- Effect of the cyclic stretch on the expression of osteogenesis genes in human periodontal ligament cells
[作者：Liu, MY; Dai, J; Lin, Y; Yang, L; Dong, H; Li, YM; Ding, Y; Duan, YZ,期刊：Gene, 页码：187-193 , 文章类型： Article，,卷期：2012年491-2]
- Periodontal ligament cells can potentially differentiate into osteoblast-like cells and influence the remodeling of periodontal tissues under mechanical strain conditions. In the present study, Gene chip technology was a...
- Comparative analysis of hemagglutinin of 2009 H1N1 influenza A pandemic indicates its evolution to 1918 H1N1 pandemic
[作者：Masoodi, TA; Shaik, NA; Shafi, G; Munshi, A; Ahamed, AK; Masoodi, ZA,期刊：Gene, 页码：200-204 , 文章类型： Article，,卷期：2012年491-2]
- To gain insight into the possible origin of the hemagglutinin of 2009 outbreak, we performed its comparative analysis with hemagglutinin of influenza viral strains from 2005 to 2008 and the past pandemics of 1977, 1968, ...
- Self-assemble gene delivery system for molecular targeting using nucleic acid aptamer
[作者：Kurosaki, T; Higuchi, N; Kawakami, S; Higuchi, Y; Nakamura, T; Kitahara, T; Hashida, M; Sasaki, H,期刊：Gene, 页码：205-209 , 文章类型： Article，,卷期：2012年491-2]
- We have developed a novel vector constructed with pDNA, polyethylenimine (PEI), and mucin 1 (MUC1) aptamer for tumor-targeted gene delivery. The MUC1 aptamer and non-specific aptamer were employed to coat the pDNA/PEI co...
- In silico and in vivo identification of the intermediate filament vimentin that is downregulated downstream of Brachyury during Xenopus embryogenesis
[作者：Yamada, A; Koyanagi, KO; Watanabe, H,期刊：Gene, 页码：232-236 , 文章类型： Article，,卷期：2012年491-2]
- Brachyury, a member of the T-box transcription family, has been suggested to be essential for morphogenetic movements in various processes of animal development. However, little is known about its critical transcriptiona...
- Analysis of the association between transcription factor binding site variants and distinct accompanying regulatory motifs in yeast
[作者：Chiang, SF; Swamy, KBS; Hsu, TW; Tsai, ZTY; Lu, HHS; Wang, DY; Tsai, HK,期刊：Gene, 页码：237-245 , 文章类型： Article，,卷期：2012年491-2]
- It is generally accepted that genes are regulated by the interactions between transcription factors (TFs) and their binding sites (TFBSs). Some studies have demonstrated that nucleotide variants at variable positions in ...
- Mutation p.Leu354Pro in EDA causes severe hypohidrotic ectodermal dysplasia in a Chinese family
[作者：Liu, Y; Yu, XY; Wang, L; Li, C; Archacki, S; Huang, CZ; Liu, JY; Wang, Q; Liu, MG; Tang, ZH,期刊：Gene, 页码：246-250 , 文章类型： Article，,卷期：2012年491-2]
- X-linked recessive hypohidrotic ectodermal dysplasia (XLHED) is characterized by the defective morphogenesis of teeth, hair, and eccrine sweat glands. It is associated with mutations in the EDA gene. Up to now, more than...
- The associations of IL-18 serum levels and promoter polymorphism with tacrolimus pharmacokinetics and hepatic allograft dysfunction in Chinese liver transplantation recipients
[作者：Li, Y; Zou, YG; Cai, B; Yang, B; Ying, BW; Shi, YY; Wang, LL,期刊：Gene, 页码：251-255 , 文章类型： Article，,卷期：2012年491-2]
- Interleukin 18 (IL-18) is a potent proinflammatory cytokine, which promotes the secretions of TNF-alpha, IL-1 beta, IL-2 and IFN-gamma. All those inflammatory cytokines can influence the CYP450 and MDR dependent drug dis...
- Cloning and polymorphism analysis of prion protein gene in domestic bactrian camel in China
[作者：Xu, LH; Zhang, ZM; Wang, L; Feng, DZ; Zhou, XM; Xu, BR; Zhao, DM,期刊：Gene, 页码：256-259 , 文章类型： Article，,卷期：2012年491-2]
- Up to now, little is known about the prion protein gene (PRNP) of domestic bactrian camels, and no polymorphisms of the bactrian camel PRNP have been analyzed or reported. In this study, we cloned and analyzed the PRNP s...
- The relative contribution of environmental and genetic factors to phenotypic variation in familial Mediterranean fever (FMF)
[作者：Ben-Zvi, I; Brandt, B; Berkun, Y; Lidar, M; Livneh, A,期刊：Gene, 页码：260-263 , 文章类型： Article，,卷期：2012年491-2]
- Introduction: Familial Mediterranean fever (FMF) is an autosomal recessive disease, caused by mutations in the FMF gene MEFV (MEditerranean FeVer). It has a large phenotypic diversity even in patients with similar genoty...
- Engineering of a metagenome derived lipase toward thermal tolerance: Effect of asparagine to lysine mutation on the protein surface
[作者：Sharma, PK; Kumar, R; Kumar, R; Mohammad, O; Singh, R; Kaur, J,期刊：Gene, 页码：264-271 , 文章类型： Article，,卷期：2012年491-2]
- A highly thermostable mutant lipase was generated and characterized. Mutant enzyme demonstrated 144 fold enhanced thermostability over the wild type enzyme at 60 degrees C. Interestingly, the overall catalytic efficiency...
- Effects of egt gene transfer on the development of Bombyx mori
[作者：Zhang, X; Xue, RY; Cao, GL; Hu, XL; Wang, XJ; Pan, ZH; Xie, M; Yu, XH; Gong, CL,期刊：Gene, 页码：272-277 , 文章类型： Article，,卷期：2012年491-2]
- This study investigated the effects of gain of ecdysteroid UDP-glucosyltransferase (EGT) gene function mutation on the development of the silkworm. Bombyx mori. A novel piggyBac-derived plasmid containing the egt gene fr...
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