- Dynamic Equilibrium and Heterogeneity of Mouse Pluripotent Stem Cells with Distinct Functional and Epigenetic States
[作者:Hayashi, K; Lopes, SMCD; Tang, F; Surani, MA,期刊:Cell Stem Cell, 页码:391-401 , 文章类型: Article,,卷期:2008年3-4]
- Embryonic stem cells (ESCs) are apparently homogeneous self-renewing cells, but we observed heterogeneous expression of Stella in ESCs, which is a marker of pluripotency and germ cells. Here we show that, whereas Stella-...
- Anterior Definitive Endoderm from ESCs Reveals a Role for FGF Signaling
[作者:Morrison, GM; Oikonomopoulou, I; Migueles, RP; Soneji, S; Livigni, A; Enver, T; Brickman, JM,期刊:Cell Stem Cell, 页码:402-415 , 文章类型: Article,,卷期:2008年3-4]
- The use of embryonic stem cell (ESC) differentiation to generate functional hepatic or pancreatic progenitors and as a tool for developmental biology is limited by an inability to isolate in vitro equivalents of regional...
- Hematopoietic Stem Cell Quiescence Is Maintained by Compound Contributions of the Retinoblastoma Gene Family
[作者:Viatour, P; Somervaille, TC; Venkatasubrahmanyam, S; Kogan, S; McLaughlin, ME; Weissman, IL; Butte, AJ; Passegue, E; Sage, J,期刊:Cell Stem Cell, 页码:416-428 , 文章类型: Article,,卷期:2008年3-4]
- Individual members of the retinoblastoma (Rb) tumor suppressor gene family serve critical roles in the control of cellular proliferation and differentiation, but the extent of their contributions is masked by redundant a...
- Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment
[作者:Bouras, T; Pal, B; Vaillant, F; Harburg, G; Asselin-Labat, ML; Oakes, SR; Lindeman, GJ; Visvader, JE,期刊:Cell Stem Cell, 页码:429-441 , 文章类型: Article,,卷期:2008年3-4]
- The recent identification of mouse mammary stem cells (MaSCs) and progenitor subpopulations has enhanced the prospect of investigating the genetic control of their lineage specification and differentiation. Here we have ...
- Identification of the Endostyle as a Stem Cell Niche in a Colonial Chordate
[作者:Voskoboynik, A; Soen, Y; Rinkevich, Y; Rosner, A; Ueno, H; Reshef, R; Ishizuka, KJ; Palmeri, KJ; Moiseeva, E; Rinkevich, B; Weissman, IL,期刊:Cell Stem Cell, 页码:456-464 , 文章类型: Article,,卷期:2008年3-4]
- Stem cell populations exist in "niches" that hold them and regulate their fate decisions. Identification and characterization of these niches is essential for understanding stem cell maintenance and tissue regeneration. ...
- Myeloproliferative Disorder by TKO
[作者:Adams, GB,期刊:Cell Stem Cell, 页码:361-362 , 文章类型: Editorial Material,,卷期:2008年3-4]
- In this issue of Cell Stem Cell, Viatour et al. (2008) delete all three members of the retinoblastoma tumor suppressor gene family in hematopoietic stem cells, resulting in a myeloproliferative disorder. The disease was ...
- Patterning Stem Cell Differentiation
[作者:Vunjak-Novakovic, G,期刊:Cell Stem Cell, 页码:362-363 , 文章类型: Editorial Material,,卷期:2008年3-4]
Regulation of cell differentiation and assembly remains a fundamental question in developmental biology. Now, a report from the Chen laboratory (Ruiz and Chen, 2008) describes an approach that represents a major step ...
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