- Urocanic acid-modified chitosan-mediated PTEN delivery via aerosol suppressed lung tumorigenesis in K-ras(LA1) mice
[作者:Jin, H; Xu, CX; Kim, HW; Chung, YS; Shin, JY; Chang, SH; Park, SJ; Lee, ES; Hwang, SK; Kwon, JT; Minai-Tehrani, A; Woo, M; Noh, MS; Youn, HJ; Kim, DY; Yoon, BI; Lee, KH; Kim, TH; Cho, S; Cho, MH,期刊:Cancer gene therapy, 页码:275-283 , 文章类型: Article,,卷期:2008年15-5]
- The low efficiency of conventional therapies in achieving long-term survival of lung cancer patients calls for development of novel options. Revisiting of aerosol gene delivery may provide an alternative for safe and eff...
- A cancer terminator virus eradicates both primary and distant human melanomas
[作者:Sarkar, D; Su, ZZ; Park, ES; Vozhilla, N; Dent, P; Curiel, DT; Fisher, PB,期刊:Cancer gene therapy, 页码:293-302 , 文章类型: Article,,卷期:2008年15-5]
- The prognosis and response to conventional therapies of malignant melanoma inversely correlate with disease progression. With increasing thickness, melanomas acquire metastatic potential and become inherently resistant t...
- Characterization of HIV-1 TAT peptide as an enhancer of HSV-TK/GCV cancer gene therapy
[作者:Rautsi, O; Lehmusvaara, S; Ketola, A; Maatta, AM; Wahlfors, J; Pellinen, R,期刊:Cancer gene therapy, 页码:303-314 , 文章类型: Article,,卷期:2008年15-5]
- Cancer suicide gene therapy based on herpes simplex virus type I thymidine kinase (HSV-TK) and ganciclovir (GCV) suffers from the lack of efficacy in clinical use, which is mostly due to low gene-transfer efficiency and ...
- Direct and distant antitumor effects of a telomerase-selective oncolytic adenoviral agent, OBP-301, in a mouse prostate cancer model
[作者:Huang, P; Watanabe, M; Kaku, H; Kashiwakura, Y; Chen, J; Saika, T; Nasu, Y; Fujiwara, T; Urata, Y; Kumon, H,期刊:Cancer gene therapy, 页码:315-322 , 文章类型: Article,,卷期:2008年15-5]
- We previously constructed OBP-301 ( Telomelysin, a telomerase-specific replication-competent adenovirus with human telomerase reverse transcriptase ( hTERT) promoter), which showed a strong anticancer effect by inducing ...
- Synergistic effect of 15-lipoxygenase 2 and radiation in killing head-and-neck cancer
[作者:Yang, Q; Feng, Y; Schultz, CJ; Li, XA; Wu, H; Wang, D,期刊:Cancer gene therapy, 页码:323-330 , 文章类型: Article,,卷期:2008年15-5]
- We previously demonstrated that 15-LOX-2 is significantly reduced in head and neck carcinoma and restoration of 15-LOX-2 expression results in tumor inhibition in HNC. The aim of this study is to evaluate 15-LOX-2 as a c...
- Targeted gene therapy of LS174T human colon carcinoma by anti-TAG-72 immunoliposomes
[作者:Kim, KS; Lee, YK; Kim, JS; Koo, KH; Hong, HJ; Park, YS,期刊:Cancer gene therapy, 页码:331-340 , 文章类型: Article,,卷期:2008年15-5]
- Anti-tumor-associated glycoprotein ( TAG)-72 PEG-immunoliposomes (PILs) were prepared by conjugation of Fab' fragments of recombinant humanized monoclonal antibody, HuCC49, to sterically stabilize unilamellar liposomes (...
- Transient infection of freshly isolated human colorectal tumor cells by reovirus T3D intermediate subviral particles
[作者:van Houdt, WJ; Smakman, N; van den Wollenberg, DJM; Emmink, BL; Veenendaal, LM; van Diest, PJ; Hoeben, RC; Rinkes, IHMB; Kranenburg, O,期刊:Cancer gene therapy, 页码:284-292 , 文章类型: Article,,卷期:2008年15-5]
- Reovirus T3D preferentially kills tumor cells expressing Ras oncogenes and has shown great promise as an anticancer agent in various preclinical tumor models. Here, we investigated whether reovirus can infect and kill tu...
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