- Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions
[作者：Leone, P; Comoletti, D; Ferracci, G; Conrod, S; Garcia, SU; Taylor, P; Bourne, Y; Marchot, P,期刊：EMBO journal, 页码：2461-2471 , 文章类型： Article，,卷期：2010年29-14]
- The extracellular domains of neuroligins and neurexins interact through Ca2+ to form flexible trans-synaptic associations characterized by selectivity for neuroligin or neurexin subtypes. This heterophilic interaction, e...
- Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function (vol 29, pg 1489, 2010)
[作者：Manford, A; Xia, TA; Saxena, AK; Stefan, C; Hu, FH; Emr, SD; Mao, YX,期刊：EMBO journal, 页码：2472-2472 , 文章类型： Correction，,卷期：2010年29-14]
- Stalling in mitosis and releasing the apoptotic brake
[作者：Kurokawa, M; Kornbluth, S,期刊：EMBO journal, 页码：2255-2257 , 文章类型： Editorial Material，,卷期：2010年29-14]
- Microtubule poisons induce mitotic arrest that leads to apoptotic cell death if not resolved in a timely manner, but the mechanisms that directly link this cell cycle arrest to apoptosis have been elusive. In this issue ...
- Twins take the job
[作者：Gas, ME; Seraphin, B,期刊：EMBO journal, 页码：2260-2261 , 文章类型： Editorial Material，,卷期：2010年29-14]
- The exosome, one of the main cellular ribonucleases in eukaryotes, is a multi-subunit complex of deep evolutionary origin. This complex has been extensively characterized in Saccharomyces cerevisae. Given the good conser...
- A classical NLS and the SUN domain contribute to the targeting of SUN2 to the inner nuclear membrane
[作者：Turgay, Y; Ungricht, R; Rothballer, A; Kiss, A; Csucs, G; Horvath, P; Kutay, U,期刊：EMBO journal, 页码：2262-2275 , 文章类型： Article，,卷期：2010年29-14]
- Integral membrane proteins of the inner nuclear membrane (INM) are inserted into the endoplasmic reticulum membrane during their biogenesis and are then targeted to their final destination. We have used human SUN2 to del...
- Regulation of dynamic polarity switching in bacteria by a Ras-like G-protein and its cognate GAP
[作者：Leonardy, S; Miertzschke, M; Bulyha, I; Sperling, E; Wittinghofer, A; Sogaard-Andersen, L,期刊：EMBO journal, 页码：2276-2289 , 文章类型： Article，,卷期：2010年29-14]
- The rod-shaped cells of the bacterium Myxococcus xanthus move uni-directionally and occasionally undergo reversals during which the leading/lagging polarity axis is inverted. Cellular reversals depend on pole-to-pole rel...
- Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse
[作者：Lasserre, R; Charrin, S; Cuche, C; Danckaert, A; Thoulouze, MI; de Chaumont, F; Duong, T; Perrault, N; Varin-Blank, N; Olivo-Marin, JC; Etienne-Manneville, S; Arpin, M; Di Bartolo, V; Alcover, A,期刊：EMBO journal, 页码：2301-2314 , 文章类型： Article，,卷期：2010年29-14]
- T-cell receptor (TCR) signalling is triggered and tuned at immunological synapses by the generation of signalling complexes that associate into dynamic microclusters. Microcluster movement is necessary to tune TCR signal...
- Cooperative interactions at the SLP-76 complex are critical for actin polymerization
[作者：Barda-Saad, M; Shirasu, N; Pauker, MH; Hassan, N; Perl, O; Balbo, A; Yamaguchi, H; Houtman, JCD; Appella, E; Schuck, P; Samelson, LE,期刊：EMBO journal, 页码：2315-2328 , 文章类型： Article，,卷期：2010年29-14]
- T-cell antigen receptor (TCR) engagement induces formation of multi-protein signalling complexes essential for regulating T-cell functions. Generation of a complex of SLP-76, Nck and VAV1 is crucial for regulation of the...
- TCR-mediated ThPOK induction promotes development of mature (CD24-) gamma delta thymocytes
[作者：Park, K; He, X; Lee, HO; Hua, XA; Li, Y; Wiest, D; Kappes, DJ,期刊：EMBO journal, 页码：2329-2341 , 文章类型： Article，,卷期：2010年29-14]
- T lymphocytes develop into two major lineages characterized by expression of the alpha beta and gamma delta T cell receptor (TCR) heterodimers. Within each major lineage, further specialization occurs, resulting in disti...
- The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L
[作者：Tomecki, R; Kristiansen, MS; Lykke-Andersen, S; Chlebowski, A; Larsen, KM; Szczesny, RJ; Drazkowska, K; Pastula, A; Andersen, JS; Stepien, PP; Dziembowski, A; Jensen, TH,期刊：EMBO journal, 页码：2342-2357 , 文章类型： Article，,卷期：2010年29-14]
- The eukaryotic RNA exosome is a ribonucleolytic complex involved in RNA processing and turnover. It consists of a nine-subunit catalytically inert core that serves a structural function and participates in substrate reco...
- Dis3-like 1: a novel exoribonuclease associated with the human exosome
[作者：Staals, RHJ; Bronkhorst, AW; Schilders, G; Slomovic, S; Schuster, G; Heck, AJR; Raijmakers, R; Pruijn, GJM,期刊：EMBO journal, 页码：2358-2367 , 文章类型： Article，,卷期：2010年29-14]
- The exosome is an exoribonuclease complex involved in the degradation and maturation of a wide variety of RNAs. The nine-subunit core of the eukaryotic exosome is catalytically inactive and may have an architectural func...
- The C-terminal alpha-alpha superhelix of Pat is required for mRNA decapping in metazoa
[作者：Braun, JE; Tritschler, F; Haas, G; Igreja, C; Truffault, V; Weichenrieder, O; Izaurralde, E,期刊：EMBO journal, 页码：2368-2380 , 文章类型： Article，,卷期：2010年29-14]
- Pat proteins regulate the transition of mRNAs from a state that is translationally active to one that is repressed, committing targeted mRNAs to degradation. Pat proteins contain a conserved N-terminal sequence, a prolin...
- The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates
[作者：Orpinell, M; Fournier, M; Riss, A; Nagy, Z; Krebs, AR; Frontini, M; Tora, L,期刊：EMBO journal, 页码：2381-2394 , 文章类型： Article，,卷期：2010年29-14]
- All DNA-related processes rely on the degree of chromatin compaction. The highest level of chromatin condensation accompanies transition to mitosis, central for cell cycle progression. Covalent modifications of histones,...
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