- A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression
[作者：Bernard, D; Prasanth, KV; Tripathi, V; Colasse, S; Nakamura, T; Xuan, ZY; Zhang, MQ; Sedel, F; Jourdren, L; Coulpier, F; Triller, A; Spector, DL; Bessis, A,期刊：EMBO journal, 页码：3082-3093 , 文章类型： Article，,卷期：2010年29-18]
- A growing number of long nuclear-retained non-coding RNAs (ncRNAs) have recently been described. However, few functions have been elucidated for these ncRNAs. Here, we have characterized the function of one such ncRNA, i...
- Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4
[作者：Polo, SE; Kaidi, A; Baskcomb, L; Galanty, Y; Jackson, SP,期刊：EMBO journal, 页码：3130-3139 , 文章类型： Article，,卷期：2010年29-18]
- The chromatin remodelling factor chromodomain helicase DNA-binding protein 4 (CHD4) is a catalytic subunit of the NuRD transcriptional repressor complex. Here, we reveal novel functions for CHD4 in the DNA-damage respons...
- Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication
[作者：Xu, DY; Muniandy, P; Leo, E; Yin, JH; Thangavel, S; Shen, X; Ii, M; Agama, K; Guo, R; Fox, D; Meetei, AR; Wilson, L; Nguyen, H; Weng, NP; Brill, SJ; Li, L; Vindigni, A; Pommier, Y; Seidman, M; Wang, WD,期刊：EMBO journal, 页码：3140-3155 , 文章类型： Article，,卷期：2010年29-18]
- BLM, the helicase defective in Bloom syndrome, is part of a multiprotein complex that protects genome stability. Here, we show that Rif1 is a novel component of the BLM complex and works with BLM to promote recovery of s...
- ATR and ATM differently regulate WRN to prevent DSBs at stalled replication forks and promote replication fork recovery
[作者：Ammazzalorso, F; Pirzio, LM; Bignami, M; Franchitto, A; Pichierri, P,期刊：EMBO journal, 页码：3156-3169 , 文章类型： Article，,卷期：2010年29-18]
- Accurate response to replication arrest is crucial to preserve genome stability and requires both the ATR and ATM functions. The Werner syndrome protein (WRN) is implicated in the recovery of stalled replication forks, a...
- alpha-Catulin CTN-1 is required for BK channel subcellular localization in C. elegans body-wall muscle cells
[作者：Chen, BJ; Liu, P; Wang, SJ; Ge, QA; Zhan, HY; Mohler, WA; Wang, ZW,期刊：EMBO journal, 页码：3184-3195 , 文章类型： Article，,卷期：2010年29-18]
- The BK channel, a voltage- and Ca2+-gated large-conductance potassium channel with many important functions, is often localized at specific subcellular domains. Although proper subcellular localization is likely a prereq...
- Metabolic regulation of Drosophila apoptosis through inhibitory phosphorylation of Dronc
[作者：Yang, CS; Thomenius, MJ; Gan, EC; Tang, WL; Freel, CD; Merritt, TJS; Nutt, LK; Kornbluth, S,期刊：EMBO journal, 页码：3196-3207 , 文章类型： Article，,卷期：2010年29-18]
- Apoptosis ensures tissue homeostasis in response to developmental cues or cellular damage. Recently reported genome-wide RNAi screens have suggested that several metabolic regulators can modulate caspase activation in Dr...
- Growth habit determination by the balance of histone methylation activities in Arabidopsis
[作者：Ko, JH; Mitina, I; Tamada, Y; Hyun, Y; Choi, Y; Amasino, RM; Noh, B; Noh, YS,期刊：EMBO journal, 页码：3208-3215 , 文章类型： Article，,卷期：2010年29-18]
- In Arabidopsis, the rapid-flowering summer-annual versus the vernalization-requiring winter-annual growth habit is determined by natural variation in FRIGIDA (FRI) and FLOWERING LOCUS C (FLC). However, the biochemical ba...
- Target practice: Zic2 hits the bullseye!
[作者：Wilson, SI,期刊：EMBO journal, 页码：3037-3038 , 文章类型： Editorial Material，,卷期：2010年29-18]
- A major challenge in biology is to unravel how the billions of neurons of the nervous system make appropriate functional connections. This is known to be a multistep developmental process that includes guiding, targeting...
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