- Enhanced anti-cancer effect of a phosphatidylinositol-3 kinase inhibitor and doxorubicin on human breast epithelial cell lines with different p53 and oestrogen receptor status
[作者：Wang, YA; Johnson, SK; Brown, BL; McCarragher, LM; A-Sakkaf, K; Royds, JA; Dobson, PRM,期刊：International Journal of Cancer, 页码：1536-1544 , 文章类型： Article，,卷期：2008年123-7]
- New efforts are being focused on signalling pathways as targets for cancer therapy. This particular study was designed to investigate whether blockade of the phosphatidylinositol 3OH-kinase (PI3K) pathway (a survival/ant...
- The enhancer of zeste homolog 2 gene contributes to cell proliferation and apoptosis resistance in renal cell carcinoma cells
[作者：Wagener, N; Holland, D; Bulkescher, J; Crnkovic-Mertens, T; Hoppe-Seyler, K; Zentgraf, H; Pritsch, M; Buse, S; Pfitzenmaier, J; Haferkamp, A; Hohenfellner, M; Hoppe-Seyler, F,期刊：International Journal of Cancer, 页码：1545-1550 , 文章类型： Article，,卷期：2008年123-7]
- The enhancer of zeste homolog 2 (EZH2) gene has been recently linked to human malignancies where it may serve as a new target for cancer therapy. Here, we analyzed EZH2 expression in primary renal cell carcinoma (RCC) sp...
- Cancer testis antigen expression in gastrointestinal stromal tumors: New markers for early recurrence
[作者：Perez, D; Herrmann, T; Jungbluth, AA; Samartzis, P; Spagnoli, G; Demartines, N; Clavien, PA; Marino, S; Seifert, B; Jaeger, D,期刊：International Journal of Cancer, 页码：1551-1555 , 文章类型： Article，,卷期：2008年123-7]
- Cancer testis antigens (CTAs) are expressed in a variety of malignant tumors but not in any normal adult tissues except germ cells and occasionally placenta. Because of this tumor-associated pattern of expression, CTAs a...
- Molecular characteristics and predictors of survival in patients with malignant neuroendocrine tumors
[作者：Arnold, CN; Nagasaka, T; Goel, A; Scharf, I; Grabowski, P; Sosnowski, A; Schmitt-Graff, A; Boland, CR; Arnold, R; Blum, HE,期刊：International Journal of Cancer, 页码：1556-1564 , 文章类型： Article，,卷期：2008年123-7]
- To better understand the molecular pathogenesis of neuroendocrine tumors (NET), we investigated the molecular and clinical characteristics of malignant poorly differentiated colorectal NET and compared these findings wit...
- Identification of truncated chemokine receptor 7 in human colorectal cancer unable to localize to the cell surface and unreactive to external ligands
[作者：Na, IK; Busse, A; Scheibenbogen, C; Ghadjar, P; Coupland, SE; Letsch, A; Loddenkemper, C; Stroux, A; Bauer, S; Thiel, E; Keilholz, U,期刊：International Journal of Cancer, 页码：1565-1572 , 文章类型： Article，,卷期：2008年123-7]
- Chemokine receptors are thought to be involved in the process of cancer metastases. When investigating cell lines and tissues from colorectal cancer (CRC), the CCR7 protein unexpectedly was confined to the cytoplasm and ...
- Chemoprevention of glandular stomach carcinogenesis through duodenogastric reflux in rats by a COX-2 inhibitor
[作者：Oba, M; Miwa, K; Fujimura, T; Harada, S; Sasaki, S; Hattori, T,期刊：International Journal of Cancer, 页码：1491-1498 , 文章类型： Article，,卷期：2008年123-7]
- Duodenogastric reflux (DGR) causes glandular stomach carcinogenesis in rats without carcinogens. We aimed to investigate how this carcinogenesis might be prevented by a selective COX-2 inhibitor, meloxicam. A series of 1...
- Racial/ethnic variation in EBV-positive classical Hodgkin lymphoma in California populations
[作者：Glaser, SL; Gulley, ML; Clarke, CA; Keegan, TH; Chang, ET; Shema, SJ; Craig, FE; DiGiuseppe, JA; Dorfman, RF; Mann, RB; Anton-Culver, H; Ambinder, RF,期刊：International Journal of Cancer, 页码：1499-1507 , 文章类型： Article，,卷期：2008年123-7]
- Epstein-Barr virus (EBV) is detected in the tumor cells of some but not all Hodgkin lymphoma (HL) patients, and evidence indicates that EBV-positive and -negative HL are distinct entities. Racial/ethnic variation in EBV-...
- Inhibition of epidermal growth factor receptor signaling pathway by delphinidin, an anthocyanidin in pigmented fruits and vegetables
[作者：Afaq, F; Zaman, N; Khan, N; Syed, DN; Sarfaraz, S; Abu Zaid, M; Mukbtar, H,期刊：International Journal of Cancer, 页码：1508-1515 , 文章类型： Article，,卷期：2008年123-7]
- Inhibitors of the epidermal growth factor receptor (EGFR) have generated considerable hope for cancer treatment, specifically for lung and breast cancers. Therefore, identification of a natural, nontoxic agent(s) as an i...
- SV40 large T antigen-transformed human primary normal and cancerous mammary epithelial cells are phenotypically similar but can be distinguished in 3D culture with selection medium
[作者：Li, LP; Willimsky, G; Seitz, S; Xu, YX; Li, YP; Schwarz, LE; Schlag, PM; Blankenstein, T,期刊：International Journal of Cancer, 页码：1516-1525 , 文章类型： Article，,卷期：2008年123-7]
- Human normal mammary epithelial cells (NMECs) have 2 major in vitro growth restrictions, senescence and crisis. Cellular immortalization is considered a hallmark of malignancy. However, cancerous mammary epithelial cells...
- Rationale for folate receptor alpha targeted therapy in "high risk" endometrial carcinomas
[作者：Jones, MB; Neuper, C; Clayton, A; Mariani, A; Konecy, G; Thomas, MB; Keeney, G; Hartmann, L; Podratz, KC,期刊：International Journal of Cancer, 页码：1699-1703 , 文章类型： Article，,卷期：2008年123-7]
- Advanced and recurrent endometrial cancers account for the majority of deaths from this disease with limited therapeutic options. High grade, and nonendometrioid histology, pathologically characterize the endometrial tum...
- Replication competent Semliki Forest virus prolongs survival in experimental lung cancer
[作者：Maatta, AM; Makinen, K; Ketola, A; Liimatainen, T; Yongabi, FN; Vaha-Koskela, M; Pirinen, R; Rautsi, O; Pellinen, R; Hinkkanen, A; Wahlfors, J,期刊：International Journal of Cancer, 页码：1704-1711 , 文章类型： Article，,卷期：2008年123-7]
- We evaluated the therapeutic potential of the replication competent vector VA7-EGFP, which is based on the avirulent Semliki Forest virus (SFV) strain A7 (74) carrying the EGFP marker gene in an orthotopic lung cancer tu...
- Folate deprivation induces BCRP (ABCG2) expression and mitoxantrone resistance in Caco-2 cells
[作者：Lemos, C; Kathmann, I; Giovannetti, E; Dekker, H; Scheffer, GL; Calhau, C; Jansen, G; Peters, GJ,期刊：International Journal of Cancer, 页码：1712-1720 , 文章类型： Article，,卷期：2008年123-7]
- Folates can induce the expression and activity of the breast-cancer- resistance-protein (BCRP) and the multidrug-resistance-protein-1 (MRP1). Our aim was to study the time-dependent effect of folate deprivation/supplemen...
- The mitotic checkpoint gene, SIL is regulated by E2F1
[作者：Erez, A; Chaussepied, M; Castiel, A; Colaizzo-Anas, T; Aplan, PD; Ginsberg, D; Izraeli, S,期刊：International Journal of Cancer, 页码：1721-1725 , 文章类型： Article，,卷期：2008年123-7]
- The SIL gene expression is increased in multiple cancers and correlates with the expression of mitotic spindle checkpoint genes and with increased metastatic potential. SIL regulates mitotic entry, organization of the mi...
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