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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共20条记录   An Important Role for CDK2 in G1 to S Checkpoint Activation and DNA Damage Response in Human Embryonic Stem Cells [作者：Neganova, I; Vilella, F; Atkinson, SP; Lloret, M; Passos, JF; von Zglinicki, T; O'Connor, JE; Burks, D; Jones, R; Armstrong, L; Lako, M,期刊：Stem Cells, 页码：651-659 , 文章类型： Article，,卷期：2011年29-4] A precise understanding of mechanisms used by human embryonic stem cells (hESCs) to maintain genomic integrity is very important for their potential clinical applications. The G1 checkpoint serves to protect genomic inte... Promyelocytic Leukemia Protein in Retinoic Acid-Induced Chromatin Remodeling of Oct4 Gene Promoter [作者：Chuang, YS; Huang, WH; Park, SW; Persaud, SD; Hung, CH; Ho, PC; Wei, LN,期刊：Stem Cells, 页码：660-669 , 文章类型： Article，,卷期：2011年29-4] Promyelocytic leukemia (Pml) protein is required for Oct4 gene expression and the maintenance of its open chromatin conformation in stem cells. In proliferating stem cells, Pml-nuclear body, along with transcription fact... Functional Effects of Adult Human Olfactory Stem Cells on Early-Onset Sensorineural Hearing Loss [作者：Pandit, SR; Sullivan, JM; Egger, V; Borecki, AA; Oleskevich, S,期刊：Stem Cells, 页码：670-677 , 文章类型： Article，,卷期：2011年29-4] Transplantation of exogenous stem cells has been proposed as a treatment to prevent or reverse sensorineural hearing loss. Here, we investigate the effects of transplantation of adult human olfactory mucosa-derived stem ... Wnt and Notch Pathways Have Interrelated Opposing Roles on Prostate Progenitor Cell Proliferation and Differentiation [作者：Shahi, P; Seethammagari, MR; Valdez, JM; Xin, L; Spencer, DM,期刊：Stem Cells, 页码：678-688 , 文章类型： Article，,卷期：2011年29-4] Tissue stem cells are capable of both self-renewal and differentiation to maintain a constant stem cell population and give rise to the plurality of cells within a tissue. Wnt signaling has been previously identified as ... Transforming Growth Factor beta-Mediated Sox10 Suppression Controls Mesenchymal Progenitor Generation in Neural Crest Stem Cells [作者：John, N; Cinelli, P; Wegner, M; Sommer, L,期刊：Stem Cells, 页码：689-699 , 文章类型： Article，,卷期：2011年29-4] During vertebrate development, neural crest stem cells (NCSCs) give rise to neural cells of the peripheral nervous system and to a variety of mesenchymal cell types, including smooth muscle, craniofacial chondrocytes, an... Conditional Activation of Bmi1 Expression Regulates Self-renewal, Apoptosis, and Differentiation of Neural Stem/Progenitor Cells In Vitro and In Vivo [作者：Yadirgi, G; Leinster, V; Acquati, S; Bhagat, H; Shakhova, O; Marino, S,期刊：Stem Cells, 页码：700-712 , 文章类型： Article，,卷期：2011年29-4] The Polycomb group protein Bmi1 is a key regulator of self-renewal of embryonic and adult central nervous system stem cells, and its overexpression has been shown to occur in several types of brain tumors. In a Cre/LoxP-... Cdk6-Dependent Regulation of G(1) Length Controls Adult Neurogenesis [作者：Beukelaers, P; Vandenbosch, R; Caron, N; Nguyen, L; Belachew, S; Moonen, G; Kiyokawa, H; Barbacid, M; Santamaria, D; Malgrange, B,期刊：Stem Cells, 页码：713-724 , 文章类型： Article，,卷期：2011年29-4] The presence of neurogenic precursors in the adult mammalian brain is now widely accepted, but the mechanisms coupling their proliferation with the onset of neuronal differentiation remain unknown. Here, we unravel the m... The Pathology of Bleomycin-Induced Fibrosis Is Associated with Loss of Resident Lung Mesenchymal Stem Cells That Regulate Effector T-Cell Proliferation [作者：Jun, D; Garat, C; West, J; Thorn, N; Chow, K; Cleaver, T; Sullivan, T; Torchia, EC; Childs, C; Shade, T; Tadjali, M; Lara, A; Nozik-Grayck, E; Malkoski, S; Sorrentino, B; Meyrick, B; Klemm, D; Rojas, M; Wagner, DH; Majka, SM,期刊：Stem Cells, 页码：725-735 , 文章类型： Article，,卷期：2011年29-4] Tissue-resident mesenchymal stem cells (MSCs) are important regulators of tissue repair or regeneration, fibrosis, inflammation, angiogenesis, and tumor formation. Here, we define a population of resident lung MSCs (luMS... Brief Report: Ectopic Expression of Nup98-HoxA10 Augments Erythroid Differentiation of Human Embryonic Stem Cells [作者：Ji, JF; Risueno, RM; Hong, S; Allan, D; Rosten, P; Humphries, K; Bhatia, M,期刊：Stem Cells, 页码：736-741 , 文章类型： Article，,卷期：2011年29-4] Hox genes encode highly conserved transcription factors that have been implicated in hematopoietic development and self-renewal of hematopoietic stem cells (HSCs) and hematopoietic development. The potency of NUP98-HOX-A... Concise Review: Induced Pluripotent Stem Cells and Lineage Reprogramming: Prospects for Bone Regeneration [作者：Illich, DJ; Demir, N; Stojkovic, M; Scheer, M; Rothamel, D; Neugebauer, J; Hescheler, J; Zoller, JE,期刊：Stem Cells, 页码：555-563 , 文章类型： Review，,卷期：2011年29-4] Bone tissue for transplantation therapies is in high demand in clinics. Osteodegenerative diseases, in particular, osteoporosis and osteoarthritis, represent serious public health issues affecting a respectable proportio... Concise Review: Stem Cells for the Treatment of Cerebellar-Related Disorders [作者：Erceg, S; Moreno-Manzano, V; Garita-Hernandez, M; Stojkovic, M; Bhattacharya, SS,期刊：Stem Cells, 页码：564-569 , 文章类型： Review，,卷期：2011年29-4] Embryonic neural transplants have become clinically relevant over the past 25 years for their possible application in the treatment of cerebellum-related neurodegenerative diseases. While highlighting the important role ... Concise Review: Aldehyde Dehydrogenase Bright Stem and Progenitor Cell Populations from Normal Tissues: Characteristics, Activities, and Emerging Uses in Regenerative Medicine [作者：Balber, AE,期刊：Stem Cells, 页码：570-575 , 文章类型： Review，,卷期：2011年29-4] Flow cytometry has been used to detect cells that express high levels of the aldehyde dehydrogenase activity in normal tissues. Such ALDH bright (ALDHbr) cell populations have been sorted from human cord blood, bone marr... Concise Review: Adipose-Derived Stromal Cells for Skeletal Regenerative Medicine [作者：Levi, B; Longaker, MT,期刊：Stem Cells, 页码：576-582 , 文章类型： Review，,卷期：2011年29-4] As the average age of the population grows, the incidence of osteoporosis and skeletal diseases continues to rise. Current treatment options for skeletal repair include immobilization, rigid fixation, alloplastic materia... Concise Review: Culture Mediated Changes in Fate and/or Potency of Stem Cells [作者：Roobrouck, VD; Vanuytsel, K; Verfaillie, CM,期刊：Stem Cells, 页码：583-589 , 文章类型： Review，,卷期：2011年29-4] Although Gurdon demonstrated already in 1958 that the nucleus of intestinal epithelial cells could be reprogrammed to give rise to adult frogs, the field of cellular reprogramming has only recently come of age with the d... Combination of a Ptgs2 Inhibitor and an Epidermal Growth Factor Receptor-Signaling Inhibitor Prevents Tumorigenesis of Oligodendrocyte Lineage-Derived Glioma-Initiating Cells [作者：Hide, T; Takezaki, T; Nakatani, Y; Nakamura, H; Kuratsu, J; Kondo, T,期刊：Stem Cells, 页码：590-599 , 文章类型： Article，,卷期：2011年29-4] Recent findings have demonstrated that malignant tumors, including glioblastoma multiforme (GBM), contain cancer-initiating cells (CICs; also known as cancer stem cells), which self-renew and are malignant. However, it r... Molecular and Functional Characterizations of Gastrula Organizer Cells Derived from Human Embryonic Stem Cells [作者：Sharon, N; Mor, I; Golan-lev, T; Fainsod, A; Benvenisty, N,期刊：Stem Cells, 页码：600-608 , 文章类型： Article，,卷期：2011年29-4] The Spemann-Mangold organizer is the structure that provides the signals, which initiate pattern formation in the developing vertebrate embryo, affecting the main body axes. Very little is known about axial induction in ...