- Effect of fractalkine-Fc delivery in experimental lung metastasis using DNA/704 nanospheres
[作者:Richard-Fiardo, P; Cambien, B; Pradelli, E; Beilvert, F; Pitard, B; Schmid-Antomarchi, H; Schmid-Alliana, A,期刊:Cancer gene therapy, 页码:761-772 , 文章类型: Article,,卷期:2011年18-11]
- The lung is one target organ to which solid tumors frequently metastasize. Given the systemic adverse effects of currently available treatments, developing effective strategies of drug/gene delivery directly to the lungs...
- Adenovirus-mediated hypoxia-targeted gene therapy using HSV thymidine kinase and bacterial nitroreductase prodrug-activating genes in vitro and in vivo
[作者:Harvey, TJ; Hennig, IM; Shnyder, SD; Cooper, PA; Ingram, N; Hall, GD; Selby, PJ; Chester, JD,期刊:Cancer gene therapy, 页码:773-784 , 文章类型: Article,,卷期:2011年18-11]
- Hypoxia is an important factor in tumor growth. It is associated with resistance to conventional anticancer treatments. Gene therapy targeting hypoxic tumor cells therefore has the potential to enhance the efficacy of tr...
- Influence of osteopontin expression on the metastatic growth of CC531 rat colorectal carcinoma cells in rat liver
[作者:Uhlmann, ME; Georges, RB; Boleij, A; Eyol, E; Kubarenko, A; Adwan, H; Berger, MR,期刊:Cancer gene therapy, 页码:795-805 , 文章类型: Article,,卷期:2011年18-11]
- Development of hepatic metastasis is responsible for most of colorectal cancer-related deaths. Osteopontin (OPN) is a small integrin-binding N-linked glycoprotein, which plays a crucial role in the formation of hepatic m...
- Therapeutic targeting of subdural medulloblastomas using human neural stem cells expressing carboxylesterase
[作者:Lim, SH; Choi, SA; Lee, JY; Wang, KC; Phi, JH; Lee, DH; Song, SH; Song, JH; Jin, X; Kim, H; Lee, HJ; Lim, I; Kim, SU; Kim, SK,期刊:Cancer gene therapy, 页码:817-824 , 文章类型: Article,,卷期:2011年18-11]
- The prognosis of medulloblastoma has improved significantly because of advances in multi-modal treatments; however, metastasis remains one of the prognostic factors for a poor outcome and is usually associated with tumor...
- Oncolytic adenovirus armed with human papillomavirus E2 gene in combination with radiation demonstrates synergistic enhancements of antitumor efficacy
[作者:Wang, W; Xia, X; Wang, S; Sima, N; Li, Y; Han, Z; Gao, Q; Luo, A; Li, K; Meng, L; Zhou, J; Wang, C; Shen, K; Ma, D,期刊:Cancer gene therapy, 页码:825-836 , 文章类型: Article,,卷期:2011年18-11]
- High-risk human papillomavirus (hr-HPV) E6 and E7 oncogenes are associated with resistance to radiotherapy in cervical cancer. Efforts have been taken to employ HPV E2, a crucial negative transcriptional modulator of HPV...
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