- Blocking of CCR5 and CXCR3 Suppresses the Infiltration of Macrophages in Acute Renal Allograft Rejection
[作者:Kakuta, Y; Okumi, M; Miyagawa, S; Tsutahara, K; Abe, T; Yazawa, K; Matsunami, K; Otsuka, H; Takahara, S; Nonomura, N,期刊:Transplantation, 页码:24-31 , 文章类型: Article,,卷期:2012年93-1]
- Background. The chemokine receptors CCR5 and CXCR3 are expressed by T cells and macrophages. We examined effects of a CCR5/CXCR3 antagonist (TAK), with a particular focus on the role of macrophages, in a rat kidney trans...
- Assessment of Batch to Batch Variation in Polyclonal Antithymocyte Globulin Preparations
[作者:Popow, I; Leitner, J; Majdic, O; Kovarik, JJ; Saemann, MD; Zlabinger, GJ; Steinberger, P,期刊:Transplantation, 页码:32-40 , 文章类型: Article,,卷期:2012年93-1]
- Background. Antithymocyte globulins (ATGs) are used to prevent and treat allograft rejection and graft versus host disease. They are purified IgG fractions derived from rabbits immunized with the Jurkat T-cell line (ATG-...
- Early Subclinical Rejection as a Risk Factor for Late Chronic Humoral Rejection
[作者:Moreso, F; Carrera, M; Goma, M; Hueso, M; Sellares, J; Martorell, J; Grinyo, JM; Seron, D,期刊:Transplantation, 页码:41-46 , 文章类型: Article,,卷期:2012年93-1]
- Background. Subclinical rejection and interstitial fibrosis and tubular atrophy (IF/TA) in protocol biopsies are associated with outcome. We study the relationship between histologic lesions in early protocol biopsies an...
- Impact of Early Conversion From Tacrolimus to Sirolimus on Chronic Allograft Changes in Kidney Recipients on Rapid Steroid Withdrawal
[作者:Heilman, RL; Cortese, C; Geiger, XJ; Younan, K; Wadei, HM; Mai, ML; Reddy, KS; Gonwa, TA,期刊:Transplantation, 页码:47-53 , 文章类型: Article,,卷期:2012年93-1]
- Background. Calcineurin-inhibitor therapy is a contributing factor to the origin of interstitial fibrosis and tubular atrophy (IFTA). Methods. We conducted a prospective randomized trial of conversion of tacrolimus to si...
- Mean Arterial Blood Pressure While Awaiting Kidney Transplantation Is Associated With the Risk of Primary Nonfunction
[作者:Webber, A; Hambleton, J; Chami, A; Bang, H; Seshan, S; Sharma, A; August, P; Kapur, S; Suthanthiran, M; Dadhania, D,期刊:Transplantation, 页码:54-60 , 文章类型: Article,,卷期:2012年93-1]
- Background. Primary nonfunction (PNF) is a devastating outcome after kidney transplantation and is more common with kidneys from donors without a heartbeat or expanded criteria donors, or both. We investigated recipient-...
- Valganciclovir Prophylaxis Versus Preemptive Therapy in Cytomegalovirus-Positive Renal Allograft Recipients: 1-Year Results of a Randomized Clinical Trial
[作者:Witzke, O; Hauser, IA; Bartels, M; Wolf, G; Wolters, H; Nitschke, M,期刊:Transplantation, 页码:61-68 , 文章类型: Article,,卷期:2012年93-1]
- Background. Cytomegalovirus (CMV) prevention can be achieved by prophylaxis or preemptive therapy. We performed a prospective randomized trial to determine whether renal transplant recipients with a positive CMV serostat...
- Morbimortality of Pandemic Influenza A H1N1 Infection in Kidney Transplant Recipients Requiring Hospitalization: A Comparative Analysis With Nonimmunocompromised Patients
[作者:Camargo, LFA; de Sandes-Freitas, TV; Silva, CDR; Bittante, CD; Ono, G; Correa, L; Silva, M; Bellei, NCJ; Goto, JM; Medeiros, EAS; Gomes, PS; Medina-Pestana, JO,期刊:Transplantation, 页码:69-72 , 文章类型: Article,,卷期:2012年93-1]
- Background. Clinical and epidemiological data of pandemic influenza A H1N1 infection in solid-organ transplant recipients have been described, but scarce data compare these outcomes with nonimmunocompromised patients. Me...
- Incidence, Diagnosis, and Treatment of Chylous Leakage After Laparoscopic Live Donor Nephrectomy
[作者:Capocasale, E; Iaria, M; Vistoli, F; Signori, S; Mazzoni, MP; Dalla Valle, R; De Lio, N; Perrone, V; Amorese, G; Mosca, F; Boggi, U,期刊:Transplantation, 页码:82-86 , 文章类型: Article,,卷期:2012年93-1]
- Background. Chylous leakage (CL) is a rare complication of laparoscopic live donor nephrectomy (LLDN). It may lead to malnutrition and immunological deficits because of protein and lymphocyte depletion. Methods. Data fro...
- Desensitization With Antigen-Specific Immunoadsorption Interferes With Complement in ABO-Incompatible Kidney Transplantation
[作者:Biglarnia, AR; Nilsson, B; Ekdahl, KN; Tufveson, G; Nilsson, T; Larsson, E; Wadstrom, J,期刊:Transplantation, 页码:87-92 , 文章类型: Article,,卷期:2012年93-1]
- Background. Complement activation was characterized during and after desensitization treatment in 19 consecutive patients receiving ABO-incompatible (ABOi) living donor kidney transplants to assess the effect of desensit...
- Risk Factors That Increase Mortality After Living Donor Liver Transplantation
[作者:Yoshizumi, T; Shirabe, K; Taketomi, A; Uchiyama, H; Harada, N; Ijichi, H; Yoshimatsu, M; Ikegami, T; Soejima, Y; Maehara, Y,期刊:Transplantation, 页码:93-98 , 文章类型: Article,,卷期:2012年93-1]
- Background. Female liver to male recipient is a well-accepted risk factor for graft loss in cadaveric liver transplantation. However, gender matching is infeasible because of an insufficient number of available donors. N...
- Splenectomy Does Not Offer Immunological Benefits in ABO-Incompatible Liver Transplantation With a Preoperative Rituximab
[作者:Raut, V; Mori, A; Kaido, T; Ogura, Y; Taku, I; Nagai, K; Sasaki, N; Endo, K; Hata, T; Yagi, S; Egawa, H; Uemoto, S,期刊:Transplantation, 页码:99-105 , 文章类型: Article,,卷期:2012年93-1]
- Background. Preformed anti-ABO antibodies are primarily responsible for antibody-mediated rejection (AMR) after ABO-incompatible (ABO-I) liver transplantation (LT) resulting in lethal hepatic necrosis and biliary complic...
- Mechanisms of Rejection: Current Perspectives
[作者:Wood, KJ; Goto, R,期刊:Transplantation, 页码:1-10 , 文章类型: Review,,卷期:2012年93-1]
- Rejection is the major barrier to successful transplantation. The immune response to an allograft is an ongoing dialogue between the innate and adaptive immune system that if left unchecked will lead to the rejection of ...
- Influence of Metabolic Syndrome on Development of Cardiac Allograft Vasculopathy in the Transplanted Heart
[作者:Sanchez-Gomez, JM; Martinez-Dolz, L; Sanchez-Lazaro, I; Almenar, L; Sanchez-Lacuesta, E; Munoz-Giner, B; Portoles, M; Rivera, M; Valera-Roman, A; Gonzalez-Juanatey, JR; Tejada-Ponce, D; Aguero, J; Buendia, F; Salvador, A,期刊:Transplantation, 页码:106-111 , 文章类型: Article,,卷期:2012年93-1]
- Background. Cardiac allograft vasculopathy (CAV) is the main cause of graft failure and death 1 year after heart transplantation (HTx). Metabolic syndrome (MS) increases the risk of cardiovascular events by endothelial d...
- Kinetics of T-Lymphocyte Subsets and Posttransplant Opportunistic Infections in Heart and Kidney Transplant Recipients
[作者:Calarota, SA; Zelini, P; De Silvestri, A; Chiesa, A; Comolli, G; Sarchi, E; Migotto, C; Pellegrini, C; Esposito, P; Minoli, L; Tinelli, C; Marone, P; Baldanti, F,期刊:Transplantation, 页码:112-119 , 文章类型: Article,,卷期:2012年93-1]
- Background. The potential use of T-lymphocyte measurements as infection risk markers after solid organ transplant has not been fully investigated. We analyzed the kinetics of T-lymphocyte subsets within the first 8 month...
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