- Increased galectin-7 gene expression in lymphoma cells is under the control of DNA methylation
[作者:Demers, M; Couillard, J; Giglia-Mari, G; Magnaldo, T; St-Pierre, Y,期刊:Biochemical and Biophysical Research Communications, 页码:425-429 , 文章类型: Article,,卷期:2009年387-3]
- Recent studies have reported that elevated levels of galectin-7 in different types of cancer. The mechanisms underlying its abnormal regulation in cancer cells remain, however, unknown. Here. we have examined the relatio...
- NADPH oxidase activity in allergenic pollen grains of different plant species
[作者:Wang, XL; Takai, T; Kamijo, S; Gunawan, H; Ogawa, H; Okumura, K,期刊:Biochemical and Biophysical Research Communications, 页码:430-434 , 文章类型: Article,,卷期:2009年387-3]
- Pollen is an important trigger of allergic diseases. Recent studies have shown that ragweed pollen NAD(P)H oxidase generates reactive oxygen species (RCS) and plays a prominent role in the pathogenesis of allergies in mo...
- Peritoneal injection of fucoidan suppresses the increase of plasma IgE induced by OVA-sensitization
[作者:Yanase, Y; Hiragun, T; Uchida, K; Ishii, K; Oomizu, S; Suzuki, H; Mihara, S; Iwamoto, K; Matsuo, H; Onishi, N; Kameyoshi, Y; Hide, M,期刊:Biochemical and Biophysical Research Communications, 页码:435-439 , 文章类型: Article,,卷期:2009年387-3]
- We previously reported that fucoidan, a dietary fiber purified from seaweed, inhibited IgE production by B cells in vitro. In this study, we examined the effect of fucoidan on IgE production in vivo. The OVA-induced incr...
- Isoreserpine promotes beta-catenin degradation via Siah-1 up-regulation in HCT116 colon cancer cells
[作者:Gwak, J; Song, T; Song, JY; Yun, YS; Choi, IW; Jeong, Y; Shin, JG; Oh, S,期刊:Biochemical and Biophysical Research Communications, 页码:444-449 , 文章类型: Article,,卷期:2009年387-3]
- Aberrant accumulation of intracellular beta-catenin in intestinal epithelial cells is a frequent early event during the development of colon cancer. To identify small molecules that decrease the level of intracellular be...
- SP600125, an inhibitor of Jnk pathway, reduces viability of relatively resistant cancer cells to doxorubicin
[作者:Kim, JH; Kim, TH; Kang, HS; Ro, J; Kim, HS; Yoon, S,期刊:Biochemical and Biophysical Research Communications, 页码:450-455 , 文章类型: Article,,卷期:2009年387-3]
- We identified four breast cancer cell lines and one stomach cancer cell line resistant to the cytotoxic effects of doxorubicin (DOX) and examined their sensitivity to other chemotherapeutic agents. SP600125, an inhibitor...
- Evidences showing association of interleukin-1B polymorphisms with increased risk of gastric cancer in an Indian population
[作者:Kumar, S; Kumar, A; Dixit, VK,期刊:Biochemical and Biophysical Research Communications, 页码:456-460 , 文章类型: Article,,卷期:2009年387-3]
- Helicobacter pylon infection is strongly associated with gastric cancer. In the present study, the relationship between interleukin-1B (IL-1B) polymorphism, H. pylori infection, and prevalence of gastric cancer (CC) in p...
- Polyglutamine expansion in huntingtin increases its insertion into lipid bilayers
[作者:Kegel, KB; Schewkunow, V; Sapp, E; Masso, N; Wanker, EE; DiFiglia, M; Goldmann, WH,期刊:Biochemical and Biophysical Research Communications, 页码:472-475 , 文章类型: Article,,卷期:2009年387-3]
- An expanded polyglutamine (Q) tract (>37Q) in huntingtin (htt) causes Huntington disease. Htt associates with membranes and polyglutamine expansion in htt may alter membrane function in Huntington disease through a mecha...
- An six-amino acid motif in the alpha 3 domain of MICA is the cancer therapeutic target to inhibit shedding
[作者:Wang, XJ; Lundgren, AD; Singh, P; Goodlett, DR; Plymate, SR; Wu, JD,期刊:Biochemical and Biophysical Research Communications, 页码:476-481 , 文章类型: Article,,卷期:2009年387-3]
- Expression of the MHC class I chain related molecules A and B (MICA/B) on tumor cell surface can signal the immune receptor NKG2D for tumor immune destruction. However, MIC was found to be shed by tumors in cancer patien...
- The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells
[作者:Yokoo, N; Baba, S; Kaichi, S; Niwa, A; Mima, T; Doi, H; Yamanaka, S; Nakahata, T; Heike, T,期刊:Biochemical and Biophysical Research Communications, 页码:482-488 , 文章类型: Article,,卷期:2009年387-3]
- Developing effective drug therapies for arrhythmic diseases is hampered by the fact that the same drug can work well in some individuals but not in others. Human induced pluripotent stem (iPS) cells have been vetted as u...
- Hepatitis C virus is restricted at both entry and replication in mouse hepatocytes
[作者:Park, IW; Ndjomou, J; Fan, Y; Henao-Mejia, J; He, JJ,期刊:Biochemical and Biophysical Research Communications, 页码:489-493 , 文章类型: Article,,卷期:2009年387-3]
- Human hepatitis C Virus (HCV) does not replicate ill mouse hepatocytes. The underlying mechanisms are largely unknown. In this study, we took advantage of a series of direct and unique molecular strategies and dissected ...
- SUMO modification regulates the transcriptional activity of FLASH
[作者:Alm-Kristiansen, AH; Norman, IL; Matre, V; Gabrielsen, OS,期刊:Biochemical and Biophysical Research Communications, 页码:494-499 , 文章类型: Article,,卷期:2009年387-3]
- FLASH is a huge multifunctional nuclear protein that has been linked to apoptotic signalling, transcriptional control and Cajal body function. To gain further insight into the functions of the FLASH protein, we performed...
- CRELD2 is a novel endoplasmic reticulum stress-inducible gene
[作者:Oh-hashi, K; Koga, H; Ikeda, S; Shimada, K; Hirata, Y; Kiuchi, K,期刊:Biochemical and Biophysical Research Communications, 页码:504-510 , 文章类型: Article,,卷期:2009年387-3]
- Recently, endoplasmic reticulum (ER) Stress responses have been suggested to play important roles in maintaining various cellular functions and to underlie many tissue dysfunctions. In this study, we first identified cys...
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