- Introduction of a negative charge at Arg82 in thaumatin abolished responses to human T1R2-T1R3 sweet receptors
[作者:Ohta, K; Masuda, T; Tani, F; Kitabatake, N,期刊:Biochemical and Biophysical Research Communications, 页码:41-45 , 文章类型: Article,,卷期:2011年413-1]
- Thaumatin, an intensely sweet-tasting protein, elicits a sweet-taste sensation at a level as low as 50 nM. Although previous sensory analyses have suggested that Lys67 and Arg82 are important to the sweetness of thaumati...
- An information integration model of the primary visual cortex under grating stimulations
[作者:Wang, ZZ; Shi, L; Wan, H; Niu, XK,期刊:Biochemical and Biophysical Research Communications, 页码:5-9 , 文章类型: Article,,卷期:2011年413-1]
- During the course of information processing, a visual system extracts characteristic information of the visual image and integrates the spatial and temporal visual information simultaneously. In this study, we investigat...
- Fluorescent metal nanoshell and CK19 detection on single cell image
[作者:Zhang, J; Fu, Y; Li, G; Lakowicz, JR; Zhao, RY,期刊:Biochemical and Biophysical Research Communications, 页码:53-57 , 文章类型: Article,,卷期:2011年413-1]
- In this article, we report the synthesis strategy and optical properties of a novel type of fluorescence metal nanoshell when it was used as imaging agent for fluorescence cell imaging. The metal nanoshells were made wit...
- Crystal structure of the Cys2His2-type zinc finger domain of human DPF2
[作者:Zhang, W; Xu, C; Bian, CB; Tempel, W; Crombet, L; MacKenzie, F; Min, JR; Liu, ZL; Qi, C,期刊:Biochemical and Biophysical Research Communications, 页码:58-61 , 文章类型: Article,,卷期:2011年413-1]
- DPF2 is an evolutionary highly conserved member of the d4-protein family characterized by an N-terminal 2/3 domain, a C2H2-type zinc finger (ZF), and a C-terminal tandem PHD zinc finger. DPF2 is identified as a transcrip...
- Sensitivity of malignant rhabdoid tumor cell lines to PD 0332991 is inversely correlated with p16 expression
[作者:Katsumi, Y; Iehara, T; Miyachi, M; Yagyu, S; Tsubai-Shimizu, S; Kikuchi, K; Tamura, S; Kuwahara, Y; Tsuchiya, K; Kuroda, H; Sugimoto, T; Houghton, PJ; Hosoi, H,期刊:Biochemical and Biophysical Research Communications, 页码:62-68 , 文章类型: Article,,卷期:2011年413-1]
- Malignant rhabdoid tumor (MRT) is a rare and highly aggressive neoplasm of young children. MRT is characterized by inactivation of integrase interactor 1 (INI1). Cyclin-dependent kinase 4 (CDK4), which acts downstream of...
- Human kidney anion exchanger 1 interacts with kinesin family member 3B (KIF3B)
[作者:Duangtum, N; Junking, M; Sawasdee, N; Cheunsuchon, B; Limjindaporn, T; Yenchitsomanus, PT,期刊:Biochemical and Biophysical Research Communications, 页码:69-74 , 文章类型: Article,,卷期:2011年413-1]
- Impaired trafficking of human kidney anion exchanger I (kAE1) to the basolateral membrane of alpha-intercalated cells of the kidney collecting duct leads to the defect of the Cl(-)/HCO(3)(-) exchange and the failure of p...
- Bacterial persisters tolerate antibiotics by not producing hydroxyl radicals
[作者:Kim, JS; Heo, P; Yang, TJ; Lee, KS; Jin, YS; Kim, SK; Shin, D; Kweon, DH,期刊:Biochemical and Biophysical Research Communications, 页码:105-110 , 文章类型: Article,,卷期:2011年413-1]
- In a phenomenon called persistence, small numbers of bacterial cells survive even after exposure to antibiotics. Recently, bactericidal antibiotics have been demonstrated to kill bacteria by increasing the levels of hydr...
- Src family protein tyrosine kinases modulate L-type calcium current in human atrial myocytes
[作者:Bogdelis, A; Treinys, R; Stankevicius, E; Jurevicius, J; Skeberdis, VA,期刊:Biochemical and Biophysical Research Communications, 页码:116-121 , 文章类型: Article,,卷期:2011年413-1]
- In the heart, L-type voltage dependent calcium channels (L-VDCC) provide Ca(2+) for the activation of contractile apparatus. The best described pathway for L-type Ca(2+) current (I(Ca,L)) modulation is the phosphorylatio...
- Targeting CD9 produces stimulus-independent antiangiogenic effects predominantly in activated endothelial cells during angiogenesis: A novel antiangiogenic therapy
[作者:Kamisasanuki, T; Tokushige, S; Terasaki, H; Khai, NC; Wang, YQ; Sakamoto, T; Kosai, K,期刊:Biochemical and Biophysical Research Communications, 页码:128-135 , 文章类型: Article,,卷期:2011年413-1]
- The precise roles of tetraspanin CD9 are unclear. Here we show that CD9 plays a stimulus-independent role in angiogenesis and that inhibiting CD9 expression or function is a potential antiangiogenic therapy. Knocking dow...
- Co-existence of major and minor viral populations from two different origins in patients secondarily infected with dengue virus serotype 2 in Bangkok
[作者:Puiprom, O; Yamashita, A; Sasayama, M; Limkittikul, K; Boonha, K; Jittmitraphap, A; Leaungwutiwong, P; Kurosu, T; Ramasoota, P; Ikuta, K,期刊:Biochemical and Biophysical Research Communications, 页码:136-142 , 文章类型: Article,,卷期:2011年413-1]
- Generally, RNA viruses exhibit significant genetic diversity that sometimes effect viral fitness in infected hosts and probably also pathogenesis. Dengue viruses (DENVs) consist of four antigenically distinct sertypes. A...
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