- Core promoter STRs: Novel mechanism for inter-individual variation in gene expression in humans
[作者:Heidari, A; Fam, ZNS; Esmaeilzadeh-Gharehdaghi, E; Banan, M; Hosseinkhani, S; Mohammadparast, S; Oladnabi, M; Ebrahimpour, MR; Soosanabadi, M; Farokhashtiani, T; Darvish, H; Firouzabadi, SG; Farashi, S; Najmabadi, H; Ohadi, M,期刊:Gene, 页码:195-198 , 文章类型: Article,,卷期:2012年492-1]
- In a genome-scale analysis of the composition of core promoter sequences, we have recently shown that approximately 25% of the human protein-coding genes have at least one short tandem repeat (STR) of 3-repeats in their ...
- 1 kbp 5 ' upstream sequence enables developmental stage-specific expressions of globin genes in the fish, medaka Oryzias latipes
[作者:Maruyama, K; Wang, B; Ishikawa, Y; Yasumasu, S; Iuchi, I,期刊:Gene, 页码:212-219 , 文章类型: Article,,卷期:2012年492-1]
- Hemoglobin of bony fish and higher vertebrates is a tetrameric protein constructed by 2 alpha- and 2 beta-globins, which are expressed in a developmental stage-specific manner. The genomic organization of genes for embry...
- Identification and characterization of low temperature stress responsive genes in Poncirus trifoliata by suppression subtractive hybridization
[作者:Peng, T; Zhu, XF; Fan, QJ; Sun, PP; Liu, JH,期刊:Gene, 页码:220-228 , 文章类型: Article,,卷期:2012年492-1]
- Trifoliate orange (Poncirus trifoliata (L) Raf.) is extremely cold hardy when fully acclimated, but knowledge relevant to the molecular events underlying the acclimation is still limited so far. In this study, forward (4...
- METCAM/MUC18 augments migration, invasion, and tumorigenicity of human breast cancer SK-BR-3 cells
[作者:Zeng, GF; Cai, SX; Liu, Y; Wu, GJ,期刊:Gene, 页码:229-238 , 文章类型: Article,,卷期:2012年492-1]
- Previous research has identified METCAM/MUC18, an integral membrane cell adhesion molecule (CAM) in the Ig-like gene super-family, as a promoter or a suppressor in the development of human breast cancer by MCF7, MDA-MB-2...
- Identification and functional characterization of novel compound heterozygotic mutations in the TECTA gene
[作者:Sagong, B; Park, HJ; Lee, KY; Kim, UK,期刊:Gene, 页码:239-243 , 文章类型: Article,,卷期:2012年492-1]
- Mutations of the TECTA gene, which encodes alpha-tectorin, are associated with both dominant (DFNA8/A12) and recessive (DFNB 21) modes of inherited nonsyndromic sensorineural hearing loss, respectively. Although clinical...
- Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): Evidence for extremely low lysozyme levels in emu egg white
[作者:Maehashi, K; Matano, M; Irisawa, T; Uchino, M; Kashiwagi, Y; Watanabe, T,期刊:Gene, 页码:244-249 , 文章类型: Article,,卷期:2012年492-1]
- Lysozyme (LZ), a bacteriolytic enzyme, is found in the egg white of many avian eggs and plays an important role in host defense; however, LZ activity in emu (Dromaius novaehollandiae) egg white is exceptionally undetecta...
- Comparative expression analysis in mature gonads, liver and brain of turbot (Scophthalmus maximus) by cDNA-AFLPS
[作者:Taboada, X; Robledo, D; Del Palacio, L; Rodeiro, A; Felip, A; Martinez, P; Vinas, A,期刊:Gene, 页码:250-261 , 文章类型: Article,,卷期:2012年492-1]
- Turbot is one of the most important farmed fish in Europe. This species exhibits a considerable sexual dimorphism in growth and sexual maturity that makes the all-female production recommended for turbot farming. Our kno...
- Up-regulation of osteopontin expression by aryl hydrocarbon receptor via both ligand-dependent and ligand-independent pathways in lung cancer
[作者:Chuang, CY; Chang, H; Lin, PP; Sun, SJ; Chen, PH; Lin, YY; Sheu, GT; Ko, JL; Hsu, SL; Chang, JHT,期刊:Gene, 页码:262-269 , 文章类型: Article,,卷期:2012年492-1]
- The secreted glycol-phosphoprotein OPN not only plays important roles in immune responses and tissue remodeling but is also intimately involved in tumorigenesis. It is up-regulated in various cancers and correlated with ...
- Identification and characterization of splicing variants of PLEKHA5 (Plekha5) during brain development
[作者:Yamada, K; Nomura, N; Yamano, A; Yamada, Y; Wakamatsu, N,期刊:Gene, 页码:270-275 , 文章类型: Article,,卷期:2012年492-1]
- PLEKHA5 (pleckstrin homology domain-containing protein family A, member 5) belongs to the PLEKHA family (PLEKHA1-6); however, the properties of this protein remain poorly characterized. We have identified and characteriz...
- A comprehensive analysis of fifteen genes of steviol glycosides biosynthesis pathway in Stevia rebaudiana (Bertoni)
[作者:Kumar, H; Kaul, K; Bajpai-Gupta, S; Kaul, VK; Kumar, S,期刊:Gene, 页码:276-284 , 文章类型: Article,,卷期:2012年492-1]
- Stevia [Stevia rebuaidana (Bertoni): family: Asteraceae] is known to yield diterpenoid steviol glycosides (SGs), which are about 300 times sweeter than sugar. The present work analyzed the expression of various genes of ...
- Molecular mining of GGAA tagged transcripts and their expression in water buffalo Bubalus bubalis
[作者:Rawal, L; Ali, S; Ali, S,期刊:Gene, 页码:290-295 , 文章类型: Article,,卷期:2012年492-1]
- Repeat sequences are involved in regulation of gene expression both at the transcriptional and translational level. In the mammalian genomes, tri- and tetranucleotide repeats like ATA, AATA, GGAA and GAAA have been assoc...
- Molecular cloning and functional characterization of the porcine extracellular domain of Receptor Activator of NF-kappa B Ligand (sRANKL)
[作者:Bocker, W; Radic, T; Schonitzer, V; Haasters, F; Mutschler, W; Schieker, M,期刊:Gene, 页码:296-304 , 文章类型: Article,,卷期:2012年492-1]
- Receptor Activator of NF-kappa B Ligand (RANKL) plays a pivotal role as a regulator of osteoclast activity and is involved in osteoporosis. Here, we report the cloning and functional characterization of the complete extr...
- Nucleofection-based gene targeting in human pre-B cells
[作者:Kurosawa, A; Saito, S; Mori, M; Adachi, N,期刊:Gene, 页码:305-308 , 文章类型: Article,,卷期:2012年492-1]
- Electroporation is a powerful and convenient means for transfection of nonviral vectors into mammalian cells, providing an essential tool for numerous applications including gene targeting via homologous recombination. R...
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