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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共20条记录   Aneuploidy in Human Spermatozoa [作者：Templado, C; Vidal, F; Estop, A,期刊：Cytogenetic and Genome Research, 页码：91-99 , 文章类型： Article，,卷期：2011年133-1-2] We reviewed the frequency and distribution of disomy in spermatozoa obtained by multicolor-FISH analysis on decondensed sperm nuclei in (a) healthy men, (b) fathers of aneuploid offspring of paternal origin and (c) indiv... Aneuploidy and DNA Fragmentation in Sperm of Carriers of a Constitutional Chromosomal Abnormality [作者：Perrin, A; Basinko, A; Douet-Guilbert, N; Gueganic, N; Le Bris, MJ; Amice, V; De Braekeleer, M; Morel, F,期刊：Cytogenetic and Genome Research, 页码：100-106 , 文章类型： Article，,卷期：2011年133-1-2] Among various causes responsible for infertility, it has been admitted for a long time that male infertility can be due to impaired spermatogenesis and/or balanced structural chromosomal abnormalities. Sperm DNA fragment... Chromosome Abnormalities in the Human Oocyte [作者：Fragouli, E; Wells, D; Delhanty, JDA,期刊：Cytogenetic and Genome Research, 页码：107-118 , 文章类型： Article，,卷期：2011年133-1-2] Aneuploidy is the most commonly occurring type of chromosome abnormality and the most significant clinically. It arises mostly due to segregation errors taking place during female meiosis and is also closely associated w... Whole-Chromosome Aneuploidy Analysis in Human Oocytes: Focus on Comparative Genomic Hybridization [作者：Obradors, A; Rius, M; Daina, G; Ramos, L; Benet, J; Navarro, J,期刊：Cytogenetic and Genome Research, 页码：119-126 , 文章类型： Article，,卷期：2011年133-1-2] The study of aneuploidy in human oocytes, discarded from IVF cycles, has provided a better understanding of the incidence of aneuploidy of female origin and the responsible mechanisms. Comparative genomic hybridization (... Predisposition to Aneuploidy in the Oocyte [作者：Vialard, F; Boitrelle, F; Molina-Gomes, D; Selva, J,期刊：Cytogenetic and Genome Research, 页码：127-135 , 文章类型： Article，,卷期：2011年133-1-2] While the incidence of predisposition to aneuploidy in the oocyte increases with age, there is also evidence of increased incidence in young women with recurrent miscarriage, recurrent aneuploidy, or recurrent implantati... Inherited Aneuploidy: Germline Mosaicism [作者：Delhanty, JDA,期刊：Cytogenetic and Genome Research, 页码：136-140 , 文章类型： Article，,卷期：2011年133-1-2] Germline mosaicism has been thought to be a rare cause of aneuploidy in the human population. Recent evidence from cytological and population studies suggests otherwise. Approximately 5% of young couples with a Down synd... Aneuploidy in the Human Cleavage Stage Embryo [作者：Mantzouratou, A; Delhanty, JDA,期刊：Cytogenetic and Genome Research, 页码：141-148 , 文章类型： Article，,卷期：2011年133-1-2] The cleavage stage embryo (days 1-3) stands out due to the high level of chromosomal anomalies, especially mosaicism that arises prior to global embryonic genome activation. Molecular cytogenetic studies show that an ave... Aneuploidy in the Human Blastocyst [作者：Fragouli, E; Wells, D,期刊：Cytogenetic and Genome Research, 页码：149-159 , 文章类型： Article，,卷期：2011年133-1-2] Studies of human cleavage stage embryos, 3 days after fertilization of the oocyte, have revealed remarkably high levels of chromosome abnormality. In addition to meiotic errors derived from the gametes, principally the o... The Human Cleavage Stage Embryo Is a Cradle of Chromosomal Rearrangements [作者：Voet, T; Vanneste, E; Vermeesch, JR,期刊：Cytogenetic and Genome Research, 页码：160-168 , 文章类型： Article，,卷期：2011年133-1-2] The first cell cycles following in vitro fertilization (IVF) of human gametes are prone to chromosome instability. Many, but often not all, blastomeres of an embryo acquire a genetic makeup during cleavage that is not re... Mosaic Aneuploidy in Early Fetal Losses [作者：Lebedev, I,期刊：Cytogenetic and Genome Research, 页码：169-183 , 文章类型： Article，,卷期：2011年133-1-2] Chromosomal mosaicism is the presence of 2 or more cell lines with different karyotypes in the same individual. Mosaic karyotypes are a remarkable feature of early stages of human embryo development. They result from mit... Sporadic Aneuploidy in PHA-Stimulated Lymphocytes of Trisomies 21, 18, and 13 [作者：Reish, O; Regev, M; Kanesky, A; Girafi, S; Mashevich, M,期刊：Cytogenetic and Genome Research, 页码：184-189 , 文章类型： Article，,卷期：2011年133-1-2] Following the observation detected in a previous study that X chromosome monosomy in Turner's syndrome genotypes was associated with a sporadic loss and/or gain of other chromosomes, we studied here whether this instabil... Mechanisms of Whole Chromosome Gains in Tumors - Many Answers to a Simple Question [作者：Gisselsson, D,期刊：Cytogenetic and Genome Research, 页码：190-201 , 文章类型： Article，,卷期：2011年133-1-2] Whole chromosome gain is the most common type of gross genomic abnormality observed in human tumors. It is particularly frequent in lympho-haematopoietic and embryonic neoplasms, where trisomies and tetrasomies are typic... Meiotic Studies of a 38,XY/39,XXY Mosaic Boar [作者：Pinton, A; Barasc, H; Letron, IR; Bordedebat, M; Mary, N; Massip, K; Bonnet, N; Calgaro, A; Dudez, AM; Feve, K; Riquet, J; Yerle, M; Ducos, A,期刊：Cytogenetic and Genome Research, 页码：202-208 , 文章类型： Article，,卷期：2011年133-1-2] Klinefelter's syndrome (KS) is the most common sex chromosome abnormality identified in human males. This syndrome is generally associated with infertility. Men with KS may have a 47, XXY or a 46, XY/47, XXY karyotype. S... New Insights into the Genetic Regulation of Homologue Disjunction in Mammalian Oocytes [作者：Homer, H,期刊：Cytogenetic and Genome Research, 页码：209-222 , 文章类型： Article，,卷期：2011年133-1-2] Mammalian oocytes execute a unique meiotic programme involving 2 arrest stages and an unusually protracted preamble to chromosome segregation during the first meiotic division (meiosis I). How mammalian oocytes successfu... Sister Chromatid Cohesion Control and Aneuploidy [作者：Barbero, JL,期刊：Cytogenetic and Genome Research, 页码：223-233 , 文章类型： Article，,卷期：2011年133-1-2] Apart from a personal tragedy, could Down syndrome, cancer and infertility possibly have something in common? Are there links between a syndrome with physical and mental problems, a tumor growing out of control and the i... The Role of Shugoshin in Meiotic Chromosome Segregation [作者：Clift, D; Marston, AL,期刊：Cytogenetic and Genome Research, 页码：234-242 , 文章类型： Article，,卷期：2011年133-1-2] During meiosis, DNA replication is followed by 2 successive chromosome segregation events, resulting in the production of gametes with a haploid number of chromosomes from a diploid precursor cell. Faithful chromosome se...