- Putative function of TAP63 alpha during endochondral bone formation
[作者:Li, FF; Lu, YJ; Ding, M; Wu, GJ; Sinha, S; Wang, SY; Zheng, QP,期刊:Gene, 页码:95-103 , 文章类型: Article,,卷期:2012年495-2]
- P63, a member of the P53 tumor suppressor family, is known to play important functions in cancer and development. Interestingly, previous studies have shown that p63 null mice are absent or have truncated limbs, while mu...
- Differential requirement for the N-terminal catalytic domain of the DNA polymerase epsilon p255 subunit in the mitotic cell cycle and the endocycle
[作者:Suyari, O; Kawai, M; Ida, H; Yoshida, H; Sakaguchi, K; Yamaguchi, M,期刊:Gene, 页码:104-114 , 文章类型: Article,,卷期:2012年495-2]
- In Drosophila, the 255 kDa catalytic subunit (dpol epsilon p255) and the 58 kDa subunit of DNA polymerase epsilon (dpol epsilon p58) have been identified. The N-terminus of dpol epsilon p255 carries well-conserved six DN...
- Genetic variants of TCF7L2 are associated with type 2 diabetes in a northeastern Chinese population
[作者:Qiao, H; Zhang, XL; Zhao, XD; Zhao, YL; Xu, LD; Sun, HM; Fu, SB,期刊:Gene, 页码:115-119 , 文章类型: Article,,卷期:2012年495-2]
- Variants in the gene encoding transcription factor 7-like 2 (TCF7L2) are associated with type 2 diabetes mellitus (T2D) in several ethnic groups. Two intronic variants, rs290487 and rs11196218, were originally identified...
- Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells
[作者:Liu, DZ; Ander, BP; Tian, YF; Stamova, B; Jickling, GC; Davis, RR; Sharp, FR,期刊:Gene, 页码:120-127 , 文章类型: Article,,卷期:2012年495-2]
- Mature neurons (MNs), neural progenitor cells (NPCs) and neuroblastoma cells (NBCs) are all neural-derived cells. However, MNs are unable to divide once differentiated; NPCs are able to divide a limited number of times a...
- The soybean aldehyde dehydrogenase (ALDH) protein superfamily
[作者:Kotchoni, SO; Jimenez-Lopez, JC; Kayode, APP; Gachomo, EW; Baba-Moussa, L,期刊:Gene, 页码:128-133 , 文章类型: Article,,卷期:2012年495-2]
- Aldehyde dehydrogenases (ALDHs) are members of NAD(P)(+)-dependent protein superfamily that catalyze the oxidation of a wide range of endogenous and exogenous highly reactive aliphatic and aromatic aldehyde molecules to ...
- Delayed death phenomenon: A synergistic action of cyclophosphamide and exogenous DNA
[作者:Dolgova, EV; Proskurina, AS; Nikolin, VP; Popova, NA; Alyamkina, EA; Orishchenko, KE; Rogachev, VA; Efremov, YR; Dubatolova, TD; Prokopenko, AV; Chernykh, ER; Ostanin, AA; Taranov, OS; Omigov, VV; Zagrebelniy, SN; Bogachev, SS; Shurdov, MA,期刊:Gene, 页码:134-145 , 文章类型: Article,,卷期:2012年495-2]
- Morbidity and mortality in mice were observed upon administration of exogenous DNA following their pretreatment with a cytostatic agent cyclophosphamide. Upon intraperitoneal injections, the fragments of exogenous DNA re...
- ZmRFP1, the putative ortholog of SDIR1, encodes a RING-H2 E3 ubiquitin ligase and responds to drought stress in an ABA-dependent manner in maize
[作者:Xia, ZL; Liu, QJ; Wu, JY; Ding, JQ,期刊:Gene, 页码:146-153 , 文章类型: Article,,卷期:2012年495-2]
- Drought is one of the most important limiting factors in crop production. To identify genes required for the drought stress response in the cereal crop maize, a gene coding for RING-finger protein (ZmRFP1), which is high...
- Properties of the inulinase gene levH1 of Lactobacillus casei IAM 1045; cloning, mutational and biochemical characterization
[作者:Kuzuwa, S; Yokoi, K; Kondo, M; Kimoto, H; Yamakawa, A; Taketo, A; Kodaira, KI,期刊:Gene, 页码:154-162 , 文章类型: Article,,卷期:2012年495-2]
- Though some genetic features of lactobacillar fructan hydrolases were elucidated, information about their enzymology or mutational analyses were scarce. Lactobacillus casei IAM1045 exhibits extracellular activity degradi...
- High resolution array in the clinical approach to chromosomal phenotypes
[作者:Filges, I; Suda, L; Weber, P; Datta, AN; Fischer, D; Dill, P; Glanzmann, R; Benzing, J; Hegi, L; Wenzel, F; Huber, AR; Mori, AC; Miny, P; Rothlisberger, B,期刊:Gene, 页码:163-169 , 文章类型: Article,,卷期:2012年495-2]
- Array genomic hybridization (AGH) has recently been implemented as a diagnostic tool for the detection of submicroscopic copy number variants (CNVs) in patients with developmental disorders. However, there is no consensu...
- Molecular cloning, tissue expression and protein structure prediction of the porcine 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR) gene
[作者:Chen, X; Wang, XF; Li, ZJ; Kong, LJ; Liu, GF; Fu, JL; Wang, AG,期刊:Gene, 页码:170-177 , 文章类型: Article,,卷期:2012年495-2]
- 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (HMGR) is the rate-limiting enzyme for cholesterol synthesis. Its activity is regulated via a negative feedback mechanism through sterols and non-sterol metabolites derived...
- Prenatal diagnosis of a fetus with a de novo trisomy 12p by array-comparative genomic hybridization (array-CGH)
[作者:Hung, CC; Lin, CH; Lin, SY; Shin, JC; Lee, CN; Su, YN,期刊:Gene, 页码:178-182 , 文章类型: Article,,卷期:2012年495-2]
- Trisomy 12p syndrome is a rare chromosomal abnormality, which presents with facial dysmorphism, moderate to severe psychomotor retardation and generalized hypotonia. Here we present the prenatal sonographic findings inve...
- BsmI polymorphisms in vitamin D receptor gene are associated with diabetic nephropathy in type 2 diabetes in the Han Chinese population
[作者:Zhang, H; Wang, JW; Yi, B; Zhao, Y; Liu, Y; Zhang, K; Cai, X; Sun, J; Huang, LH; Liao, Q,期刊:Gene, 页码:183-188 , 文章类型: Article,,卷期:2012年495-2]
- We investigated the relationship between BsmI/ApaI polymorphisms in vitamin D receptor gene and diabetic nephropathy in a Han Chinese population. PCR-restriction fragment length polymorphism was used to test the genotype...
- Nanostructure and beta 1-integrin distribution analysis of pig's spermatogonial stem cell by atomic force microscopy
[作者:Li, SP; Shi, RY; Wang, QL; Cai, JY; Zhang, SQ,期刊:Gene, 页码:189-193 , 文章类型: Article,,卷期:2012年495-2]
- Spermatogonial stem cells (SSCs) provide the foundation for spermatogenesis and male fertility. However, spermatogenesis has direct links with some adhesion molecules on SSCs membrane. B1-integrin (CD29) is such a kind o...
- Associations of variants of CNR1 with obesity and obesity-related traits in Chinese women
[作者:Zhuang, MQ; Yang, YJ; Cao, FF; Lu, M; Wang, XF; Zhang, J; Chen, XD; Cheng, P; Zhang, NN; Ye, WM; Jin, L,期刊:Gene, 页码:194-198 , 文章类型: Article,,卷期:2012年495-2]
- The aim of this study was to investigate associations of two candidate gene SNPs of the endocannabinoid receptor type 1 gene (CNR1) with overweight, obesity and obesity-related traits in Chinese retired women. The study ...
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