- Implications of the Dominant Role of Transporters in Drug Uptake by Cells
[作者:Dobson, PD; Lanthaler, K; Oliver, SG; Kell, DB,期刊:Current Topics in Medicinal Chemistry, 页码:163-181 , 文章类型: Review,,卷期:2009年9-2]
- Drug entry into cells was previously believed to be via diffusion through the lipid bilayer of the cell membrane, with the contribution to uptake by transporter proteins being of only marginal importance. Now, however, d...
- P-gp Transporter and its Role in Neurodegenerative Diseases
[作者:Rapposelli, S; Digiacomo, M; Balsamo, A,期刊:Current Topics in Medicinal Chemistry, 页码:209-217 , 文章类型: Review,,卷期:2009年9-2]
- This paper describes an overview of recent insights concerning some socially relevant neurodegenerative diseases such as Alzheimer's (AD), Parkinson's (PD), Huntington's (HD) and Creutzfeldt-Jakob's (CJD) diseases, amyot...
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