- Acquired cisplatin resistance in the head-neck cancer cell line Cal27 is associated with decreased DKK1 expression and can partially be reversed by overexpression of DKK1
[作者:Gosepath, EM; Eckstein, N; Hamacher, A; Servan, K; von Jonquieres, G; Lage, H; Gyorffy, B; Royer, HD; Kassack, MU,期刊:International Journal of Cancer, 页码:2013-2019 , 文章类型: Article,,卷期:2008年123-9]
- Head and neck cancers are treated by a combination of surgery, radiotherapy and/or chemotherapy. The clinical success of cisplatin-based chemotherapy, mostly in combination with 5-FU or a taxane, is however limited by mu...
- Chemotherapeutic drugs and human tumor cells cytokine network
[作者:Levina, V; Su, YY; Nolen, B; Liu, XN; Gordin, Y; Lee, M; Lokshin, A; Gorelik, E,期刊:International Journal of Cancer, 页码:2031-2040 , 文章类型: Article,,卷期:2008年123-9]
- The ability of human tumor cell lines to produce various cytokines, chemokines, angiogenic and growth factors was investigated using Luminex multiplex technology. Media conditioned by tumor cells protected tumor cells fr...
- Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse model
[作者:Miao, JY; Mu, D; Ergel, B; Singavarapu, R; Duan, ZF; Powers, S; Oliva, E; Orsulic, S,期刊:International Journal of Cancer, 页码:2041-2047 , 文章类型: Article,,卷期:2008年123-9]
- Hepsin is a serine protease that is widely expressed in different tissues and cell types, most prominently in the normal liver and kidney. Overexpression of hepsin has been associated with prostate cancers, ovarian cance...
- Prevalence, incidence and clearance of human papillomavirus infection among young primiparous pregnant women in Kampala, Uganda
[作者:Banura, C; Franceschi, S; van Doorn, LJ; Arslan, A; Kleter, B; Wabwire-Mangen, F; Mbidde, EK; Quint, W; Weiderpass, E,期刊:International Journal of Cancer, 页码:2180-2187 , 文章类型: Article,,卷期:2008年123-9]
- The proportion of women who have already been exposed to human papillomavirus (HPV) infection by the time they first become pregnant, and the influence of pregnancy and delivery on the course of HPV infection are unclear...
- Loss of Drop1 expression already at early tumor stages in a wide range of human carcinomas
[作者:Marme, A; Zimmermann, HP; Moldenhauer, G; Schorpp-Kistner, M; Muller, C; Keberlein, O; Giersch, A; Kretschmer, J; Seib, B; Spiess, E; Hunziker, A; Merchan, F; Moller, P; Hahn, U; Kurek, R; Marme, F; Bastert, G; Wallwiener, D; Ponstingl, H,期刊:International Journal of Cancer, 页码:2048-2056 , 文章类型: Article,,卷期:2008年123-9]
- In a study on gene deregulation in ovarian carcinoma we found a mRNA ceding for a 350 kDa protein, Drop1, to be downregulated 20- to 180-fold in the majority of ovarian and mammary carcinomas. The mRNA is encoded by a se...
- Ras-driven proliferation and apoptosis signaling during rat liver carcinogenesis is under genetic control
[作者:Calvisi, DF; Pinna, F; Pellegrino, R; Sanna, V; Sini, M; Daino, L; Simile, MM; De Miglio, MR; Frau, M; Tomasi, ML; Seddaiu, MA; Muroni, MR; Feo, F; Pascale, RM,期刊:International Journal of Cancer, 页码:2057-2064 , 文章类型: Article,,卷期:2008年123-9]
- Fast growth and deregulation of G1 and S phases characterize preneoplastic and neoplastic liver lesions of genetically susceptible F344 rats, whereas a G1-S block in lesions of resistant BN rats explains their low progre...
- Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia
[作者:Kazemi, T; Asgarian-Omran, H; Hojjat-Farsangi, M; Shabani, M; Memarian, A; Sharifian, RA; Razavi, SM; Jeddi-Tehrani, M; Rabbani, H; Shokri, F,期刊:International Journal of Cancer, 页码:2113-2119 , 文章类型: Article,,卷期:2008年123-9]
- Fc receptor-like (FCRL) 1-5 molecules are exclusively expressed in B-cells and have recently been considered as potential targets for immunotherapy of B-cell malignancies. In this study, the expression pattern of FCRL1-5...
- Effect of obesity and other lifestyle factors on mortality in women with breast cancer
[作者:Dal Maso, L; Zucchetto, A; Talamini, R; Serraino, D; Stocco, CF; Vercelli, M; Falcini, F; Franceschi, S,期刊:International Journal of Cancer, 页码:2188-2194 , 文章类型: Article,,卷期:2008年123-9]
- A few lifestyle characteristics before cancer diagnosis have been suggested to modify the prognosis of breast cancer. Follow-up information from 1,453 women with incident invasive breast cancer, diagnosed between 1991 an...
- Angiostatic activity of obtustatin as alpha 1 beta 1 integrin inhibitor in experimental melanoma growth
[作者:Brown, MC; Staniszewska, I; Del Valle, L; Tuszynski, GP; Marcinkiewicz, C,期刊:International Journal of Cancer, 页码:2195-2203 , 文章类型: Article,,卷期:2008年123-9]
- The presented results show the effect of targeting of collagen receptor, alpha 1 beta 1 integrin expressed on the endothelial cells on the development of experimental melanoma and pathological angiogenesis. Obtustatin, a...
- Lactotransferrin: A candidate tumor suppressor - Deficient expression in human nasopharyngeal carcinoma and inhibition of NPC cell proliferation by modulating the mitogen-activated protein kinase pathway
[作者:Zhou, YH; Zeng, ZY; Zhang, WL; Xiong, W; Wu, MH; Tan, YX; Yi, W; Xiao, L; Li, XL; Huang, C; Cao, L; Tang, K; Li, XY; Shen, SR; Li, GY,期刊:International Journal of Cancer, 页码:2065-2072 , 文章类型: Article,,卷期:2008年123-9]
- Lactotransferrin (LTF) has been shown to regulate tumorogenesis. However, little is known about the role of LTF in regulating the development of human nasopharyngeal carcinoma (NPC). The aim of our study was to investiga...
- Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy
[作者:Naschberger, E; Croner, RS; Merkel, S; Dimmler, A; Tripal, P; Amann, KU; Kremmer, E; Brueckl, WM; Papadopoulos, T; Hohenadl, C; Hohenberger, W; Sturzl, M,期刊:International Journal of Cancer, 页码:2120-2129 , 文章类型: Article,,卷期:2008年123-9]
- Angiogenesis and inflammation are the 2 major stroma reactions in colorectal carcinoma (CRC). Guanylate binding protein-1 (GBP-1) is a key mediator of angiostatic effects of inflammation. Therefore, we hypothesized that ...
- Four potential biomarkers as prognostic factors in stage III serous ovarian adenocarcinomas
[作者:Partheen, K; Levan, K; Osterberg, L; Claesson, I; Fallenius, G; Sundfeldt, K; Horvath, G,期刊:International Journal of Cancer, 页码:2130-2137 , 文章类型: Article,,卷期:2008年123-9]
- The mortality rate for patients with ovarian carcinomas is high and the available prognostic factors are insufficient. The use of biomarkers may contribute to better prediction and survival for these patients. We aimed t...
- Ebselen sensitizes glioblastoma cells to Tumor Necrosis Factor (TNF alpha)-induced apoptosis through two distinct pathways involving NF-kappa B downregulation and Fas-mediated formation of death inducing signaling complex
[作者:Sharma, V; Tewari, R; Sk, UH; Joseph, C; Sen, E,期刊:International Journal of Cancer, 页码:2204-2212 , 文章类型: Article,,卷期:2008年123-9]
- Resistance to tumor necrosis factor (TNF alpha)-induced apoptosis in various cancer cells has been attributed to the activation of the transcription factor NF-kappa B. Ebselen (2-phenyl-1,2-benzisoselenazol-3[2H]one)-a s...
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