- Placebo-Controlled Trial of Cytisine for Smoking Cessation
[作者：West, R; Zatonski, W; Cedzynska, M; Lewandowska, D; Pazik, J; Aveyard, P; Stapleton, J,期刊：New England Journal of Medicine, 页码：1193-1200 , 文章类型： Article，,卷期：2011年365-13]
- BACKGROUND Cytisine, a partial agonist that binds with high affinity to the alpha(4)beta(2) nicotinic acetylcholine receptor, is a low-cost treatment that may be effective in aiding smoking cessation. This study assessed...
- Changes in Forced Expiratory Volume in 1 Second over Time in COPD
[作者：Vestbo, J; Edwards, LD; Scanlon, PD; Yates, JC; Agusti, A; Bakke, P; Calverley, PMA; Celli, B; Coxson, HO; Crim, C; Lomas, DA; MacNee, W; Miller, BE; Silverman, EK; Tal-Singer, R; Wouters, E; Rennard, SI,期刊：New England Journal of Medicine, 页码：1184-1192 , 文章类型： Article，,卷期：2011年365-13]
- BACKGROUND A key feature of chronic obstructive pulmonary disease (COPD) is an accelerated rate of decline in forced expiratory volume in 1 second (FEV(1)), but data on the variability and determinants of this change in ...
- Genomewide Association between GLCCI1 and Response to Glucocorticoid Therapy in Asthma
[作者：Tantisira, KG; Lasky-Su, J; Harada, M; Murphy, A; Litonjua, AA; Himes, BE; Lange, C; Lazarus, R; Sylvia, J; Klanderman, B; Duan, QL; Qiu, WL; Hirota, T; Martinez, FD; Mauger, D; Sorkness, C; Szefler, S; Lazarus, SC; Lemanske, RF; Peters, SP; Lima, JJ; Nakamura, Y; Tamari, M; Weiss, ST,期刊：New England Journal of Medicine, 页码：1173-1183 , 文章类型： Article，,卷期：2011年365-13]
- BACKGROUND The response to treatment for asthma is characterized by wide interindividual variability, with a significant number of patients who have no response. We hypothesized that a genomewide association study would ...
- End-of-Life Transitions among Nursing Home Residents with Cognitive Issues
[作者：Gozalo, P; Teno, JM; Mitchell, SL; Skinner, J; Bynum, J; Tyler, D; Mor, V,期刊：New England Journal of Medicine, 页码：1212-1221 , 文章类型： Article，,卷期：2011年365-13]
- BACKGROUND Health care transitions in the last months of life can be burdensome and potentially of limited clinical benefit for patients with advanced cognitive and functional impairment. METHODS To examine health care t...
- Treatment of Neonatal Sepsis with Intravenous Immune Globulin
[作者：Brocklehurst, P; Farrell, B; King, A; Juszczak, E; Darlow, B; Haque, K; Salt, A; Stenson, B; Tarnow-Mordi, W,期刊：New England Journal of Medicine, 页码：1201-1211 , 文章类型： Article，,卷期：2011年365-13]
- BACKGROUND Neonatal sepsis is a major cause of death and complications despite antibiotic treatment. Effective adjunctive treatments are needed. Newborn infants are relatively deficient in endogenous immunoglobulin. Meta...
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