- The proteomics of plant cell membranes
[作者:Komatsu, S; Konishi, H; Hashimoto, M,期刊:Cancer research, 页码:103-112 , 文章类型: Article,,卷期:2012年72-3]
- Membrane proteins are involved in many different functions depending on their location in the cell. Characterization of the membrane proteome can bring new insights to the function of different plant membrane systems and...
- Immunotherapy with PI3K Inhibitor and Toll- Like Receptor Agonist Induces IFN-gamma+IL-17(+) Polyfunctional T Cells That Mediate Rejection of Murine Tumors
[作者:Marshall, NA; Galvin, KC; Corcoran, AMB; Boon, L; Higgs, R; Mills, KHG,期刊:Cancer research, 页码:581-591 , 文章类型: Article,,卷期:2012年72-3]
- The immunosuppressive microenvironment in tumors hampers the induction of antitumor immunity by vaccines or immunotherapies. Toll-like receptor (TLR) ligands have the potential to treat tumors, but they can exert a mixtu...
- IFN beta Produced by TLR4-Activated Tumor Cells Is Involved in Improving the Antitumoral Immune Response
[作者:Nunez, NG; Andreani, V; Crespo, MI; Nocera, DA; Breser, ML; Moron, G; Dejager, L; Libert, C; Rivero, V; Maccioni, M,期刊:Cancer research, 页码:592-603 , 文章类型: Article,,卷期:2012年72-3]
- Toll-like receptor (TLR) ligands may be a valuable tool to promote antitumor responses by reinforcing antitumor immunity. In addition to their expression in immune cells, functional TLRs are also expressed by many cancer...
- S100A7 Enhances Mammary Tumorigenesis through Upregulation of Inflammatory Pathways
[作者:Nasser, MW; Qamri, Z; Deol, YS; Ravi, J; Powell, CA; Trikha, P; Schwendener, RA; Bai, XF; Shilo, K; Zou, XH; Leone, G; Wolf, R; Yuspa, SH; Ganju, RK,期刊:Cancer research, 页码:604-615 , 文章类型: Article,,卷期:2012年72-3]
- S100A7/psoriasin, a member of the epidermal differentiation complex, is widely overexpressed in invasive estrogen receptor (ER)alpha-negative breast cancers. However, it has not been established whether S100A7 contribute...
- Common Structural and Epigenetic Changes in the Genome of Castration-Resistant Prostate Cancer
[作者:Friedlander, TW; Roy, R; Tomlins, SA; Ngo, VT; Kobayashi, Y; Azameera, A; Rubin, MA; Pienta, KJ; Chinnaiyan, A; Ittmann, MM; Ryan, CJ; Paris, PL,期刊:Cancer research, 页码:616-625 , 文章类型: Article,,卷期:2012年72-3]
- Progression of primary prostate cancer to castration-resistant prostate cancer (CRPC) is associated with numerous genetic and epigenetic alterations that are thought to promote survival at metastatic sites. In this study...
- Sef Downregulation by Ras Causes MEK1/2 to Become Aberrantly Nuclear Localized Leading to Polyploidy and Neoplastic Transformation
[作者:Duhamel, S; Hebert, J; Gaboury, L; Bouchard, A; Simon, R; Sauter, G; Basik, M; Meloche, S,期刊:Cancer research, 页码:626-635 , 文章类型: Article,,卷期:2012年72-3]
- Subcellular trafficking of key oncogenic signal pathway components is likely to be crucial for neoplastic transformation, but little is known about how such trafficking processes are spatially controlled. In this study, ...
- Monoallelic Expression Determines Oncogenic Progression and Outcome in Benign and Malignant Brain Tumors
[作者:Walker, EJ; Zhang, C; Castelo-Branco, P; Hawkins, C; Wilson, W; Zhukova, N; Alon, N; Novokmet, A; Baskin, B; Ray, P; Knobbe, C; Dirks, P; Taylor, MD; Croul, S; Malkin, D; Tabori, U,期刊:Cancer research, 页码:636-644 , 文章类型: Article,,卷期:2012年72-3]
- Although monoallelic expression (MAE) is a frequent genomic event in normal tissues, its role in tumorigenesis remains unclear. Here we carried out single-nucleotide polymorphism arrays on DNA and RNA from a large cohort...
- Classifying Human Brain Tumors by Lipid Imaging with Mass Spectrometry
[作者:Eberlin, LS; Norton, I; Dill, AL; Golby, AJ; Ligon, KL; Santagata, S; Cooks, RG; Agar, NYR,期刊:Cancer research, 页码:645-654 , 文章类型: Article,,卷期:2012年72-3]
- Brain tissue biopsies are required to histologically diagnose brain tumors, but current approaches are limited by tissue characterization at the time of surgery. Emerging technologies such as mass spectrometry imaging ca...
- A Novel FoxM1-Caveolin Signaling Pathway Promotes Pancreatic Cancer Invasion and Metastasis
[作者:Huang, C; Qiu, ZJ; Wang, LW; Peng, ZH; Jia, ZL; Logsdon, CD; Le, XD; Wei, DY; Huang, SY; Xie, KP,期刊:Cancer research, 页码:655-665 , 文章类型: Article,,卷期:2012年72-3]
- Caveolin-1 (Cav-1), a principal structural component of caveolar membrane domains, contributes to cancer development but its precise functional roles and regulation remain unclear. In this study, we determined the oncoge...
- Nucleotide Excision Repair Factor XPC Enhances DNA Damage-Induced Apoptosis by Downregulating the Antiapoptotic Short Isoform of Caspase-2
[作者:Wang, QE; Han, CH; Zhang, B; Sabapathy, K; Wani, AA,期刊:Cancer research, 页码:666-675 , 文章类型: Article,,卷期:2012年72-3]
- XPC protein is a critical DNA damage recognition factor in nucleotide excision repair for which genetic deficiency confers a predisposition to cancer. In this study, we show that XPC has a function that is independent of...
- Prevalent Serum Antibody Is Not a Marker of Immune Protection against Acquisition of Oncogenic HPV16 in Men
[作者:Lu, BB; Viscidi, RP; Wu, YG; Lee, JH; Nyitray, AG; Villa, LL; Lazcano-Ponce, E; da Silva, RJC; Baggio, ML; Quiterio, M; Salmeron, J; Smith, DC; Abrahamsen, ME; Papenfuss, MR; Stockwell, HG; Giuliano, AR,期刊:Cancer research, 页码:676-685 , 文章类型: Article,,卷期:2012年72-3]
- In women, naturally induced anti-human papilloma virus (HPV) serum antibodies are a likely marker of host immune protection against subsequent HPV acquisition and progression to precancerous lesions and cancers. However,...
- Mitochondrial DNA Sequence Variation and Risk of Pancreatic Cancer
[作者:Lam, ET; Bracci, PM; Holly, EA; Chu, C; Poon, A; Wan, E; White, K; Kwok, PY; Pawlikowska, L; Tranah, GJ,期刊:Cancer research, 页码:686-695 , 文章类型: Article,,卷期:2012年72-3]
- Although the mitochondrial genome exhibits high mutation rates, common mitochondrial DNA (mtDNA) variation has not been consistently associated with pancreatic cancer. Here, we comprehensively examined mitochondrial geno...
- Urinary Estrogens and Estrogen Metabolites and Subsequent Risk of Breast Cancer among Premenopausal Women
[作者:Eliassen, AH; Spiegelman, D; Xu, X; Keefer, LK; Veenstra, TD; Barbieri, RL; Willett, WC; Hankinson, SE; Ziegler, RG,期刊:Cancer research, 页码:696-706 , 文章类型: Article,,卷期:2012年72-3]
- Endogenous estrogens and estrogen metabolism are hypothesized to be associated with premenopausal breast cancer risk but evidence is limited. We examined 15 urinary estrogens/estrogen metabolites and breast cancer risk a...
- Genetic Determinants for Promoter Hypermethylation in the Lungs of Smokers: A Candidate Gene-Based Study
[作者:Leng, SG; Stidley, CA; Liu, YS; Edlund, CK; Willink, RP; Han, YH; Landi, MT; Thun, M; Picchi, MA; Bruse, SE; Crowell, RE; Van den Berg, D; Caporaso, NE; Amos, CI; Siegfried, JM; Tesfaigzi, Y; Gilliland, FD; Belinsky, SA,期刊:Cancer research, 页码:707-715 , 文章类型: Article,,卷期:2012年72-3]
- The detection of tumor suppressor gene promoter methylation in sputum-derived exfoliated cells predicts early lung cancer. Here, we identified genetic determinants for this epigenetic process and examined their biologic ...
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