- Prospective Study Reveals Associations Between Colorectal Cancer and Type 2 Diabetes Mellitus or Insulin Use in Men
[作者:Campbell, PT; Deka, A; Jacobs, EJ; Newton, CC; Hildebrand, JS; McCullough, ML; Limburg, PJ; Gapstur, SM,期刊:Gastroenterology, 页码:1138-1146 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: Type 2 diabetes mellitus (DM) is associated with an increased risk of colorectal cancer (CRC); it is not clear if this association varies by sex or other factors. Insulin use might also be associated w...
- The Reduction in Colorectal Cancer Mortality After Colonoscopy Varies by Site of the Cancer
[作者:Singh, H; Nugent, Z; Demers, AA; Kliewer, EV; Mahmud, SM; Bernstein, CN,期刊:Gastroenterology, 页码:1128-1137 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: There are limited data on mortality from colorectal cancer (CRC) among patients who have received colonoscopy examinations. We sought to determine CRC mortality among persons undergoing colonoscopies c...
- Prolonged Episodes of Acute Diarrhea Reduce Growth and Increase Risk of Persistent Diarrhea in Children
[作者:Moore, SR; Lima, NL; Soares, AM; Oria, RB; Pinkerton, RC; Barrett, LJ; Guerrant, RL; Lima, AAM,期刊:Gastroenterology, 页码:1156-1164 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: Prolonged episodes of acute diarrhea (ProD; duration 7-13 days) or persistent diarrhea (PD; duration >= 14 days) are important causes of undernutrition, yet the epidemiology and nutritional impact of P...
- Risk Factors Associated With Progression to Intestinal Complications of Crohn's Disease in a Population-Based Cohort
[作者:Thia, KT; Sandborn, WJ; Harmsen, WS; Zinsmeister, AR; Loftus, EV,期刊:Gastroenterology, 页码:1147-1155 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND AND AIMS: We sought to assess the evolution of Crohn's disease behavior in an American population-based cohort. METHODS: Medical records of all Olmsted County, Minnesota residents who were diagnosed with Crohn...
- Histamine(2)-Receptor Antagonists Are an Alternative to Proton Pump Inhibitor in Patients Receiving Clopidogrel
[作者:Wu, CY; Chan, FKL; Wu, MS; Kuo, KN; Wang, CB; Tsao, CR; Lin, JT,期刊:Gastroenterology, 页码:1165-1165 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: Previous observational studies reported that concomitant use of clopidogrel and proton pump inhibitors (PPIs) in patients with prior acute coronary syndrome (ACS) was associated with adverse cardiovasc...
- Acute HIV Infection Induces Mucosal Infiltration With CD4+and CD8+T Cells, Epithelial Apoptosis, and a Mucosal Barrier Defect
[作者:Epple, HJ; Allers, K; Troger, H; Kuhl, A; Erben, U; Fromm, M; Zeitz, M; Loddenkemper, C; Schulzke, JD; Schneider, T,期刊:Gastroenterology, 页码:1289-1289 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: A barrier defect of the intestinal mucosa is thought to affect the progression of human immunodeficiency virus (HIV) infection. It is not clear whether the mucosal barrier impairment already is present...
- Interleukin-11 Reduces TLR4-Induced Colitis in TLR2-Deficient Mice and Restores Intestinal STAT3 Signaling
[作者:Gibson, DL; Montero, M; Ropeleski, MJ; Bergstrom, KSB; Ma, CX; Ghosh, S; Merkens, H; Huang, JT; Mansson, LE; Sham, HP; McNagny, KM; Vallance, BA,期刊:Gastroenterology, 页码:1277-1288 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: The roles of intestinal Toll-like receptors (TLR) in the pathogenesis of colitis are not known. TLR2 and TLR4 appear to protect against dextran sodium sulfate-induced colitis by promoting mucosal integ...
- Phospho-Sulindac (OXT-328), a Novel Sulindac Derivative, Is Safe and Effective in Colon Cancer Prevention in Mice
[作者:Mackenzie, GG; Sun, Y; Huang, LQ; Xie, GA; Ouyang, N; Gupta, RC; Johnson, F; Komninou, D; Kopelovich, L; Rigas, B,期刊:Gastroenterology, 页码:1320-1332 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective cancer chemopreventive agents. However, chronic administration of NSAIDs is associated with significant side effects, mainly of the gastroint...
- In the Absence of HCV Infection, Interferon Stimulated Gene Expression in Liver Is Not Associated With IL28B Genotype
[作者:Shebl, FM; Maeder, D; Shao, YW; Prokunina-Olsson, L; Schadt, EE; O'Brien, TR,期刊:Gastroenterology, 页码:1422-1424 , 文章类型: Letter,,卷期:2010年139-4]
-
- Patients With Irritable Bowel Syndrome Have Altered Emotional Modulation of Neural Responses to Visceral Stimuli
[作者:Elsenbruch, S; Rosenberger, C; Bingel, U; Forsting, M; Schedlowski, M; Gizewski, ER,期刊:Gastroenterology, 页码:1310-1310 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: In patients with irritable bowel syndrome (IBS), pain amplification and hypervigilance might result from altered affective-motivational modulation of the pain response. We investigated the effects of e...
- Loss of Lsc/p115 Protein Leads to Neuronal Hypoplasia in the Esophagus and an Achalasia-Like Phenotype in Mice
[作者:Zizer, E; Beilke, S; Bauerle, T; Schilling, K; Mohnle, U; Adler, G; Fischer, KD; Wagner, M,期刊:Gastroenterology, 页码:1344-1354 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: Lsc/p115 originally was described as hematopoietic Ras homologous protein guanine exchange factor (Rho-GEF) regulating leukocyte migration, adhesion, and marginal zone B-cell homeostasis. Here we inves...
- Variants in the ITPA Gene Protect Against Ribavirin-Induced Hemolytic Anemia and Decrease the Need for Ribavirin Dose Reduction
[作者:Thompson, AJ; Fellay, J; Patel, K; Tillmann, HL; Naggie, S; Ge, DL; Urban, TJ; Shianna, KV; Muir, AJ; Fried, MW; Afdhal, NH; Goldstein, DB; Mchutchison, JG,期刊:Gastroenterology, 页码:1181-1181 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: In a genome-wide association study of patients being treated for chronic hepatitis C, 2 functional variants in ITPA that cause inosine triphosphatase (ITPase) deficiency were shown to protect against r...
- Tenofovir Is Effective Alone or With Emtricitabine in Adefovir-Treated Patients With Chronic-Hepatitis B Virus Infection
[作者:Berg, T; Marcellin, P; Zoulim, F; Moller, B; Trinh, H; Chan, S; Suarez, E; Lavocat, F; Snow-Lampart, A; Frederick, D; Sorbel, J; Borroto-Esoda, K; Oldach, D; Rousseau, F,期刊:Gastroenterology, 页码:1207-1207 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: We compared treatments for patients with chronic hepatitis B virus (HBV) infection who had an incomplete response to adefovir dipivoxil (ADV). We evaluated a combination of fixed-dose emtricitabine (FT...
- Infections in Patients With Cirrhosis Increase Mortality Four-Fold and Should Be Used in Determining Prognosis
[作者:Arvaniti, V; D'Amico, G; Fede, G; Manousou, P; Tsochatzis, E; Pleguezuelo, M; Burroughs, AK,期刊:Gastroenterology, 页码:1246-1246 , 文章类型: Article,,卷期:2010年139-4]
- BACKGROUND & AIMS: A staged prognostic model of cirrhosis based on varices, ascites, and bleeding has been proposed. We analyzed data on infections in patients with cirrhosis to determine whether it is also a prognostic ...
|