- Reduced local immunity in HPV-related VIN: Expression of chemokines and involvement of immunocompetent cells
[作者:Santegoets, LAM; van Seters, M; Heijmans-Antonissen, C; Kleinjan, A; van Beurden, M; Ewing, PC; Kuhne, LCM; Beckmann, I; Burger, CW; Helmerhorst, TJM; Blok, LJ,期刊:International Journal of Cancer, 页码:616-622 , 文章类型: Article,,卷期:2008年123-3]
- Usual type VIN is a premalignant disorder caused by persistent HPV infection. High prevalence of VIN in immuno-suppressed women suggests that a good innate and adaptive immune response is important for defense against HP...
- Tumour-mediated disruption of dendritic cell function: Inhibiting the MEK1/2-p44/42 axis restores IL-12 production and Th1-generation
[作者:Jackson, AM; Mulcahy, LA; Zhu, XW; O'Donnell, D; Patel, PM,期刊:International Journal of Cancer, 页码:623-632 , 文章类型: Article,,卷期:2008年123-3]
- Disfunctional dendritic cells (DC) are common in cancer patients; however, the underlying molecular targets are poorly understood. Nevertheless, adoptive-transfer and in situ vaccination protocols continue, largely witho...
- Haptoglobin-beta chain defined by monoclonal antibody RM2 as a novel serum marker for prostate cancer
[作者:Saito, S; Murayama, Y; Pan, Y; Taima, T; Fujimura, T; Murayama, K; Sadilek, M; Egawa, S; Ueno, S; Ito, A; Ishidoya, S; Nakagawa, H; Kato, M; Satoh, M; Endoh, M; Arai, Y,期刊:International Journal of Cancer, 页码:633-640 , 文章类型: Article,,卷期:2008年123-3]
- In our previous study, monoclonal antibody RM2, established toward the glycosyl epitope, reflected grade of malignancy of prostate cancer cells whereas RM2 reactivity to benign glands was negative or weak. RM2 reactivity...
- Expression and enzyme activity of alpha(1,6)fucosyltransferase in human colorectal cancer
[作者:Muinelo-Romay, L; Vazquez-Martin, C; Villar-Portela, S; Cuevas, E; Gil-Martin, E; Fernandez-Briera, A,期刊:International Journal of Cancer, 页码:641-646 , 文章类型: Article,,卷期:2008年123-3]
- Changes in enzyme activity and the expression levels of alpha(1,6)fucosyltransferase [alpha(1,6)FT] have been reported in certain types of malignant transformations. To develop a better understanding of the role of alpha...
- Mortality at 120 days after prostatic biopsy: A population-based study of 22,175 men
[作者:Gallina, A; Suardi, N; Montorsi, F; Capitanio, U; Jeldres, C; Saad, F; Graefen, M; Shariat, SF; Widmer, H; Arjane, P; Peloquin, F; Perrotte, P; Karakiewicz, PI,期刊:International Journal of Cancer, 页码:647-652 , 文章类型: Article,,卷期:2008年123-3]
- Trans-rectal ultrasound guided biopsy of the prostate represents the diagnostic standard for prostate cancer, but its mortality rate has never been examined. We performed a population-based study of 120-day mortality aft...
- Cancer of the mouth and pharynx, occupation and exposure to chemical agents in Finland [in 1971-95]
[作者:Tarvainen, L; Kyyronen, P; Kauppinen, T; Pukkala, E,期刊:International Journal of Cancer, 页码:653-659 , 文章类型: Article,,卷期:2008年123-3]
- The objective of this article was to find associations between cancer of the mouth and pharynx, occupation and chemical exposure. A cohort of Finns born between 1906 and 1945 was followed-up for 46.8 (21.5 in males and 2...
- Intake of flavonoids and risk of cancer in Finnish men: The Kuopio Ischaemic Heart Disease Risk Factor Study
[作者:Mursu, J; Nurmi, T; Tuomainen, TP; Salonen, JT; Pukkala, E; Voutilainen, S,期刊:International Journal of Cancer, 页码:660-663 , 文章类型: Article,,卷期:2008年123-3]
- Limited amount of evidence suggests that high intake of flavonoids could be associated with decreased risk of lung and colorectal cancer, but more studies are needed. In this prospective cohort study, we assessed the rel...
- Dietary flavonoid intake and risk of cancer in postmenopausal women: The Iowa Women's Health Study
[作者:Cutler, GJ; Nettleton, JA; Ross, JA; Harnack, LJ; Jacobs, DR; Scrafford, CG; Barraj, LM; Mink, PJ; Robien, K,期刊:International Journal of Cancer, 页码:664-671 , 文章类型: Article,,卷期:2008年123-3]
- Flavonoids, which are found in certain plant foods, are thought to lower cancer risk through their antioxidant, antiestrogenic and antiproliferative properties. We examined the association of intake of total flavonoids a...
- Predictors of ovarian cancer survival: A population-based prospective study in Sweden
[作者:Yang, L; Klint, A; Lambe, M; Bellocco, R; Riman, T; Bergfeldt, K; Persson, I; Weiderpass, E,期刊:International Journal of Cancer, 页码:672-679 , 文章类型: Article,,卷期:2008年123-3]
- Ovarian cancer is the leading cause of death from gynecologic malignancies among women worldwide. Little is known about reproductive factors or lifestyle determinants and ovarian cancer prognosis. The objective of this s...
- Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1
[作者:Murakami, M; Meneses, PI; Knight, JS; Lan, K; Kaul, R; Verma, SC; Robertson, ES,期刊:International Journal of Cancer, 页码:500-510 , 文章类型: Article,,卷期:2008年123-3]
- Cytoskeleton rearrangement is necessary for tumor invasion and metastasis. Cellular molecules whose role is to regulate components of the cytoskeletal structure can dictate changes in cellular morphology. One of these mo...
- Reduced tumor growth in a mouse model of schizophrenia, lacking the dopamine transporter
[作者:Asada, M; Ebihara, S; Numachi, Y; Okazaki, T; Yamanda, S; Ikeda, K; Yasuda, H; Sora, I; Arai, H,期刊:International Journal of Cancer, 页码:511-518 , 文章类型: Article,,卷期:2008年123-3]
- The incidence of cancer in patients with schizophrenia has been reported to be lower that in the general population. On the other hand, it is well established that patients with schizophrenia have a hyper-dopaminergic sy...
- Multiple B-vitamin inadequacy amplifies alterations induced by folate depletion in p53 expression and its downstream effector MDM2
[作者:Liu, ZH; Choi, SW; Crott, JW; Smith, DE; Mason, JB,期刊:International Journal of Cancer, 页码:519-525 , 文章类型: Article,,卷期:2008年123-3]
- Folate is required for biological methylation and nucleotide synthesis, aberrations of which are thought to be the mechanisms that enhance colorectal carcinogenesis produced by folate inadequacy. These functions of folat...
- Downregulation of osteopontin contributes to metastasis suppression by breast cancer metastasis suppressor 1
[作者:Hedley, BD; Welch, DR; Allan, AL; Al-Katib, W; Dales, DW; Postenka, CO; Casey, G; MacDonald, IC; Chambers, AF,期刊:International Journal of Cancer, 页码:526-534 , 文章类型: Article,,卷期:2008年123-3]
- Breast cancer metastasis suppressor 1 (BRMS1) inhibits the ability of multiple human and murine cancer cell lines to metastasize to lymph nodes, bones and lungs. Comparison of mRNA expression in metastatic MDA-MB-435 hum...
- DNA methylation and histone modifications cause silencing of Wnt antagonist gene in human renal cell carcinoma cell lines
[作者:Kawamoto, K; Hirata, H; Kikuno, N; Tanaka, Y; Nakagawa, M; Dahiya, R,期刊:International Journal of Cancer, 页码:535-542 , 文章类型: Article,,卷期:2008年123-3]
- Secreted frizzled-related protein 2 (sFRP2) is a negative modulator of the Wingless-type (Wnt) signaling pathway, and shown to be inactivated in renal cell carcinoma (RCC). However, the molecular mechanism of silencing o...
- Aberrant expression of Cks1 and Cks2 contributes to prostate tumorigenesis by promoting proliferation and inhibiting programmed cell death
[作者:Lan, YS; Zhang, YY; Wang, JH; Lin, CH; Ittmann, MM; Wang, F,期刊:International Journal of Cancer, 页码:543-551 , 文章类型: Article,,卷期:2008年123-3]
- The mammalian Cks family consists of 2 well-conserved small proteins, Cks1 and Cks2. Cks1 has been shown to promote cell-cycle progression by triggering degradation of p27(kip1). The function of Cks2 in somatic mammalian...
- Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells
[作者:Kikuno, N; Shiina, H; Urakami, S; Kawamoto, K; Hirata, H; Tanaka, Y; Majid, S; Igawa, M; Dahiya, R,期刊:International Journal of Cancer, 页码:552-560 , 文章类型: Article,,卷期:2008年123-3]
- Genistein is a phytoestrogen that has been reported to suppress the AKT signaling pathway in several malignancies. However, the molecular mechanism of genistein action is not known. We tested the hypothesis that genistei...
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