- The Ikaros splice isoform, Ikaros 6, immortalizes murine haematopoietic progenitor cells
[作者：Ruiz, A; Williams, O; Brady, HJM,期刊：International Journal of Cancer, 页码：1240-1245 , 文章类型： Article，,卷期：2008年123-6]
- Alternative pre-mRNA splicing is emerging as a major control point in both the initiation and progression of tumourigenesis. Overexpression of the dominant negative Ikaros splice isoform, Ik6, is found in many human canc...
- Catecholestrogens induce oxidative stress and malignant transformation in human endometrial glandular cells: Protective effect of catechol-O-methyltransferase
[作者：Salama, SA; Kamel, M; Awad, M; Ben Nasser, AH; Al-Hendy, A; Botting, S; Arrastia, C,期刊：International Journal of Cancer, 页码：1246-1254 , 文章类型： Article，,卷期：2008年123-6]
- Prolonged exposure to unopposed estrogens is a major risk factor for the development of endometrial cancer. Oxidative metabolism of estradiol (E,) into the catecholestrogens (CEs), 4-hydroxyestradiol (4-OHE2) and 2-hydro...
- Sulforaphane inhibited expression of hypoxia-inducible factor-1 alpha in human tongue squamous cancer cells and prostate cancer cells
[作者：Yao, H; Wang, HM; Zhang, Z; Jiang, BH; Luo, J; Shi, XL,期刊：International Journal of Cancer, 页码：1255-1261 , 文章类型： Article，,卷期：2008年123-6]
- Previous studies show that a number of natural compounds from our diet have anticancer effects. Sulforaphane is the most characterized isothiocyanates (ITCs), which are identified in cruciferous vegetables. Sulforaphane ...
- Enzymatic metabolites of lycopene induce Nrf2-mediated expression of phase II detoxifying/antioxidant enzymes in human bronchial epithelial cells
[作者：Lian, FZ; Wang, XD,期刊：International Journal of Cancer, 页码：1262-1268 , 文章类型： Article，,卷期：2008年123-6]
- Lycopene can be cleaved by carotene 9',10'-oxygenase at its 9',10' double bond to form apo-10'-lycopenoids, including apo-10'-lycopenal, -lycopenol and -lycopenoic acid. The latter has been recently shown to inhibit lung...
- Inhibition of heme oxygenase 1 expression by small interfering RNA decreases orthotopic tumor growth in livers of mice
[作者：Sass, G; Leukel, P; Schmitz, V; Raskopf, E; Ocker, M; Neureiter, D; Meissnitzer, M; Tasika, E; Tannapfel, A; Tiegs, G,期刊：International Journal of Cancer, 页码：1269-1277 , 文章类型： Article，,卷期：2008年123-6]
- Endogenous overexpression of the antiapoptotic protein heme oxygenase 1 (HO-1) has been shown to occur in various cancer diseases and might contribute to cancer progression. We compared the expression levels of HO-1 in h...
- Geographic variation of gallbladder cancer mortality and risk factors in Chile: A population-based ecologic study
[作者：Andia, ME; Hsing, AW; Andreotti, G; Ferreccio, C,期刊：International Journal of Cancer, 页码：1411-1416 , 文章类型： Article，,卷期：2008年123-6]
- Chile's gallbladder cancer rates are among the highest in the world, being the leading cause of cancer deaths among Chilean women. To provide insights into the etiology of gallbladder cancer, we conducted an ecologic stu...
- Trends in esophageal cancer incidence by histology, United States, 1998-2003
[作者：Trivers, KF; Sabatino, SA; Stewart, SL,期刊：International Journal of Cancer, 页码：1422-1428 , 文章类型： Article，,卷期：2008年123-6]
- Esophageal adenocarcinoma rates may be increasing, whereas, squamous cell carcinoma rates appear to be decreasing in the United States. Previous population-based research on esophageal cancer has only covered up to 68% o...
- Family history of cancer and stomach cancer risk
[作者：Foschi, R; Lucenteforte, E; Bosetti, C; Bertuccio, P; Tavani, A; La Vecchia, C; Negri, E,期刊：International Journal of Cancer, 页码：1429-1432 , 文章类型： Article，,卷期：2008年123-6]
- A family history of stomach cancer in first-degree relatives increases the risk of stomach cancer, but uncertainties remain as concerns the variation of (fie risk according to age, sex and type of relative, as well as on...
- Nuclear karyopherin alpha 2 expression predicts poor survival in patients with advanced breast cancer irrespective of treatment intensity
[作者：Gluz, O; Wild, P; Meiler, R; Diallo-Danebrock, R; Ting, E; Mohrmann, S; Schuett, G; Dahl, E; Fuchs, T; Herr, A; Gaumann, A; Frick, M; Porernba, C; Nitz, UA; Hartmann, A,期刊：International Journal of Cancer, 页码：1433-1438 , 文章类型： Article，,卷期：2008年123-6]
- Intensive lymph node involvement indicates poor prognosis in breast cancer patients. The significance of other molecular prognostic factors in this subgroup is unclear. Karyopherin alpha 2 (KPNA2) has been reported as an...
- Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway
[作者：Cheng, YJ; Lee, CH; Lin, YP; Huang, JY; Su, CC; Chang, WT; Yang, BC,期刊：International Journal of Cancer, 页码：1278-1285 , 文章类型： Article，,卷期：2008年123-6]
- Caspase-3 is known as a cysteine protease that primarily executes the cell death program. However, some tumors express higher levels of caspase-3 in positive correlation with malignancy. Here, we showed that caspase-3 ca...
- Systemic IGF-I administration stimulates the in vivo growth of early, but not advanced, renal cell carcinoma
[作者：Rosendahl, AH; Holly, JMP; Celander, M; Forsberg, G,期刊：International Journal of Cancer, 页码：1286-1291 , 文章类型： Article，,卷期：2008年123-6]
- Insulin-like growth factor I (IGF-I) is a potent mitogen and antiapoptotic factor. Although elevated serum IGF-I levels have been associated with increased cancer risk, it is not yet clear whether IGF-I sensitivity is su...
- Molecular evidence for a clonal relationship between multiple lesions in patients with unknown primary adenocarcinoma
[作者：Speel, EJM; de Wouw, ALV; Claessen, SMH; Haesevoets, A; Hopman, AHN; van der Wurff, AAM; Osieka, R; Buettner, R; Hillen, HFP; Ramaekers, FCS,期刊：International Journal of Cancer, 页码：1292-1300 , 文章类型： Article，,卷期：2008年123-6]
- Unknown primary adenocarcinoma (UPA) comprises a group of heterogeneous cancers of great clinical and biological interest. UPA presents as metastatic disease without a detectable primary site after medical workup. Here w...
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