- Determinants of Changes in Linear Growth and Body Composition in Incident Pediatric Crohn's Disease
[作者:Thayu, M; Denson, LA; Shults, J; Zemel, BS; Burnham, JM; Baldassano, RN; Howard, KM; Ryan, A; Leonard, MB,期刊:Gastroenterology, 页码:430-438 , 文章类型: Article,,卷期:2010年139-2]
- BACKGROUND & AIMS: Pediatric Crohn's disease (CD) is associated with growth, lean mass (LM), and fat mass (FM) deficits. This study assessed and identified determinants of changes in height and body composition in childr...
- Effects of Lesogaberan on Reflux and Lower Esophageal Sphincter Function in Patients With Gastroesophageal Reflux Disease
[作者:Boeckxstaens, GE; Beaumont, H; Mertens, V; Denison, H; Ruth, M; Adler, J; Silberg, DG; Sifrim, D,期刊:Gastroenterology, 页码:409-417 , 文章类型: Article,,卷期:2010年139-2]
- BACKGROUND & AIMS: Transient lower esophageal sphincter relaxations (TLESRs) are a major mechanism behind reflux. This study assessed the effects of lesogaberan (AZD3355), a novel gamma-aminobutyric acid type B receptor ...
- Oral Viscous Budesonide Is Effective in Children With Eosinophilic Esophagitis in a Randomized, Placebo-Controlled Trial
[作者:Dohil, R; Newbury, R; Fox, L; Bastian, J; Aceves, S,期刊:Gastroenterology, 页码:418-429 , 文章类型: Article,,卷期:2010年139-2]
- BACKGROUND & AIMS: Eosinophilic esophagitis (EoE) is caused by immunologic reactions to ingested/inhaled allergens. The diagnosis is considered if >= 15 eosinophils per high-powered field (eos/hpf) are detected in mucosa...
- Allele-Specific Expression of APC in Adenomatous Polyposis Families
[作者:Castellsague, E; Gonzalez, S; Guino, E; Stevens, KN; Borras, E; Raymond, VM; Lazaro, C; Blanco, I; Gruber, SB; Capella, G,期刊:Gastroenterology, 页码:439-447 , 文章类型: Article,,卷期:2010年139-2]
- BACKGROUND & AIMS: Germline mutations in the APC gene cause of most cases of familial adenomatous polyposis (FAP) and a lesser proportion of attenuated FAP (AFAP). Systematic analysis of APC at the RNA level could provid...
- Surgical Removal of Omental Fat Does Not Improve Insulin Sensitivity and Cardiovascular Risk Factors in Obese Adults
[作者:Fabbrini, E; Tamboli, RA; Magkos, F; Marks-Shulman, PA; Eckhauser, AW; Richards, WO; Klein, S; Abumrad, NN,期刊:Gastroenterology, 页码:448-455 , 文章类型: Article,,卷期:2010年139-2]
- BACKGROUND & AIMS: Visceral adipose tissue (VAT) is an important risk factor for the metabolic complications associated with obesity. Therefore, a reduction in VAT is considered an important target of obesity therapy. We...
- Hereditary Hemochromatosis: Pathogenesis, Diagnosis, and Treatment
[作者:Pietrangelo, A,期刊:Gastroenterology, 页码:393-408 , 文章类型: Article,,卷期:2010年139-2]
- In the late 1800s, hemochromatosis was considered an odd autoptic finding. More than a century later, it was finally recognized as a hereditary, multi-organ disorder associated with a polymorphism that is common among wh...
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