- A Mammalian Siderophore Synthesized by an Enzyme with a Bacterial Homolog Involved in Enterobactin Production
[作者:Devireddy, LR; Hart, DO; Goetz, DH; Green, MR,期刊:Cell, 页码:1006-1017 , 文章类型: Article,,卷期:2010年141-6]
- Intracellular iron homeostasis is critical for survival and proliferation. Lipocalin 24p3 is an iron-trafficking protein that binds iron through association with a bacterial siderophore, such as enterobactin, or a postul...
- Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels
[作者:Clarke, OB; Caputo, AT; Hill, AP; Vandenberg, JI; Smith, BJ; Gulbis, JM,期刊:Cell, 页码:1018-1029 , 文章类型: Article,,卷期:2010年141-6]
- Potassium channels embedded in cell membranes employ gates to regulate K+ current. While a specific constriction in the permeation pathway has historically been implicated in gating, recent reports suggest that the signa...
- C. elegans Screen Identifies Autophagy Genes Specific to Multicellular Organisms
[作者:Tian, Y; Li, ZP; Hu, WQ; Ren, HY; Tian, E; Zhao, Y; Lu, Q; Huang, XX; Yang, PG; Li, X; Wang, XC; Kovacs, AL; Yu, L; Zhang, H,期刊:Cell, 页码:1042-1055 , 文章类型: Article,,卷期:2010年141-6]
- The molecular understanding of autophagy has originated almost exclusively from yeast genetic studies. Little is known about essential autophagy components specific to higher eukaryotes. Here we perform genetic screens i...
- Sequential Arrival and Graded Secretion of Sema3F by Olfactory Neuron Axons Specify Map Topography at the Bulb
[作者:Takeuchi, H; Inokuchi, K; Aoki, M; Suto, F; Tsuboi, A; Matsuda, I; Suzuki, M; Aiba, A; Serizawa, S; Yoshihara, Y; Fujisawa, H; Sakano, H,期刊:Cell, 页码:1056-1067 , 文章类型: Article,,卷期:2010年141-6]
- In the mouse olfactory system, the anatomical locations of olfactory sensory neurons (OSNs) roughly correlate with their axonal projection sites along the dorsal-ventral (D-V) axis of the olfactory bulb (OB). Here we rep...
- Trans-Synaptic Interaction of GluR delta 2 and Neurexin through Cbln1 Mediates Synapse Formation in the Cerebellum
[作者:Uemura, T; Lee, SJ; Yasumura, M; Takeuchi, T; Yoshida, T; Ra, M; Taguchi, R; Sakimura, K; Mishina, M,期刊:Cell, 页码:1068-1079 , 文章类型: Article,,卷期:2010年141-6]
- Elucidation of molecular mechanisms that regulate synapse formation is required for the understanding of neural wiring, higher brain functions, and mental disorders. Despite the wealth of in vitro information, fundamenta...
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