- Hepatic steatosis inhibits autophagic proteolysis via impairment of autophagosomal acidification and cathepsin expression
[作者:Inami, Y; Yamashina, S; Izumi, K; Ueno, T; Tanida, I; Ikejima, K; Watanabe, S,期刊:Biochemical and Biophysical Research Communications, 页码:618-625 , 文章类型: Article,,卷期:2011年412-4]
- Autophagy, one of protein degradation system, contributes to maintain cellular homeostasis and cell defense. Recently, some evidences indicated that autophagy and lipid metabolism are interrelated. Here, we demonstrate t...
- A novel splicing variant of CADM2 as a protective transcript of psoriasis
[作者:Hiruma, A; Ikeda, S; Terui, T; Ozawa, M; Hashimoto, T; Yasumoto, S; Nakayama, J; Kubota, Y; Iijima, M; Sueki, H; Matsumoto, Y; Kato, M; Akasaka, E; Ikoma, N; Mabuchi, T; Tamiya, S; Matsuyama, T; Ozawa, A; Inoko, H; Oka, A,期刊:Biochemical and Biophysical Research Communications, 页码:626-632 , 文章类型: Article,,卷期:2011年412-4]
- CADM2, a candidate gene for psoriasis, was identified by a genome-wide association study using microsatellites in the Japanese population (561 cases and 561 controls). Moreover, haplotype analysis included an additional ...
- Kruppel-like factor-10 is directly regulated by carbohydrate response element-binding protein in rat primary hepatocytes
[作者:Iizuka, K; Takeda, J; Horikawa, Y,期刊:Biochemical and Biophysical Research Communications, 页码:638-643 , 文章类型: Article,,卷期:2011年412-4]
- Kruppel-like factor (KLF)-10, is a circadian transcriptional regulator, which links the molecular clock to energy metabolism in the liver. Recently, it was reported that Klf-10 expression is induced by glucose stimulatio...
- REDD1 (regulated in development and DNA damage response 1) expression in skeletal muscle as a surrogate biomarker of the efficiency of glucocorticoid receptor blockade
[作者:Kumari, R; Willing, LB; Jefferson, LS; Simpson, IA; Kimball, SR,期刊:Biochemical and Biophysical Research Communications, 页码:644-647 , 文章类型: Article,,卷期:2011年412-4]
- Glucocorticoids are potent regulators of cell metabolism, and in part act through a receptor-based mechanism to alter the transcription of target genes. A plethora of studies have utilized the glucocorticoid receptor ant...
- The transcription factor Grainyhead like 3 (GRHL3) affects endothelial cell apoptosis and migration in a NO-dependent manner
[作者:Lukosz, M; Mlynek, A; Czypiorski, P; Altschmied, J; Haendeler, J,期刊:Biochemical and Biophysical Research Communications, 页码:648-653 , 文章类型: Article,,卷期:2011年412-4]
- Migratory capacity and resistance to apoptosis are crucial for proper endothelial function. In a screen for anti-apoptotic genes in a breast cancer cell line, we identified Grainyhead like 3 (GRHL3). Therefore, the aim o...
- DAX1 suppresses FXR transactivity as a novel co-repressor
[作者:Li, J; Lu, Y; Liu, RY; Xiong, XL; Zhang, ZJ; Zhang, XF; Ning, G; Li, XY,期刊:Biochemical and Biophysical Research Communications, 页码:660-666 , 文章类型: Article,,卷期:2011年412-4]
- Bile acid receptor FXR (farnesoid X receptor) is a key regulator of hepatic bile acid, glucose and lipid homeostasis through regulation of numerous genes involved in the process of bile acid, triglyceride and glucose met...
- Characterization of novel antimicrobial peptides from the skin of the endangered frog Odorrana ishikawae by shotgun cDNA cloning
[作者:Iwakoshi-Ukena, E; Soga, M; Okada, G; Fujii, T; Sumida, M; Ukena, K,期刊:Biochemical and Biophysical Research Communications, 页码:673-677 , 文章类型: Article,,卷期:2011年412-4]
- We recently reported the primary structures, antimicrobial activities and cDNA precursors of nine novel antimicrobial peptides from the skin of the endangered anuran species, Odorrana ishikawae. Their cDNA clones reveale...
- Matrix vesicles isolated from mineralization-competent Saos-2 cells are selectively enriched with annexins and S100 proteins
[作者:Cmoch, A; Strzelecka-Kiliszek, A; Palczewska, M; Groves, P; Pikula, S,期刊:Biochemical and Biophysical Research Communications, 页码:683-687 , 文章类型: Article,,卷期:2011年412-4]
- Matrix vesicles (MVs) are cell-derived membranous entities crucial for mineral formation in the extracellular matrix. One of the dominant groups of constitutive proteins present in MVs, recognised as regulators of minera...
- Folic acid supplementation dysregulates gene expression in lymphoblastoid cells - Implications in nutrition
[作者:Junaid, MA; Kuizon, S; Cardona, J; Azher, T; Murakami, N; Pullarkat, RK; Brown, WT,期刊:Biochemical and Biophysical Research Communications, 页码:688-692 , 文章类型: Article,,卷期:2011年412-4]
- For over a decade, folic acid (FA) supplementation has been widely prescribed to pregnant women to prevent neural tube closure defects in newborns. Although neural tube closure occurs within the first trimester, high dos...
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