- Inflammatory Cortical Demyelination in Early Multiple Sclerosis
[作者:Lucchinetti, CF; Popescu, BFG; Bunyan, RF; Moll, NM; Roemer, SF; Lassmann, H; Bruck, W; Parisi, JE; Scheithauer, BW; Giannini, C; Weigand, SD; Mandrekar, J; Ransohoff, RM,期刊:New England Journal of Medicine, 页码:2188-2197 , 文章类型: Article,,卷期:2011年365-23]
- BACKGROUNDCortical disease has emerged as a critical aspect of the pathogenesis of multiple sclerosis, being associated with disease progression and cognitive impairment. Most studies of cortical lesions have focused on ...
- A Request for Abortion
[作者:Templeton, A; Grimes, DA,期刊:New England Journal of Medicine, 页码:2198-2204 , 文章类型: Article,,卷期:2011年365-23]
- A 22-year-old student presents to her primary care physician with an unintended pregnancy at 9 weeks of gestation and requests an abortion. She is aware of both medical (drug-induced) and surgical methods of terminating ...
- Three Months of Rifapentine and Isoniazid for Latent Tuberculosis Infection
[作者:Sterling, TR; Villarino, ME; Borisov, AS; Shang, N; Gordin, F; Bliven-Sizemore, E; Hackman, J; Hamilton, CD; Menzies, D; Kerrigan, A; Weis, SE; Weiner, M; Wing, D; Conde, MB; Bozeman, L; Horsburgh, CR; Chaisson, RE,期刊:New England Journal of Medicine, 页码:2155-2166 , 文章类型: Article,,卷期:2011年365-23]
- BACKGROUNDTreatment of latent Mycobacterium tuberculosis infection is an essential component of tuberculosis control and elimination. The current standard regimen of isoniazid for 9 months is efficacious but is limited b...
- Apixaban versus Enoxaparin for Thromboprophylaxis in Medically Ill Patients
[作者:Goldhaber, SZ; Leizorovicz, A; Kakkar, AK; Haas, SK; Merli, G; Knabb, RM; Weitz, JI,期刊:New England Journal of Medicine, 页码:2167-2177 , 文章类型: Article,,卷期:2011年365-23]
- BACKGROUNDThe efficacy and safety of prolonging prophylaxis for venous thromboembolism in medically ill patients beyond hospital discharge remain uncertain. We hypothesized that extended prophylaxis with apixaban would b...
- Norovirus Vaccine against Experimental Human Norwalk Virus Illness
[作者:Atmar, RL; Bernstein, DI; Harro, CD; Al-Ibrahim, MS; Chen, WH; Ferreira, J; Estes, MK; Graham, DY; Opekun, AR; Richardson, C; Mendelman, PM,期刊:New England Journal of Medicine, 页码:2178-2187 , 文章类型: Article,,卷期:2011年365-23]
- BACKGROUNDNoroviruses cause epidemic and sporadic acute gastroenteritis. No vaccine is available to prevent norovirus illness or infection.METHODSWe conducted a randomized, double-blind, placebo-controlled, multicenter t...
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