 , 文章类型： News Item，,卷期：2011年7-8] CHEMICAL PROBES Sharpen your epigenetic tools [作者：HAUSER ALEXANDERTHOMAS; JUNG MANFRED,期刊：NATURE CHEMICAL BIOLOGY, 页码：499-500 , 文章类型： News Item，,卷期：2011年7-8] RECEPTORS Clicking class B GPCR ligands [作者：SAKMAR THOMAS P,期刊：NATURE CHEMICAL BIOLOGY, 页码：500-501 , 文章类型： News Item，,卷期：2011年7-8] MICROBIOLOGY Tuning communication fidelity [作者：JUNG KIRSTEN,期刊：NATURE CHEMICAL BIOLOGY, 页码：502-503 , 文章类型： News Item，,卷期：2011年7-8] Chemistry and biology of reactive oxygen species in signaling or stress responses [作者：DICKINSON BRYAN C; CHANG CHRISTOPHER J,期刊：NATURE CHEMICAL BIOLOGY, 页码：504-511 , 文章类型： Article，,卷期：2011年7-8] Reactive oxygen species (ROS) are a family of molecules that are continuously generated, transformed and consumed in all living organisms as a consequence of aerobic life. The traditional view of these reactive oxygen me... AMP-activated protein kinase: nature's energy sensor [作者：CARLING DAVID; MAYER FAITH V; SANDERS MATTHEW J; GAMBLIN STEVEN J,期刊：NATURE CHEMICAL BIOLOGY, 页码：512-518 , 文章类型： Article，,卷期：2011年7-8] Maintaining sufficient levels of ATP (the immediate source of cellular energy) is essential for the proper functioning of all living cells. As a consequence, cells require mechanisms to balance energy demand with supply.... Aptamers for allosteric regulation [作者：VINKENBORG JAN L; KARNOWSKI NORA; FAMULOK MICHAEL,期刊：NATURE CHEMICAL BIOLOGY, 页码：519-527 , 文章类型： Review，,卷期：2011年7-8] Aptamers are useful for allosteric regulation because they are nucleic acid-based structures in which ligand binding induces conformational changes that may alter the function of a connected oligonucleotide at a distant ... D-Ornithine coopts pyrrolysine biosynthesis to make and insert pyrroline-carboxy-lysine [作者：CELLITTI SUSAN E; OU WEIJIA; CHIU HSIENPO; GRUENEWALD JAN; JONES DAVID H; HAO XUESHI; FAN QIAN; QUINN LISA L; NG KENNETH; ANFORA ANDREW T; LESLEY SCOTT A; UNO TETSUO; BROCK ANSGAR; GEIERSTANGER BERNHARD H,期刊：NATURE CHEMICAL BIOLOGY, 页码：528-530 , 文章类型： Article，,卷期：2011年7-8] D-Ornithine has previously been suggested to enhance the expression of pyrrolysine-containing proteins. We unexpectedly discovered that uptake of D-ornithine results in the insertion of a new amino acid, pyrroline-carbox... Small-molecule displacement of a cryptic degron causes conditional protein degradation [作者：BONGER KIMBERLY M; CHEN LINGCHUN; LIU COREY W; WANDLESS THOMAS J,期刊：NATURE CHEMICAL BIOLOGY, 页码：531-537 , 文章类型： Article，,卷期：2011年7-8] The ability to rapidly regulate the functions of specific proteins in living cells is a valuable tool for biological research. Here we describe a new technique by which the degradation of a specific protein is induced by... Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins [作者：NEKLESA TAAVI K; TAE HYUN SEOP; SCHNEEKLOTH ASHLEY R; STULBERG MICHAEL J; CORSON TIMOTHY W; SUNDBERG THOMAS B; RAINA KANAK; HOLLEY SCOTT A; CREWS CRAIG M,期刊：NATURE CHEMICAL BIOLOGY, 页码：538-543 , 文章类型： Article，,卷期：2011年7-8] The ability to regulate any protein of interest in living systems with small molecules remains a challenge. We hypothesized that appending a hydrophobic moiety to the surface of a protein would mimic the partially denatu... A screen for regulators of survival of motor neuron protein levels [作者：MAKHORTOVA NINA R; HAYHURST MONICA; CERQUEIRA ANTONIO; SINORANDERSON AMY D; ZHAO WENNING; HEISER PATRICK W; ARVANITES ANTHONY C; DAVIDOW LANCE S; WALDON ZACHARY O; STEEN JUDITH A; LAM KELVIN; NGO HIEN D; RUBIN LEE L,期刊：NATURE CHEMICAL BIOLOGY, 页码：544-552 , 文章类型： Article，,卷期：2011年7-8] The motor neuron disease spinal muscular atrophy (SMA) results from mutations that lead to low levels of the ubiquitously expressed protein survival of motor neuron (SMN). An ever-increasing collection of data suggests t...