- Specific replication origins promote DNA amplification in fission yeast
[作者:Kiang, L; Heichinger, C; Watt, S; Bahler, J; Nurse, P,期刊:Journal of cell science, 页码:3047-3051 , 文章类型: Article,,卷期:2010年123-18]
- To ensure equal replication of the genome in every eukaryotic cell cycle, replication origins fire only once each S phase and do not fire after passive replication. Failure in these controls can lead to local amplificati...
- Chemokine expression and control of muscle cell migration during myogenesis
[作者:Griffin, CA; Apponi, LH; Long, KK; Pavlath, GK,期刊:Journal of cell science, 页码:3052-3060 , 文章类型: Article,,卷期:2010年123-18]
- Adult regenerative myogenesis is vital for restoring normal tissue structure after muscle injury. Muscle regeneration is dependent on progenitor satellite cells, which proliferate in response to injury, and their progeny...
- beta-Dystroglycan binds caveolin-1 in smooth muscle: a functional role in caveolae distribution and Ca2+ release
[作者:Sharma, P; Ghavami, S; Stelmack, GL; McNeill, KD; Mutawe, MM; Klonisch, T; Unruh, H; Halayko, AJ,期刊:Journal of cell science, 页码:3061-3070 , 文章类型: Article,,卷期:2010年123-18]
- The dystrophin-glycoprotein complex (DGC) links the extracellular matrix and actin cytoskeleton. Caveolae form membrane arrays on smooth muscle cells; we investigated the mechanism for this organization. Caveolin-1 and b...
- The myotubularin phosphatase MTMR4 regulates sorting from early endosomes
[作者:Naughtin, MJ; Sheffield, DA; Rahman, P; Hughes, WE; Gurung, R; Stow, JL; Nandurkar, HH; Dyson, JM; Mitchell, CA,期刊:Journal of cell science, 页码:3071-3083 , 文章类型: Article,,卷期:2010年123-18]
- Phosphatidylinositol 3-phosphate [PtdIns(3)P] regulates endocytic trafficking and the sorting of receptors through early endosomes, including the rapid recycling of transferrin (Tfn). However, the phosphoinositide phosph...
- Phosphorylation of STIM1 at ERK1/2 target sites modulates store-operated calcium entry
[作者:Pozo-Guisado, E; Campbell, DG; Deak, M; Alvarez-Barrientos, A; Morrice, NA; Alvarez, IS; Alessi, DR; Martin-Romero, FJ,期刊:Journal of cell science, 页码:3084-3093 , 文章类型: Article,,卷期:2010年123-18]
- Store-operated calcium entry (SOCE) is an important Ca2+ entry pathway that regulates many cell functions. Upon store depletion, STIM1, a transmembrane protein located in the endoplasmic reticulum (ER), aggregates and re...
- Isolation of a small vasohibin-binding protein (SVBP) and its role in vasohibin secretion
[作者:Suzuki, Y; Kobayashi, M; Miyashita, H; Ohta, H; Sonoda, H; Sato, Y,期刊:Journal of cell science, 页码:3094-3101 , 文章类型: Article,,卷期:2010年123-18]
- Upon stimulation with angiogenic factors, vascular endothelial cells (ECs) secrete a negative-feedback regulator of angiogenesis, vasohibin-1 (VASH1). Because VASH1 lacks a classical signal sequence, it is not clear how ...
- The fibroblast-derived paracrine factor neuregulin-1 has a novel role in regulating the constitutive color and melanocyte function in human skin
[作者:Choi, W; Wolber, R; Gerwat, W; Mann, T; Batzer, J; Smuda, C; Liu, HF; Kolbe, L; Hearing, VJ,期刊:Journal of cell science, 页码:3102-3111 , 文章类型: Article,,卷期:2010年123-18]
- Interactions between melanocytes and neighboring cells in the skin are important in regulating skin color in humans. We recently demonstrated that the less pigmented and thicker skin on the palms and soles is regulated b...
- Formation of extra centrosomal structures is dependent on beta-catenin
[作者:Bahmanyar, S; Guiney, EL; Hatch, EM; Nelson, WJ; Barth, AIM,期刊:Journal of cell science, 页码:3125-3135 , 文章类型: Article,,卷期:2010年123-18]
- beta-Catenin has important roles in cell-cell adhesion and in the regulation of gene transcription. Mutations that stabilize beta-catenin are common in cancer, but it remains unclear how these mutations contribute to can...
- Leiomodin-2 is an antagonist of tropomodulin-1 at the pointed end of the thin filaments in cardiac muscle
[作者:Tsukada, T; Pappas, CT; Moroz, N; Antin, PB; Kostyukova, AS; Gregorio, CC,期刊:Journal of cell science, 页码:3136-3145 , 文章类型: Article,,卷期:2010年123-18]
- Regulation of actin filament assembly is essential for efficient contractile activity in striated muscle. Leiomodin is an actin-binding protein and homolog of the pointed-end capping protein, tropomodulin. These proteins...
- Growth differentiation factor 9 signaling requires ERK1/2 activity in mouse granulosa and cumulus cells
[作者:Sasseville, M; Ritter, LJ; Nguyen, TM; Liu, F; Mottershead, DG; Russell, DL; Gilchrist, RB,期刊:Journal of cell science, 页码:3166-3176 , 文章类型: Article,,卷期:2010年123-18]
- Ovarian folliculogenesis is driven by the combined action of endocrine cues and paracrine factors. The oocyte secretes powerful mitogens, such as growth differentiation factor 9 (GDF9), that regulate granulosa cell proli...
- Regulation of mixed-lineage kinase activation in JNK-dependent morphogenesis
[作者:Garlena, RA; Gonda, RL; Green, AB; Pileggi, RM; Stronach, B,期刊:Journal of cell science, 页码:3177-3188 , 文章类型: Article,,卷期:2010年123-18]
- Normal cells respond appropriately to various signals, while sustaining proper developmental programs and tissue homeostasis. Inappropriate signal reception, response or attenuation, can upset the normal balance of signa...
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