- Phospholipase D2 activation by p38 MAP kinase is involved in neurite outgrowth
[作者:Watanabe, H; Hongu, T; Yamazaki, M; Kanaho, Y,期刊:Biochemical and Biophysical Research Communications, 页码:288-293 , 文章类型: Article,,卷期:2011年413-2]
- p38 mitogen-activated protein (MAP) kinase plays an important role in neurite outgrowth. However, the underlying molecular mechanism(s) remains unclear. Here, we demonstrate that phospholipase 02 (PLD2) mediates p38 sign...
- Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1 alpha pathway
[作者:Liu, LZ; Jing, Y; Jiang, LL; Jiang, XE; Jiang, Y; Rojanasakul, Y; Jiang, BH,期刊:Biochemical and Biophysical Research Communications, 页码:299-305 , 文章类型: Article,,卷期:2011年413-2]
- Acacetin (5.7-dihydroxy-4'-methoxyflavone) is a flavone compound, some of which have anti-cancerous effects. Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis and tumor growth. In this stu...
- Sir-2.1 modulates 'calorie-restriction-mediated' prevention of neurodegeneration in Caenorhabditis elegans: Implications for Parkinson's disease
[作者:Jadiya, P; Chatterjee, M; Sammi, SR; Kaur, S; Palit, G; Nazir, A,期刊:Biochemical and Biophysical Research Communications, 页码:306-310 , 文章类型: Article,,卷期:2011年413-2]
- The phenomenon of aging is known to modulate many disease conditions including neurodegenerative ailments like Parkinson's disease (PD) which is characterized by selective loss of dopaminergic neurons. Recent studies hav...
- The tricyclic antidepressant imipramine induces autophagic cell death in U-87MG glioma cells
[作者:Jeon, SH; Kim, SH; Kim, Y; Kim, YS; Lim, Y; Lee, YH; Shin, SY,期刊:Biochemical and Biophysical Research Communications, 页码:311-317 , 文章类型: Article,,卷期:2011年413-2]
- In this study, we investigated the antitumor effects of the tricyclic antidepressant 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine (imipramine) on glioma cells. We found that exposure of U-87MG ...
- Role of metabolism by the human intestinal microflora in arbutin-induced cytotoxicity in HepG2 cell cultures
[作者:Khanal, T; Kim, HG; Hwang, YP; Kong, MJ; Kang, MJ; Yeo, HK; Kim, DH; Jeong, TC; Jeong, HG,期刊:Biochemical and Biophysical Research Communications, 页码:318-324 , 文章类型: Article,,卷期:2011年413-2]
- A possible role for metabolism by the human intestinal microflora in arbutin-induced cytotoxicity was investigated using human hepatoma HepG2 cells. When the cytotoxic effects of arbutin and hydroquinone (HQ), a deglycos...
- The MUC4 membrane-bound mucin regulates esophageal cancer cell proliferation and migration properties: Implication for S100A4 protein
[作者:Bruyere, E; Jonckheere, N; Frenois, F; Mariette, C; Van Seuningen, I,期刊:Biochemical and Biophysical Research Communications, 页码:325-329 , 文章类型: Article,,卷期:2011年413-2]
- MUC4 is a membrane-bound mucin known to participate in tumor progression. It has been shown that MUC4 pattern of expression is modified during esophageal carcinogenesis, with a progressive increase from metaplastic lesio...
- Regular exercise prevents high-sucrose diet-induced fatty liver via improvement of hepatic lipid metabolism
[作者:Aoi, W; Naito, Y; Hang, LP; Uchiyama, K; Akagiri, S; Mizushima, K; Yoshikawa, T,期刊:Biochemical and Biophysical Research Communications, 页码:330-335 , 文章类型: Article,,卷期:2011年413-2]
- Fatty liver is known as the initial stage in nonalcoholic fatty liver disease. Epidemiological studies have shown that regular exercise prevents accumulation of hepatic lipids, although the underlying mechanism is unclea...
- Identification of the site of binding of sulfated, low molecular weight lignins on thrombin
[作者:Aziz, MHA; Mosier, PD; Desai, UR,期刊:Biochemical and Biophysical Research Communications, 页码:348-352 , 文章类型: Article,,卷期:2011年413-2]
- Sulfated, low molecular weight lignins (LMWLs), designed recently as macromolecular mimetics of the low molecular weight heparins (LMWHs), were found to exhibit a novel allosteric mechanism of inhibition of human thrombi...
- Mesenchymal stem cell marker Stro-1 is a 75kd endothelial antigen
[作者:Ning, HX; Lin, GT; Lue, T; Lin, CS,期刊:Biochemical and Biophysical Research Communications, 页码:353-357 , 文章类型: Article,,卷期:2011年413-2]
- Stro-1 is the best-known mesenchymal stem cell (MSC) marker. However, previous studies have observed its expression in the endothelium. In the present study we performed immunofluorescence (IF) staining for Stro-1, using...
- Cell death induced by novel procaspase-3 activators can be reduced by growth factors
[作者:Debernard, KAB; Aziz, G; Gjesvik, AT; Paulsen, RE,期刊:Biochemical and Biophysical Research Communications, 页码:364-369 , 文章类型: Article,,卷期:2011年413-2]
- Caspase-3 is known as the key executioner caspase, activated in both the intrinsic and extrinsic apoptotic pathway, and an effector far downstream in the apoptotic cascade. Procaspase-activating compound-1 (PAC-1) and 15...
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