- Heat shock factor 1 ameliorates proteotoxicity in cooperation with the transcription factor NFAT
[作者：Hayashida, N; Fujimoto, M; Tan, K; Prakasam, R; Shinkawa, T; Li, LP; Ichikawa, H; Takii, R; Nakai, A,期刊：EMBO journal, 页码：3459-3469 , 文章类型： Article，,卷期：2010年29-20]
- Heat shock transcription factor 1 (HSF1) is an important regulator of protein homeostasis (proteostasis) by controlling the expression of major heat shock proteins (Hsps) that facilitate protein folding. However, it is u...
- Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1
[作者：Kikuchi, K; Niikura, Y; Kitagawa, K; Kikuchi, A,期刊：EMBO journal, 页码：3470-3483 , 文章类型： Article，,卷期：2010年29-20]
- Wnt signalling is known to promote G1/S progression through the stimulation of gene expression, but whether this signalling regulates mitotic progression is not clear. Here, the function of dishevelled 2 (Dvl2), which tr...
- Differences in signalling by directly and indirectly binding ligands in bacterial chemotaxis
[作者：Neumann, S; Hansen, CH; Wingreen, NS; Sourjik, V,期刊：EMBO journal, 页码：3484-3495 , 文章类型： Article，,卷期：2010年29-20]
- In chemotaxis of Escherichia coil and other bacteria, extracellular stimuli are perceived by transmembrane receptors that bind their ligands either directly, or indirectly through periplasmic-binding proteins (BPs). As B...
- Autocatalytic differentiation of epigenetic modifications within the Arabidopsis genome
[作者：Inagaki, S; Miura-Kamio, A; Nakamura, Y; Lu, FL; Cui, X; Cao, XF; Kimura, H; Saze, H; Kakutani, T,期刊：EMBO journal, 页码：3496-3506 , 文章类型： Article，,卷期：2010年29-20]
- In diverse eukaryotes, constitutively silent sequences, such as transposons and repeats, are marked by methylation at histone H3 lysine 9 (H3K9me). Although selective H3K9me is critical for maintaining genome integrity, ...
- Plant virus-mediated induction of miR168 is associated with repression of ARGONAUTE1 accumulation
[作者：Varallyay, E; Valoczi, A; Agyi, A; Burgyan, J; Havelda, Z,期刊：EMBO journal, 页码：3507-3519 , 文章类型： Article，,卷期：2010年29-20]
- Virus infections induce the expression of ARGONAUTE1 (AGO1) mRNA and in parallel enhance the accumulation of miR168 (regulator of AGO1) mRNA). Here, we show that in virus-infected plants the enhanced expression of AGO1 m...
- CLASP1, astrin and Kif2b form a molecular switch that regulates kinetochore-microtubule dynamics to promote mitotic progression and fidelity
[作者：Manning, AL; Bakhoum, SF; Maffini, S; Correia-Melo, C; Maiato, H; Compton, DA,期刊：EMBO journal, 页码：3531-3543 , 文章类型： Article，,卷期：2010年29-20]
- Accurate chromosome segregation during mitosis requires precise coordination of various processes, such as chromosome alignment, maturation of proper kinetochore-microtubule (kMT) attachments, correction of erroneous att...
- The hsSsu72 phosphatase is a cohesin-binding protein that regulates the resolution of sister chromatid arm cohesion
[作者：Kim, HS; Baek, KH; Ha, GH; Lee, JC; Kim, YN; Lee, J; Park, HY; Lee, NR; Lee, H; Cho, Y; Lee, CW,期刊：EMBO journal, 页码：3544-3557 , 文章类型： Article，,卷期：2010年29-20]
- Cohesin is a multiprotein complex that establishes sister chromatid cohesion from S phase until mitosis or meiosis. In vertebrates, sister chromatid cohesion is dissolved in a stepwise manner: most cohesins are removed f...
- Cooperative functions of Chk1 and Chk2 reduce tumour susceptibility in vivo
[作者：Niida, H; Murata, K; Shimada, M; Ogawa, K; Ohta, K; Suzuki, K; Fujigaki, H; Khaw, AK; Banerjee, B; Hande, MP; Miyamoto, T; Miyoshi, I; Shirai, T; Motoyama, N; Delhase, M; Appella, E; Nakanishi, M,期刊：EMBO journal, 页码：3558-3570 , 文章类型： Article，,卷期：2010年29-20]
- Although the linkage of Chk1 and Chk2 to important cancer signalling suggests that these kinases have functions as tumour suppressors, neither Chk1(+/-) nor Chk2(-/-) mice show a predisposition to cancer under unperturbe...
- Inhibition of mitochondrial fusion by alpha-synuclein is rescued by PINK1, Parkin and DJ-1
[作者：Kamp, F; Exner, N; Lutz, AK; Wender, N; Hegermann, J; Brunner, B; Nuscher, B; Bartels, T; Giese, A; Beyer, K; Eimer, S; Winklhofer, KF; Haass, C,期刊：EMBO journal, 页码：3571-3589 , 文章类型： Article，,卷期：2010年29-20]
- Aggregation of alpha-synuclein (alpha S) is involved in the pathogenesis of Parkinson's disease (PD) and a variety of related neurodegenerative disorders. The physiological function of alpha S is largely unknown. We demo...
- Insight into the molecular mechanism of the multitasking kinesin-8 motor
[作者：Peters, C; Brejc, K; Belmont, L; Bodey, AJ; Lee, Y; Yu, M; Guo, J; Sakowicz, R; Hartman, J; Moores, CA,期刊：EMBO journal, 页码：3437-3447 , 文章类型： Article，,卷期：2010年29-20]
- Members of the kinesin-8 motor class have the remarkable ability to both walk towards microtubule plus-ends and depolymerise these ends on arrival, thereby regulating microtubule length. To analyse how kinesin-8 multitas...
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