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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共18条记录   Ets2 Regulates Colonic Stem Cells and Sensitivity to Tumorigenesis [作者：Munera, J; Cecena, G; Jedlicka, P; Wankell, M; Oshima, RG,期刊：Stem Cells, 页码：430-439 , 文章类型： Article，,卷期：2011年29-3] Ets2 has both tumor repressive and supportive functions for different types of cancer. We have investigated the role of Ets2 within intestinal epithelial cells in postnatal mouse colon development and tumorigenesis. Cond... Alternative Lengthening of Telomeres in Human Glioma Stem Cells [作者：Silvestre, DC; Pineda, JR; Hoffschir, F; Studler, JM; Mouthon, MA; Pflumio, F; Junier, MP; Chneiweiss, H; Boussin, FD,期刊：Stem Cells, 页码：440-451 , 文章类型： Article，,卷期：2011年29-3] Cancer stem cells are increasingly recognized as major therapeutic targets. We report here the isolation of glioma stem cells (GSCs) maintaining telomere length through a telomerase-independent mechanism known as alterna... Side Population is Not Necessary or Sufficient for a Cancer Stem Cell Phenotype in Glioblastoma Multiforme [作者：Broadley, KWR; Hunn, MK; Farrand, KJ; Price, KM; Grasso, C; Miller, RJ; Hermans, IF; McConnell, MJ,期刊：Stem Cells, 页码：452-461 , 文章类型： Article，,卷期：2011年29-3] There is strong evidence for the existence of cancer stem cells (CSCs) in the aggressive brain tumor glioblastoma multiforme (GBM). These cells have stem-like self-renewal activity and increased tumor initiation capacity... A Targeted NKX2.1 Human Embryonic Stem Cell Reporter Line Enables Identification of Human Basal Forebrain Derivatives [作者：Goulburn, AL; Alden, D; Davis, RP; Micallef, SJ; Ng, ES; Yu, QC; Lim, SM; Soh, CL; Elliott, DA; Hatzistavrou, T; Bourke, J; Watmuff, B; Lang, RJ; Haynes, JM; Pouton, CW; Giudice, A; Trounson, AO; Anderson, SA; Stanley, EG; Elefanty, AG,期刊：Stem Cells, 页码：462-473 , 文章类型： Article，,卷期：2011年29-3] We have used homologous recombination in human embryonic stem cells (hESCs) to insert sequences encoding green fluorescent protein (GFP) into the NKX2.1 locus, a gene required for normal development of the basal forebrai... Pramel7 Mediates LIF/STAT3-Dependent Self-Renewal in Embryonic Stem Cells [作者：Casanova, EA; Shakhova, O; Patel, SS; Asner, IN; Pelczar, P; Weber, FA; Graf, U; Sommer, L; Burki, K; Cinelli, P,期刊：Stem Cells, 页码：474-485 , 文章类型： Article，,卷期：2011年29-3] A unique and complex signaling network allows ESCs to undergo extended proliferation in vitro, while maintaining their capacity for multilineage differentiation. Genuine ESC identity can only be maintained when both self... Mitochondrial Function Controls Proliferation and Early Differentiation Potential of Embryonic Stem Cells [作者：Mandal, S; Lindgren, AG; Srivastava, AS; Clark, AT; Banerjee, U,期刊：Stem Cells, 页码：486-495 , 文章类型： Article，,卷期：2011年29-3] Pluripotent stem cells hold significant promise in regenerative medicine due to their unlimited capacity for self-renewal and potential to differentiate into any cell type of the body. In this study, we demonstrate that ... Genome-Wide Studies Reveal That Lin28 Enhances the Translation of Genes Important for Growth and Survival of Human Embryonic Stem Cells [作者：Peng, SP; Chen, LL; Lei, XX; Yang, L; Lin, HF; Carmichael, GG; Huang, YQ,期刊：Stem Cells, 页码：496-504 , 文章类型： Article，,卷期：2011年29-3] Lin28 inhibits the expression of let-7 microRNAs but also exhibits let-7-independent functions. Using immunoprecipitation and deep sequencing, we show here that Lin28 preferentially associates with a small subset of cell... MyoD Gene Suppression by Oct4 Is Required for Reprogramming in Myoblasts to Produce Induced Pluripotent Stem Cells [作者：Watanabe, S; Hirai, H; Asakura, Y; Tastad, C; Verma, M; Keller, C; Dutton, JR; Asakura, A,期刊：Stem Cells, 页码：505-516 , 文章类型： Article，,卷期：2011年29-3] Expression of the four transcription factors, that is, Oct4, Sox2, cMyc, and Klf4 has been shown to generate induced pluripotent stem cells (iPSCs) from many types of specialized differentiated somatic cells. It remains ... Production of Mouse Embryonic Stem Cell Lines from Maturing Oocytes by Direct Conversion of Meiosis into Mitosis [作者：Fulka, H; Hirose, M; Inoue, K; Ogonuki, N; Wakisaka, N; Matoba, S; Ogura, A; Mosko, T; Kott, T; Fulka, J,期刊：Stem Cells, 页码：517-527 , 文章类型： Article，,卷期：2011年29-3] ESCs are most commonly derived from embryos originating from oocytes that reached metaphase II. We describe here a novel approach where ESCs with all pluripotency parameters were established from oocytes in which metapha... Wnt Signaling Regulates Symmetry of Division of Neural Stem Cells in the Adult Brain and in Response to Injury [作者：Piccin, D; Morshead, CM,期刊：Stem Cells, 页码：528-538 , 文章类型： Article，,卷期：2011年29-3] Neural stem cells comprise a small population of subependymal cells in the adult brain that divide asymmetrically under baseline conditions to maintain the stem cell pool and divide symmetrically in response to injury to... The Er71 Is an Important Regulator of Hematopoietic Stem Cells in Adult Mice [作者：Lee, D; Kim, T; Lim, DS,期刊：Stem Cells, 页码：539-548 , 文章类型： Article，,卷期：2011年29-3] The Ets transcription factor Er71 is an important regulator of endothelial and hematopoietic development during mammalian embryogenesis. However, the role of Er71 in adult hematopoiesis has remained unknown. We now first... Brief Report: Combined Chemical Treatment Enables Oct4-Induced Reprogramming from Mouse Embryonic Fibroblasts [作者：Yuan, X; Wan, HF; Zhao, XY; Zhu, SY; Zhou, Q; Ding, S,期刊：Stem Cells, 页码：549-553 , 文章类型： Article，,卷期：2011年29-3] It has been established that exogenous expression of four transcription factors (Oct4, Klf4, Sox2, and c-Myc) can reprogram mammalian somatic cells to pluripotent states. Further studies demonstrated that such induced pl... Law, Ethics, Religion, and Clinical Translation in the 21st Century-A Conversation with Anthony D. Ho [作者：Lako, M; Trounson, AO; Daher, S; Ho, AD,期刊：Stem Cells, 页码：387-388 , 文章类型： Editorial Material，,卷期：2011年29-3] Concise Review: Neutral Endopeptidase (CD10): A Multifaceted Environment Actor in Stem Cells, Physiological Mechanisms, and Cancer [作者：Maguer-Satta, V; Besancon, R; Bachelard-Cascales, E,期刊：Stem Cells, 页码：389-396 , 文章类型： Review，,卷期：2011年29-3] CD10 is a remarkable member of the major class of widely expressed cell surface proteins, endopeptidases. First identified in leukemia as a tumor-specific antigen (common acute lymphoblastic leukemia antigen), CD10 has b... Concise Review: Mesenchymal Tumors: When Stem Cells Go Mad [作者：Mohseny, AB; Hogendoorn, PCW,期刊：Stem Cells, 页码：397-403 , 文章类型： Review，,卷期：2011年29-3] Sarcomas are nonepithelial, nonhematopoietic malignant tumors that arise from the embryonic mesoderm. Despite their rarity, less than 10% of all cancers, sarcomas are accountable for relatively high morbidity and mortali... Concise Review: Human Adipose-Derived Stem Cells: Separating Promise from Clinical Need [作者：Locke, M; Feisst, V; Dunbar, R,期刊：Stem Cells, 页码：404-411 , 文章类型： Review，,卷期：2011年29-3] Human adipose-derived stem cells (ASCs) have become an increasing interest to both stem cell biologists and clinicians because of their potential to differentiate into adipogenic, osteogenic, chondrogenic, and other mese...