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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共15条记录   Effects of substitutions in the CXXC active-site motif of the extracytoplasmic thioredoxin ResA [作者：Lewin, A; Crow, A; Hodson, CTC; Hederstedt, L; Le Brun, NE,期刊：Biochemical Journal, 页码：81-91 , 文章类型： Article，,卷期：2008年414-1] The thiol-disulfide oxidoreductase ResA from Bacillus subtilis fulfils a reductive role in cytochrome c maturation. The pK(a) values for the CEPC (one-letter code) active-site cysteine residues of Ill are unusual for thi... Gisplatin-mediated impairment of mitochondrial DNA metabolism inversely correlates with glutathione levels [作者：Garrido, N; Perez-Martos, A; Faro, M; Lou-Bonafonte, JM; Fernandez-Silva, P; Lopez-Perez, MJ; Montoya, J; Enriquez, JA,期刊：Biochemical Journal, 页码：93-102 , 文章类型： Article，,卷期：2008年414-1] Cisplatin accumulates in mitochondria, which are a major target for this drug in cancer cells. Thus alterations in mitochondrial function have been implicated in cancer cell resistance to chemotherapeutic agents. Moreove... Targeting human glutathione transferase A3-3 attenuates progesterone production in human steroidogenic cells [作者：Raffalli-Mathieu, F; Orre, C; Stridsberg, M; Edalat, MH; Mannervik, B,期刊：Biochemical Journal, 页码：103-109 , 文章类型： Article，,卷期：2008年414-1] hGSTA3-3 (human Alpha-class glutathione transferase 3-3) efficiently catalyses steroid Delta(5)-Delta(4) double-bond isomerization in vitro, using glutathione as a cofactor. This chemical transformation is an obligatory ... Heat shock and ethanol stress provoke distinctly different responses in 3 '-processing and nuclear export of HSP mRNA in Saccharomyces cerevisiae [作者：Izawa, S; Kita, T; Ikeda, K; Inoue, Y,期刊：Biochemical Journal, 页码：111-119 , 文章类型： Article，,卷期：2008年414-1] Under conditions of hear shock at 42 degrees C, mRNAs of HSP (heat shock protein) genes are exported out of the nucleus, whereas bulk poly(A)(+) (polyadenylated) mRNA shows a nuclear accumulation in Saccharomyces cerevis... Cloning and characterization of dominant negative splice variants of the human histamine H-4 receptor [作者：van Rijn, RM; van Marle, A; Chazot, PL; Langemeijer, E; Qin, Y; Shenton, FC; Lim, HD; Zuiderveld, OP; Sansuk, K; Dy, M; Smit, MJ; Tensen, CP; Bakker, RA; Leurs, R,期刊：Biochemical Journal, 页码：121-131 , 文章类型： Article，,卷期：2008年414-1] The H4R (histamine H-4 receptor) is the latest identified member of the histamine receptor subfamily of GPCRs (G-protein-coupled receptors) with potential functional implications in inflammatory diseases and cancer. The ... Topology mapping of the vacuolar Vcx1p Ca2+/(H+) exchanger from Saccharomyces cerevisiae [作者：Segarra, VA; Thomas, L,期刊：Biochemical Journal, 页码：133-141 , 文章类型： Article，,卷期：2008年414-1] Saccharomyces cerevisiae uses vacuolar storage to dynamically control the cytoplasmic calcium concentration. Vex1p, a Ca2+/H+ antiporter and a member of file CAX (Ca2+/anion exchanger) family of exchangers, is one of the... Probing structure-activity relationships in bactericidal peptide beta pep-25 [作者：Dings, RPM; Haseman, JR; Mayo, KH,期刊：Biochemical Journal, 页码：143-150 , 文章类型： Article，,卷期：2008年414-1] Cationic peptides, known to disrupt bacterial membranes, are being developed as promising agents for therapeutic intervention against infections disease. In the present study, we investigate structure-activity relationsh... Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta-lactamase from Aeromonas hydrophila [作者：Bebrone, C; Anne, C; Kerff, F; Garau, G; De Vriendt, K; Lantin, R; Devreese, B; Van Beeumen, J; Dideberg, O; Frere, JM; Galleni, M,期刊：Biochemical Journal, 页码：151-159 , 文章类型： Article，,卷期：2008年414-1] The subclass B2 CphA (Carbapenemase hydrolysing Aeromonas) beta-lactamase from Aeromonas hydrophila is a Zn2+-containing enzyme that specifically hydrolyses carbapenems. In an effort to evaluate residues potentially invo... Glucokinase and molecular aspects of liver glycogen metabolism [作者：Agius, L,期刊：Biochemical Journal, 页码：1-18 , 文章类型： Review，,卷期：2008年414-1] Conversion of glucose into glycogen is a major pathway that contributes to the removal of glucose from the portal vein by the liver in the postprandial state. It is regulated in part by the increase in blood-glucose conc... Regulation of gene expression by hypoxia [作者：Kenneth, NS; Rocha, S,期刊：Biochemical Journal, 页码：19-29 , 文章类型： Review，,卷期：2008年414-1] Hypoxia induces profound changes in the cellular gene expression profile. The discovery of a major transcription factor family activated by hypoxia, HIF (hypoxia-inducible factor), and the factors that contribute to HIF ... Sphingomyelin synthases regulate production of diacylglycerol at the Golgi [作者：Villani, M; Subathra, M; Im, YB; Choi, Y; Signorelli, P; Del Poeta, M; Luberto, C,期刊：Biochemical Journal, 页码：31-41 , 文章类型： Article，,卷期：2008年414-1] SMS [SM (sphingomyelin) synthase] is a class of enzymes that produces SM by transferring a phosphocholine moiety on to ceramide. PC (phosphatidylcholine) is believed to be the phosphocholine donor of the reaction with co... Molecular control of the glucan synthase-like protein NaGSL1 and callose synthesis during growth of Nicotiana alata pollen tubes [作者：Brownfield, L; Wilson, S; Newbigin, E; Bacic, A; Read, S,期刊：Biochemical Journal, 页码：43-52 , 文章类型： Article，,卷期：2008年414-1] The protein NaGSL1 (Nicotiona alata glucan synthase-like 1) is implicated in the synthesis of callose, the 1,3-beta-glucan that is the major polysaccharide in the walls of N. alata (flowering tobacco) pollen tubes. Here ... Plant plasma membrane water channels conduct the signalling molecule H2O2 [作者：Dynowski, M; Schaaf, G; Loque, D; Moran, O; Ludewig, U,期刊：Biochemical Journal, 页码：53-61 , 文章类型： Article，,卷期：2008年414-1] H2O2 is a relatively long-lived reactive oxygen species that signals between cells and organisms. H2O2 signalling in plants is essential for response to stress, defence against pathogeris and the regulation of programmed... MAPI structural organization in Drosophila: in vivo analysis of FUTSCH reveals heavy- and light-chain subunits generated by proteolytic processing at a conserved cleavage site [作者：Zou, B; Yan, H; Kawasaki, F; Ordway, RW,期刊：Biochemical Journal, 页码：63-71 , 文章类型： Article，,卷期：2008年414-1] The MAP1 (microtubule-associated protein 1) family is a class of microtubule-binding proteins represented by mammalian MAP1A, MAP1B and the recently identified MAP1S. MAP1A and MAP1B are expressed in the nervous system a... Variants of the tetrahaem cytochrome c quinol dehydrogenase NrfH characterize the menaquinol-binding site, the haem c-binding motifs and the transmembrane segment [作者：Kern, M; Einsle, O; Simon, J,期刊：Biochemical Journal, 页码：73-79 , 文章类型： Article，,卷期：2008年414-1] Members of the NapC/NrfH family are multihaem c-type cytochromes that exchange electrons with oxidoreductases situated at the outside of the cytoplasmic membrane or in the periplasmic space of many proteobacteria. They f...