- Associations Between Features of Glucose Exposure and A1C The A1C-Derived Average Glucose (ADAG) Study
[作者：Borg, R; Kuenen, JC; Carstensen, B; Zheng, H; Nathan, DM; Heine, RJ; Nerup, J; Borch-Johnsen, K; Witte, DR,期刊：Diabetes, 页码：1585-1590 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE-Various methods are used to quantify postprandial glycemia or glucose variability, but few have been compared and none are standardized. Our objective was to examine the relationship among common indexes of pos...
- Lipoprotein Subfraction Cholesterol Distribution Is Proatherogenic in Women With Type 1 Diabetes and Insulin Resistance
[作者：Maahs, DM; Hokanson, JE; Wang, H; Kinney, GL; Snell-Bergeon, JK; East, A; Bergman, BC; Schauer, IE; Rewers, M; Eckel, RH,期刊：Diabetes, 页码：1771-1779 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE Individuals with type 1 diabetes have a less atherogenic fasting lipid profile than those without diabetes but paradoxically have increased rates of cardiovascular disease (CVD). We investigated differences in ...
- Profile of Lipid and Protein Autacoids in Diabetic Vitreous Correlates With the Progression of Diabetic Retinopathy
[作者：Schwartzman, ML; Iserovich, P; Gotlinger, K; Bellner, L; Dunn, MW; Sartore, M; Pertile, MG; Leonardi, A; Sathe, S; Beaton, A; Trieu, L; Sack, R,期刊：Diabetes, 页码：1780-1788 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE This study was aimed at obtaining a profile of lipids and proteins with a paracrine function in normal and diabetic vitreous and exploring whether the profile correlates with retinal pathology. RESEARCH DESIGN ...
- Pituitary Adenylate Cyclase-Activating Polypeptide Stimulates Glucose Production via the Hepatic Sympathetic Innervation in Rats
[作者：Yi, CX; Sun, N; Ackermans, MT; Alkemade, A; Foppen, E; Shi, J; Serlie, MJ; Buijs, RM; Fliers, E; Kalsbeek, A,期刊：Diabetes, 页码：1591-1600 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE-The unraveling of the elaborate brain networks that control glucose metabolism presents one of the current challenges in diabetes research. Within the central nervous system, the hypothalamus is regarded as the...
- A Prospective Analysis of Elevated Fasting Glucose Levels and Cognitive Function in Older People Results From PROSPER and the Rotterdam Study
[作者：Euser, SM; Sattar, N; Witteman, JCM; Bollen, ELEM; Sijbrands, EJG; Hofman, A; Perry, IJ; Breteler, MMB; Westendorp, RGJ,期刊：Diabetes, 页码：1601-1607 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE-To investigate the relationship between fasting glucose levels, insulin resistance, and cognitive impairment in old age. Diabetes is associated with cognitive impairment in older people. However, the link betwe...
- Impact of Age on the Relationships of Brown Adipose Tissue With Sex and Adiposity in Humans
[作者：Pfannenberg, C; Werner, MK; Ripkens, S; Stef, I; Deckert, A; Schmadl, M; Reimold, M; Haring, HU; Claussen, CD; Stefan, N,期刊：Diabetes, 页码：1789-1793 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE Brown adipose tissue (BAT) regulates energy homeostasis and fat mass in mammals and newborns and, most likely, in adult humans. Because BAT activity and BAT mass decline with age in humans, the impact of BAT on...
- E-Cadherin Expression Is Regulated by miR-1921215 by a Mechanism That Is Independent of the Profibrotic Effects of Transforming Growth Factor-beta
[作者：Wang, B; Herman-Edelstein, M; Koh, P; Burns, W; Jandeleit-Dahm, K; Watson, A; Saleem, M; Goodall, GJ; Twigg, SM; Cooper, ME; Kantharidis, P,期刊：Diabetes, 页码：1794-1802 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE Increased deposition of extracellular matrix (ECM) within the kidney is driven by prolibrotic mediators including transforming growth factor-beta (TGF-beta) and connective tissue growth factor (CTGF). We invest...
- Cumulative Risk, Age at Onset, and Sex-Specific Differences for Developing End-Stage Renal Disease in Young Patients With Type 1 Diabetes A Nationwide Population-Based Cohort Study
[作者：Mollsten, A; Svensson, M; Waernbaum, I; Berhan, Y; Schon, S; Nystrom, L; Arnqvist, HJ; Dahlquist, G,期刊：Diabetes, 页码：1803-1808 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE This study aimed to estimate the current cumulative risk of end-stage renal disease (ESRD) due to diabetic nephropathy in a large, nationwide, population-based prospective type 1 diabetes cohort and specificall...
- Role of KLF15 in Regulation of Hepatic Gluconeogenesis and Metformin Action
[作者：Takashima, M; Ogawa, W; Hayashi, K; Inoue, H; Kinoshita, S; Okamoto, Y; Sakaue, H; Wataoka, Y; Emi, A; Senga, Y; Matsuki, Y; Watanabe, E; Hiramatsu, R; Kasuga, M,期刊：Diabetes, 页码：1608-1615 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE-An increase in the rate of gluconeogenesis is largely responsible for the hyperglycemia in individuals with type 2 diabetes, with the antidiabetes action of metformin being thought to be achieved at least in pa...
- Fibroblast Growth Factor 21 Action in the Brain Increases Energy Expenditure and Insulin Sensitivity in Obese Rats
[作者：Sarruf, DA; Thaler, JP; Morton, GJ; German, J; Fischer, JD; Ogimoto, K; Schwartz, MW,期刊：Diabetes, 页码：1817-1824 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE-The hormone fibroblast growth factor 21 (FGF21) exerts diverse, beneficial effects on energy balance and insulin sensitivity when administered systemically to rodents with diet-induced obesity (DIO). The curren...
- Resveratrol Inhibits Neuronal Apoptosis and Elevated Ca2+/Calmodulin-Dependent Protein Kinase II Activity in Diabetic Mouse Retina
[作者：Kim, YH; Kim, YS; Kang, SS; Cho, GJ; Choi, WS,期刊：Diabetes, 页码：1825-1835 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE This study investigated the effects of resveratrol, a natural polyphenol with neuroprotective properties, on retinal neuronal cell death mediated by diabetes-induced activation of Ca2+/calmodulin-dependent prot...
- Early Hepatic Insulin Resistance Precedes the Onset of Diabetes in Obese C57BLKS-db/db Mice
[作者：Davis, RC; Castellani, LW; Hosseini, M; Ben-Zeev, O; Mao, HZ; Weinstein, MM; Jung, DY; Jun, JY; Kim, JK; Lusis, AJ; Peterfy, M,期刊：Diabetes, 页码：1616-1625 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE-To identify metabolic derangements contributing to diabetes susceptibility in the leptin receptor-deficient obese C57BLKS/J-db/db (BKS-db) mouse strain. RESEARCH DESIGN AND METHODS-Young BKS-db mice were used t...
- Spectrum of HNF1A Somatic Mutations in Hepatocellular Adenoma Differs From That in Patients With MODY3 and Suggests Genotoxic Damage
[作者：Jeannot, E; Mellottee, L; Bioulac-Sage, P; Balabaud, C; Scoazec, JY; Van Nhieu, JT; Bacq, Y; Michalak, S; Buob, D; Laurent-Puig, P; Rusyn, I; Zucman-Rossi, J,期刊：Diabetes, 页码：1836-1844 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE Maturity onset diabetes of the young type 3 (MODY3) is a consequence of heterozygous germline mutation in HNF1A. A subtype of hepatocellular adenoma (HCA) is also caused by biallelic somatic HNF1A mutations (H-...
- Leptin Deficiency Causes Insulin Resistance Induced by Uncontrolled Diabetes
[作者：German, JP; Wisse, BE; Thaler, JP; Oh-I, S; Sarruf, DA; Ogimoto, K; Kaiyala, KJ; Fischer, JD; Matsen, ME; Taborsky, GJ; Schwartz, MW; Morton, GJ,期刊：Diabetes, 页码：1626-1634 , 文章类型： Article，,卷期：2010年59-7]
- OBJECTIVE-Depletion of body fat stores during uncontrolled, insulin-deficient diabetes (uDM) results in markedly reduced plasma leptin levels. This study investigated the role of leptin deficiency in the genesis of sever...
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