- Significance of Remyelination by Neural Stem/Progenitor Cells Transplanted into the Injured Spinal Cord
[作者:Yasuda, A; Tsuji, O; Shibata, S; Nori, S; Takano, M; Kobayashi, Y; Takahashi, Y; Fujiyoshi, K; Hara, CM; Miyawaki, A; Okano, HJ; Toyama, Y; Nakamura, M; Okano, H,期刊:Stem Cells, 页码:1983-1994 , 文章类型: Article,,卷期:2011年29-12]
- Previous reports of functional recovery from spinal cord injury (SCI) in rodents and monkeys after the delayed transplantation of neural stem/progenitor cells (NS/PCs) have raised hopes that stem cell therapy could be us...
- Changes in Glycosphingolipid Composition During Differentiation of Human Embryonic Stem Cells to Ectodermal or Endodermal Lineages
[作者:Liang, YJ; Yang, BC; Chen, JM; Lin, YH; Huang, CL; Cheng, YY; Hsu, CY; Khoo, KH; Shen, CN; Yu, J,期刊:Stem Cells, 页码:1995-2004 , 文章类型: Article,,卷期:2011年29-12]
- Glycosphingolipids (GSLs) are ubiquitous components of cell membranes that can act as mediators of cell adhesion and signal transduction and can possibly be used as cell type-specific markers. Our previous study indicate...
- Increased Re-Entry into Cell Cycle Mitigates Age-Related Neurogenic Decline in the Murine Subventricular Zone
[作者:Stoll, EA; Habibi, BA; Mikheev, AM; Lasiene, J; Massey, SC; Swanson, KR; Rostomily, RC; Horner, PJ,期刊:Stem Cells, 页码:2005-2017 , 文章类型: Article,,卷期:2011年29-12]
- Although new neurons are produced in the subventricular zone (SVZ) of the adult mammalian brain, fewer functional neurons are produced with increasing age. The age-related decline in neurogenesis has been attributed to a...
- Nonintegrating Knockdown and Customized Scaffold Design Enhances Human Adipose-Derived Stem Cells in Skeletal Repair
[作者:Levi, B; Hyun, JS; Nelson, ER; Li, SL; Montoro, DT; Wan, DC; Jia, FJ; Glotzbach, JC; James, AW; Lee, M; Huang, M; Quarto, N; Gurtner, GC; Wu, JC; Longaker, MT,期刊:Stem Cells, 页码:2018-2029 , 文章类型: Article,,卷期:2011年29-12]
- An urgent need exists in clinical medicine for suitable alternatives to available techniques for bone tissue repair. Human adipose-derived stem cells (hASCs) represent a readily available, autogenous cell source with wel...
- CD34 Promotes Satellite Cell Motility and Entry into Proliferation to Facilitate Efficient Skeletal Muscle Regeneration
[作者:Alfaro, LAS; Dick, SA; Siegel, AL; Anonuevo, AS; McNagny, KM; Megeney, LA; Cornelison, DDW; Rossi, FMV,期刊:Stem Cells, 页码:2030-2041 , 文章类型: Article,,卷期:2011年29-12]
- Expression of the cell surface sialomucin CD34 is common to many adult stem cell types, including muscle satellite cells. However, no clear stem cell or regeneration-related phenotype has ever been reported in mice lacki...
- Myb Controls Intestinal Stem Cell Genes and Self-Renewal
[作者:Cheasley, D; Pereira, L; Lightowler, S; Vincan, E; Malaterre, J; Ramsay, RG,期刊:Stem Cells, 页码:2042-2050 , 文章类型: Article,,卷期:2011年29-12]
- Rapid advances have been made in the understanding of how the highly proliferative gastrointestinal tract epithelium is regulated under homeostasis and disease. The identification of putative intestinal stem cell (ISC) g...
- Human Cardiac Progenitor Cell Grafts as Unrestricted Source of Supernumerary Cardiac Cells in Healthy Murine Hearts
[作者:Forte, G; Pietronave, S; Nardone, G; Zamperone, A; Magnani, E; Pagliari, S; Pagliari, F; Giacinti, C; Nicoletti, C; Musaro, A; Rinaldi, M; Ribezzo, M; Comoglio, C; Traversa, E; Okano, T; Minieri, M; Prat, M; Di Nardo, P,期刊:Stem Cells, 页码:2051-2061 , 文章类型: Article,,卷期:2011年29-12]
- Human heart harbors a population of resident progenitor cells that can be isolated by stem cell antigen-1 antibody and expanded in culture. These cells can differentiate into cardiomyocytes in vitro and contribute to car...
- Nestin- and Doublecortin-Positive Cells Reside in Adult Spinal Cord Meninges and Participate in Injury-Induced Parenchymal Reaction
[作者:Decimo, I; Bifari, F; Rodriguez, FJ; Malpeli, G; Dolci, S; Lavarini, V; Pretto, S; Vasquez, S; Sciancalepore, M; Montalbano, A; Berton, V; Krampera, M; Fumagalli, G,期刊:Stem Cells, 页码:2062-2076 , 文章类型: Article,,卷期:2011年29-12]
- Adult spinal cord has little regenerative potential, thus limiting patient recovery following injury. In this study, we describe a new population of cells resident in the adult rat spinal cord meninges that express the n...
- Dedifferentiation-Reprogrammed Mesenchymal Stem Cells with Improved Therapeutic Potential
[作者:Liu, Y; Jiang, XH; Zhang, XH; Chen, R; Sun, TT; Fok, KL; Dong, JD; Tsang, LL; Yi, SQ; Ruan, YC; Guo, JH; Yu, MK; Tian, YM; Chung, YW; Yang, M; Xu, WM; Chung, CM; Li, TY; Chan, HC,期刊:Stem Cells, 页码:2077-2089 , 文章类型: Article,,卷期:2011年29-12]
- Stem cell transplantation has been shown to improve functional outcome in degenerative and ischemic disorders. However, low in vivo survival and differentiation potential of the transplanted cells limits their overall ef...
- Brief Report: Phenotypic Rescue of Induced Pluripotent Stem Cell-Derived Motoneurons of a Spinal Muscular Atrophy Patient
[作者:Chang, T; Zheng, WY; Tsark, W; Bates, S; Huang, H; Lin, RJ; Yee, JK,期刊:Stem Cells, 页码:2090-2093 , 文章类型: Article,,卷期:2011年29-12]
- Spinal muscular atrophy (SMA) is one of the most common autosomal recessive disorders in humans and is a common genetic cause of infant mortality. The disease is caused by loss of the survival of motoneuron (SMN) protein...
- Brief Report: L1 Cell Adhesion Molecule, a Novel Surface Molecule of Human Embryonic Stem Cells, is Essential for Self-Renewal and Pluripotency
[作者:Son, YS; Seong, RH; Ryu, CJ; Cho, YS; Bae, KH; Chung, SJ; Lee, B; Min, JK; Hong, HJ,期刊:Stem Cells, 页码:2094-2099 , 文章类型: Article,,卷期:2011年29-12]
- Despite the recent identification of surface markers of undifferentiated human embryonic stem cells (hESCs), the crucial cell-surface molecules that regulate the self-renewal capacity of hESCs remain largely undefined. H...
- Concise Review: Alchemy of Biology: Generating Desired Cell Types from Abundant and Accessible Cells
[作者:Pournasr, B; Khaloughi, K; Salekdeh, GH; Totonchi, M; Shahbazi, E; Baharvand, H,期刊:Stem Cells, 页码:1933-1941 , 文章类型: Review,,卷期:2011年29-12]
- A major goal of regenerative medicine is to produce cells to participate in the generation, maintenance, and repair of tissues that are damaged by disease, aging, or trauma, such that function is restored. The establishm...
- MEK-ERK Signaling Dictates DNA-Repair Gene MGMT Expression and Temozolomide Resistance of Stem-Like Glioblastoma Cells via the MDM2-p53 Axis
[作者:Sato, A; Sunayama, J; Matsuda, K; Seino, S; Suzuki, K; Watanabe, E; Tachibana, K; Tomiyama, A; Kayama, T; Kitanaka, C,期刊:Stem Cells, 页码:1942-1951 , 文章类型: Article,,卷期:2011年29-12]
- Overcoming the resistance of glioblastoma cells against temozolomide, the first-line chemotherapeutic agent of choice for newly diagnosed glioblastoma, is a major therapeutic challenge in the management of this deadly br...
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