- HSV-1-derived helper-independent defective vectors, replicating vectors and amplicon vectors, for the treatment of brain diseases
[作者:Marconi, P; Manservigi, R; Epstein, AL,期刊:Current Opinion in Drug Discovery & Development, 页码:169-183 , 文章类型: Review,,卷期:2010年13-2]
- HSV-1 is a neurotropic virus that displays several important adaptations to the nervous system of the host organism, each of which can be rationally exploited in the design of gene therapy vectors for neurological applic...
- Contemporary immunotherapy of solid tumors: From tumor-associated antigens to combination treatments
[作者:Spagnoli, GC; Ebrahimi, M; Iezzi, G; Mengus, C; Zajac, P,期刊:Current Opinion in Drug Discovery & Development, 页码:184-192 , 文章类型: Review,,卷期:2010年13-2]
- The possibility of using the immune system of patients to control tumor outgrowth in a therapeutic setting has always been highly appealing to both clinicians and researchers. However, although cancer cells express tumor...
- Novel therapeutics for Alzheimer's disease: An update
[作者:Bonda, DJ; Lee, HP; Lee, HG; Friedlich, AL; Perry, G; Zhu, XW; Smith, MA,期刊:Current Opinion in Drug Discovery & Development, 页码:235-246 , 文章类型: Review,,卷期:2010年13-2]
- As the most prevalent form of dementia worldwide, Alzheimer's disease (AD) continues to be a burden for patients and their families. In addition, with the global population of aged individuals increasing exponentially, A...
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