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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共25条记录   Bovine Pancreatic Ribonuclease: Fifty Years of the First Enzymatic Reaction Mechanism [作者：Cuchillo, CM; Nogues, MV; Raines, RT,期刊：Biochemistry, 页码：7835-7841 , 文章类型： Article，,卷期：2011年50-37] Fifty years ago, the group of Tony Mathias and Bob Rabin at University College London deduced the first mechanism for catalysis by an enzyme, ribonuclease [Findlay, D., Herries, D. G., Mathias, A. P., Rabin, B. R., and R... When Galectins Recognize Glycans: From Biochemistry to Physiology and Back Again [作者：Di Lella, S; Sundblad, V; Cerliani, JP; Guardia, CM; Estrin, DA; Vasta, GR; Rabinovich, GA,期刊：Biochemistry, 页码：7842-7857 , 文章类型： Article，,卷期：2011年50-37] In the past decade, increasing efforts have been devoted to the study of galectins, a family of evolutionarily conserved glycan-binding proteins with multifunctional properties. Galectins function, either intracellularly... Identification of Proline Residues in or near the Transmembrane Helices of the Human Breast Cancer Resistance Protein (BCRP/ABCG2) That Are Important for Transport Activity and Substrate Specificity [作者：Ni, ZL; Bikadi, Z; Shuster, DL; Zhao, CS; Rosenberg, MF; Mao, QC,期刊：Biochemistry, 页码：8057-8066 , 文章类型： Article，,卷期：2011年50-37] The human breast cancer resistance protein (BCRP/ABCG2) confers multidrug resistance and mediates the active efflux of drugs and xenobiotics. BCRP contains one nucleotide-binding domain (NBD) followed by one membrane-spa... The Glutamine Side Chain at Position 91 on the beta 5a-beta 5b Loop of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Is Required for Stabilizing the dNTP Binding Pocket [作者：Pandey, N; Mishra, CA; Manvar, D; Upadhyay, AK; Talele, TT; Comollo, TW; Kaushik-Basu, N; Pandey, VN,期刊：Biochemistry, 页码：8067-8077 , 文章类型： Article，,卷期：2011年50-37] Earlier, we postulated that Gln91 of human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) stabilizes the side chain of Tyr183 via hydrogen bonding interaction between 0(H) of Tyr183 and CO of Q91 [Harris,... Crystal Structure and Function of Human Nucleoplasmin (Npm2): A Histone Chaperone in Oocytes and Embryos [作者：Platonova, O; Akey, IV; Head, JF; Akey, CW,期刊：Biochemistry, 页码：8078-8089 , 文章类型： Article，,卷期：2011年50-37] Human Npm2 is an ortholog of Xenopus nucleoplasmin (Np), a chaperone that binds histones. We have determined the crystal structure of a truncated Npm2-core at 1.9 angstrom resolution and show that the N-terminal domains ... A Blue Corrinoid from Partial Degradation of Vitamin B(12) in Aqueous Bicarbonate: Spectra, Structure, and Interaction with Proteins of B(12) Transport [作者：Fedosov, SN; Ruetz, M; Gruber, K; Fedosova, NU; Krautler, B,期刊：Biochemistry, 页码：8090-8101 , 文章类型： Article，,卷期：2011年50-37] Cobalarnin (Cbl) is a complex cofactor produced only by bacteria but used by all animals and humans. Cyanocobalamin (vitamin B(12), CNCb1) is one commonly isolated form of cobalamin. B12 belongs to a large group of corri... Tolerance to Changes in Membrane Lipid Composition as a Selected Trait of Membrane Proteins [作者：Sanders, CR; Mittendorf, KF,期刊：Biochemistry, 页码：7858-7867 , 文章类型： Article，,卷期：2011年50-37] Membrane lipid composition can vary dramatically across the three domains of life and even within single organisms. Here we review evidence that the lipid-exposed surfaces of membrane proteins have generally evolved to m... Self-Assembly of Escherichia coli MutL and Its Complexes with DNA [作者：Niedziela-Majka, A; Maluf, NK; Antony, E; Lohman, TM,期刊：Biochemistry, 页码：7868-7880 , 文章类型： Article，,卷期：2011年50-37] The Escherichia coil MutL protein regulates the activity of several enzymes, including MutS, MutH, and UvrD, during methyl-directed mismatch repair of DNA. We have investigated the self-association properties of MutL and... Allosteric Interactions of DNA and Nucleotides with S. cerevisiae RSC [作者：Malik, SS; Rich, E; Viswanathan, R; Cairns, BR; Fischer, CJ,期刊：Biochemistry, 页码：7881-7890 , 文章类型： Article，,卷期：2011年50-37] RSC (remodel the structure of chromatin) is an essential chromatin remodeler of Saccharomyces cerevisiae that has been shown to have DNA translocase properties. We studied the DNA binding properties of a "trimeric minima... Design and Characterization of Stabilized Derivatives of Human CD4D12 and CD4D1 [作者：Saha, P; Barua, B; Bhattacharyya, S; Balamurali, MM; Schief, WR; Baker, D; Varadarajan, R,期刊：Biochemistry, 页码：7891-7900 , 文章类型： Article，,卷期：2011年50-37] CD4 is present on the surface of T-lymphocytes and is the primary cellular receptor for HIV-1. CD4 consists of a cytoplasmic tail, one transmembrane region, and four extracellular domains, D1-D4. A construct consisting o... Dynamics of Nucleosomes Assessed with Time-Lapse High-Speed Atomic Force Microscopy [作者：Miyagi, A; Ando, T; Lyubchenko, YL,期刊：Biochemistry, 页码：7901-7908 , 文章类型： Article，,卷期：2011年50-37] A fundamental challenge of gene regulation is the accessibility of DNA within nucleosomes. Recent studies performed by various techniques, including single-molecule approaches, led to the realization that nucleosomes are... Proline in Transmembrane Domain of Type II Protein DPP-IV Governs Its Translocation Behavior through Endoplasmic Reticulum [作者：Chung, KM; Huang, CH; Cheng, JH; Tsai, CH; Suen, CS; Hwang, MJ; Chen, X,期刊：Biochemistry, 页码：7909-7918 , 文章类型： Article，,卷期：2011年50-37] A transmembrane domain (TMD) at the N-terminus of a membrane protein is a signal sequence that targets the protein to the endoplasmic reticulum (ER) membrane. Pro line is found more frequently in TM helices compared to w... What Determines the Activity of Antimicrobial and Cytolytic Peptides in Model Membranes [作者：Clark, KS; Svetlovics, J; McKeown, AN; Huskins, L; Almeida, PF,期刊：Biochemistry, 页码：7919-7932 , 文章类型： Article，,卷期：2011年50-37] We previously proposed three hypotheses relating the mechanism of antimicrobial and cytolytic peptides in model membranes to the Gibbs free energies of binding and insertion into the membrane [Almeida, P. F., and Pokorny... Relationship between Conformational Stability and Amplification Efficiency of Prions [作者：Gonzalez-Montalban, N; Makarava, N; Savtchenko, R; Baskakov, IV,期刊：Biochemistry, 页码：7933-7940 , 文章类型： Article，,卷期：2011年50-37] Recent studies demonstrated that the efficiency, rate, and yield of prion amplification in vitro could be substantially improved by supplementing protein misfolding cyclic amplification (PMCA) with Teflon beads [Gonzalez... Mycobacterium tuberculosis NmtR Harbors a Nickel Sensing Site with Parallels to Escherichia coli RcnR [作者：Reyes-Caballero, H; Lee, CW; Giedroc, DP,期刊：Biochemistry, 页码：7941-7952 , 文章类型： Article，,卷期：2011年50-37] Mycobacterium tuberculosis NmtR is a Ni(II)/Co(II)-sensing metalloregulatory protein from the extensively studied ArsR/SmtB family. Two Ni(II) ions bind to the NmtR dimer to form octahedral coordination complexes with th... Reduction of the [2Fe-2S] Cluster Accompanies Formation of the Intermediate 9-Mercaptodethiobiotin in Escherichia coli Biotin Synthase [作者：Taylor, AM; Stoll, S; Britt, RD; Jarrett, JT,期刊：Biochemistry, 页码：7953-7963 , 文章类型： Article，,卷期：2011年50-37] Biotin synthase catalyzes the conversion of dethiobiotin (DTB) to biotin through the oxidative addition of sulfur between two saturated carbon atoms, generating a thiophane ring fused to the existing ureido ring. Biotin ...