- The role of the histone H2A ubiquitinase Sce in Polycomb repression
[作者：Gutierrez, L; Oktaba, K; Scheuermann, JC; Gambetta, MC; Ly-Hartig, N; Muller, J,期刊：Development, 页码：117-127 , 文章类型： Article，,卷期：2012年139-1]
- Polycomb group (PcG) proteins exist in multiprotein complexes that modify chromatin to repress transcription. Drosophila PcG proteins Sex combs extra (Sce; dRing) and Posterior sex combs (Psc) are core subunits of PRC1-t...
- Differential plasticity of epiblast and primitive endoderm precursors within the ICM of the early mouse embryo
[作者：Grabarek, JB; Zyzynska, K; Saiz, N; Piliszek, A; Frankenberg, S; Nichols, J; Hadjantonakis, AK; Plusa, B,期刊：Development, 页码：129-139 , 文章类型： Article，,卷期：2012年139-1]
- Cell differentiation during pre-implantation mammalian development involves the formation of two extra-embryonic lineages: trophoblast and primitive endoderm (PrE). A subset of cells within the inner cell mass (ICM) of t...
- Rankl-induced osteoclastogenesis leads to loss of mineralization in a medaka osteoporosis model
[作者：To, TT; Witten, PE; Renn, J; Bhattacharya, D; Huysseune, A; Winkler, C,期刊：Development, 页码：141-150 , 文章类型： Article，,卷期：2012年139-1]
- Osteoclasts are macrophage-related bone resorbing cells of hematopoietic origin. Factors that regulate osteoclastogenesis are of great interest for investigating the pathology and treatment of bone diseases such as osteo...
- Epigenetic reprogramming in mouse pre-implantation development and primordial germ cells
[作者：Saitou, M; Kagiwada, S; Kurimoto, K,期刊：Development, 页码：15-31 , 文章类型： Review，,卷期：2012年139-1]
- Epigenetic modifications are crucial for the identity and stability of cells, and, when aberrant, can lead to disease. During mouse development, the genome-wide epigenetic states of pre-implantation embryos and primordia...
- Sox2-mediated differential activation of Six3.2 contributes to forebrain patterning
[作者：Beccari, L; Conte, I; Cisneros, E; Bovolenta, P,期刊：Development, 页码：151-164 , 文章类型： Article，,卷期：2012年139-1]
- The vertebrate forebrain is patterned during gastrulation into telencephalic, retinal, hypothalamic and diencephalic primordia. Specification of each of these domains requires the concerted activity of combinations of tr...
- Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program
[作者：Stam, FJ; Hendricks, TJ; Zhang, JM; Geiman, EJ; Francius, C; Labosky, PA; Clotman, F; Goulding, M,期刊：Development, 页码：179-190 , 文章类型： Article，,卷期：2012年139-1]
- The spinal cord contains a diverse array of physiologically distinct interneuron cell types that subserve specialized roles in somatosensory perception and motor control. The mechanisms that generate these specialized in...
- miR-200c regulates FGFR-dependent epithelial proliferation via Vldlr during submandibular gland branching morphogenesis
[作者：Rebustini, IT; Hayashi, T; Reynolds, AD; Dillard, ML; Carpenter, EM; Hoffman, MP,期刊：Development, 页码：191-202 , 文章类型： Article，,卷期：2012年139-1]
- The regulation of epithelial proliferation during organ morphogenesis is crucial for normal development, as dysregulation is associated with tumor formation. Non-coding microRNAs (miRNAs), such as miR-200c, are post-tran...
- Engrailed homeoprotein recruits the adenosine A1 receptor to potentiate ephrin A5 function in retinal growth cones
[作者：Stettler, O; Joshi, RL; Wizenmann, A; Reingruber, J; Holcman, D; Bouillot, C; Castagner, F; Prochiantz, A; Moya, KL,期刊：Development, 页码：215-224 , 文章类型： Article，,卷期：2012年139-1]
- Engrailed 1 and engrailed 2 homeoprotein transcription factors (collectively Engrailed) display graded expression in the chick optic tectum where they participate in retino-tectal patterning. In vitro, extracellular Engr...
- Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism
[作者：Ahnfelt-Ronne, J; Jorgensen, MC; Klinck, R; Jensen, JN; Fuchtbauer, EM; Deering, T; MacDonald, RJ; Wright, CVE; Madsen, OD; Serup, P,期刊：Development, 页码：33-45 , 文章类型： Article，,卷期：2012年139-1]
- Neurog3-induced Dll1 expression in pancreatic endocrine progenitors ostensibly activates Hes1 expression via Notch and thereby represses Neurog3 and endocrine differentiation in neighboring cells by lateral inhibition. H...
- A model of stem cell population dynamics: in silico analysis and in vivo validation
[作者：Setty, Y; Dalfo, D; Korta, DZ; Hubbard, EJA; Kugler, H,期刊：Development, 页码：47-56 , 文章类型： Article，,卷期：2012年139-1]
- The proper renewal and maintenance of tissues by stem cell populations is simultaneously influenced by anatomical constraints, cell proliferation dynamics and cell fate specification. However, their relative influence is...
- G beta gamma signaling controls the polarization of zebrafish primordial germ cells by regulating Rac activity
[作者：Xu, H; Kardash, E; Chen, SH; Raz, E; Lin, F,期刊：Development, 页码：57-62 , 文章类型： Article，,卷期：2012年139-1]
- During development, primordial germ cells (PGCs) migrate from the sites of their specification towards the region in which the future gonad develops. This cell migration requires polarization of PGCs and their responsive...
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