- Aldehyde Dehydrogenase Activity of Breast Cancer Stem Cells is Primarily Due to Isoform ALDH1A3 and Its Expression is Predictive of Metastasis
[作者：Marcato, P; Dean, CA; Pan, D; Araslanova, R; Gillis, M; Joshi, M; Helyer, L; Pan, L; Leidal, A; Gujar, S; Giacomantonio, CA; Lee, PWK,期刊：Stem Cells, 页码：32-45 , 文章类型： Article，,卷期：2011年29-1]
- Cancer stem cells (CSCs) are proposed to initiate cancer and propagate metastasis. Breast CSCs identified by aldehyde dehydrogenase (ALDH) activity are highly tumorigenic in xenograft models. However, in patient breast t...
- Human Embryonic Stem Cells Suffer from Centrosomal Amplification
[作者：Holubcova, Z; Matula, P; Sedlackova, M; Vinarsky, V; Dolezalova, D; Barta, T; Dvorak, P; Hampl, A,期刊：Stem Cells, 页码：46-56 , 文章类型： Article，,卷期：2011年29-1]
- Propagation of human embryonic stem cells (hESCs) in culture tends to alter karyotype, potentially limiting the prospective use of these cells in patients. The chromosomal instability of some malignancies is considered t...
- From Hair to Cornea: Toward the Therapeutic Use of Hair Follicle-Derived Stem Cells in the Treatment of Limbal Stem Cell Deficiency
[作者：Meyer-Blazejewska, EA; Call, MK; Yamanaka, O; Liu, HS; Schlotzer-Schrehardt, U; Kruse, FE; Kao, WW,期刊：Stem Cells, 页码：57-66 , 文章类型： Article，,卷期：2011年29-1]
- Limbal stem cell deficiency (LSCD) leads to severe ocular surface abnormalities that can result in the loss of vision. The most successful therapy currently being used is transplantation of limbal epithelial cell sheets ...
- Mesenchymal Lineage Stem Cells Have Pronounced Anti-Inflammatory Effects in the Twitcher Mouse Model of Krabbe's Disease
[作者：Ripoll, CB; Flaat, M; Klopf-Eiermann, J; Fisher-Perkins, JM; Trygg, CB; Scruggs, BA; McCants, ML; Leonard, HP; Lin, AF; Zhang, SJ; Eagle, ME; Alvarez, X; Li, YT; Li, SC; Gimble, JM; Bunnell, BA,期刊：Stem Cells, 页码：67-77 , 文章类型： Article，,卷期：2011年29-1]
- The twitcher mouse is an animal model of Krabbe's disease (KD), which is a neurodegenerative lysosomal storage disorder resulting from the absence of functional lysosomal enzyme galactocerebrosidase (GALC). This disease ...
- Tracking Stem Cell Differentiation in the Setting of Automated Optogenetic Stimulation
[作者：Stroh, A; Tsai, HC; Wang, LP; Zhang, F; Kressel, J; Aravanis, A; Santhanam, N; Deisseroth, K; Konnerth, A; Schneider, MB,期刊：Stem Cells, 页码：78-88 , 文章类型： Article，,卷期：2011年29-1]
- Membrane depolarization has been shown to play an important role in the neural differentiation of stem cells and in the survival and function of mature neurons. Here, we introduce a microbial opsin into ESCs and develop ...
- Sox1 Maintains the Undifferentiated State of Cortical Neural Progenitor Cells via the Suppression of Prox1-Mediated Cell Cycle Exit and Neurogenesis
[作者：Elkouris, M; Balaskas, N; Poulou, M; Politis, PK; Panayiotou, E; Malas, S; Thomaidou, D; Remboutsika, E,期刊：Stem Cells, 页码：89-98 , 文章类型： Article，,卷期：2011年29-1]
- Neural stem/progenitor cells maintain their identity via continuous self-renewal and suppression of differentiation. Gain-of-function experiments in the chick revealed an involvement for Sox1-3 transcription factors in t...
- Mesenchymal Stromal Cells Expressing Heme Oxygenase-1 Reverse Pulmonary Hypertension
[作者：Liang, OD; Mitsialis, SA; Chang, MS; Vergadi, E; Lee, C; Aslam, M; Fernandez-Gonzalez, A; Liu, XL; Baveja, R; Kourembanas, S,期刊：Stem Cells, 页码：99-107 , 文章类型： Article，,卷期：2011年29-1]
- Pulmonary arterial hypertension (PAH) remains a serious disease, and although current treatments may prolong and improve quality of life, search for novel and effective therapies is warranted. Using genetically modified ...
- GSK-3 Beta Inhibition Promotes Engraftment of Ex Vivo-Expanded Hematopoietic Stem Cells and Modulates Gene Expression
[作者：Ko, KH; Holmes, T; Palladinetti, P; Song, E; Nordon, R; O'Brien, TA; Dolnikov, A,期刊：Stem Cells, 页码：108-118 , 文章类型： Article，,卷期：2011年29-1]
- Glycogen synthase kinase-3 beta (GSK-3 beta) has been identified as an important regulator of stem cell function acting through activation of the wingless (Wnt) pathway. Here, we report that treatment with an inhibitor o...
- Repression of Mammary Stem/Progenitor Cells by p53 Is Mediated by Notch and Separable from Apoptotic Activity
[作者：Tao, LW; Roberts, AL; Dunphy, KA; Bigelow, C; Yan, HH; Jerry, DJ,期刊：Stem Cells, 页码：119-127 , 文章类型： Article，,卷期：2011年29-1]
- Breast cancer is the most common tumor among women with inherited mutations in the p53 gene (Li-Fraumeni syndrome). The tumors represent the basal-like subtype, which has been suggested to originate from mammary stem/pro...
- Distinct Roles for Wnt-4 and Wnt-11 During Retinoic Acid-Induced Neuronal Differentiation
[作者：Elizalde, C; Campa, VM; Caro, M; Schlangen, K; Aransay, AM; dM Vivanco, M; Kypta, RM,期刊：Stem Cells, 页码：141-153 , 文章类型： Article，,卷期：2011年29-1]
- Retinoic acid and Wnt/beta-catenin signals play important roles during neuronal differentiation but less is known about noncanonical Wnt signals in this context. We examined retinoic acid and Wnt signaling in two human e...
- Epithelial-Connective Tissue Interactions Induced by Thyroid Hormone Receptor Are Essential for Adult Stem Cell Development in the Xenopus laevis Intestine
[作者：Hasebe, T; Buchholz, DR; Shi, YB; Ishizuya-Oka, A,期刊：Stem Cells, 页码：154-161 , 文章类型： Article，,卷期：2011年29-1]
- In the amphibian intestine during metamorphosis, stem cells appear and generate the adult absorptive epithelium, analogous to the mammalian one, under the control of thyroid hormone (TH). We have previously shown that th...
- Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Conversation with Cinzia Rota
[作者：Lako, M; Trounson, AO; Daher, S,期刊：Stem Cells, 页码：1-2 , 文章类型： Editorial Material，,卷期：2011年29-1]
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- Concise Review: Mesenchymal Stem Cell Treatment of the Complications of Diabetes Mellitus
[作者：Volarevic, V; Arsenijevic, N; Lukic, ML; Stojkovic, M,期刊：Stem Cells, 页码：5-10 , 文章类型： Review，,卷期：2011年29-1]
- Mesenchymal stem cells (MSCs) are multipotent, self-renewing cells that can be found in almost all postnatal organs and tissues. The main functional characteristics of MSCs are their immunomodulatory ability, capacity fo...
- Concise Review: Dissecting a Discrepancy in the Literature: Do Mesenchymal Stem Cells Support or Suppress Tumor Growth?
[作者：Klopp, AH; Gupta, A; Spaeth, E; Andreeff, M; Marini, F,期刊：Stem Cells, 页码：11-19 , 文章类型： Review，,卷期：2011年29-1]
- The discovery that mesenchymal stem cells (MSCs) are recruited into tumors has led to a great deal of interest over the past decade in the function of MSCs in tumors. To address this, investigators have used a variety of...
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