- Heterologous expression reveals distinct enzymatic activities of two DOT1 histone methyltransferases of Trypanosoma brucei
[作者：Frederiks, F; van Welsem, T; Oudgenoeg, G; Heck, AJR; Janzen, CJ; van Leeuwen, F,期刊：Journal of cell science, 页码：4019-4023 , 文章类型： Article，,卷期：2010年123-23]
- Dot1 is a highly conserved methyltransferase that modifies histone H3 on the nucleosome core surface. In contrast to yeast, flies, and humans where a single Dot1 enzyme is responsible for all methylation of H3 lysine 79 ...
- Phosphoinositides differentially regulate bacterial uptake and Nramp1-induced resistance to Legionella infection in Dictyostelium
[作者：Peracino, B; Balest, A; Bozzaro, S,期刊：Journal of cell science, 页码：4039-4051 , 文章类型： Article，,卷期：2010年123-23]
- Membrane phosphatidylinositides recruit cytosolic proteins to regulate phagocytosis, macropinocytosis and endolysosomal vesicle maturation. Here, we describe effects of inactivation of PI3K, PTEN or PLC on Escherichia co...
- Control of Gliotactin localization and levels by tyrosine phosphorylation and endocytosis is necessary for survival of polarized epithelia
[作者：Padash-Barmchi, M; Browne, K; Sturgeon, K; Jusiak, B; Auid, VJ,期刊：Journal of cell science, 页码：4052-4062 , 文章类型： Article，,卷期：2010年123-23]
- The tricellular junction (TCJ) forms at the convergence of bicellular junctions from three adjacent cells in polarized epithelia and is necessary for maintaining the transepithelial barrier. In the fruitfly Drosophila, t...
- Distance between homologous chromosomes results from chromosome positioning constraints
[作者：Heride, C; Ricoul, M; Kieu, K; von Hase, J; Guillemot, V; Cremer, C; Dubrana, K; Sabatier, L,期刊：Journal of cell science, 页码：4063-4075 , 文章类型： Article，,卷期：2010年123-23]
- The organization of chromosomes is important for various biological processes and is involved in the formation of rearrangements often observed in cancer. In mammals, chromosomes are organized in territories that are rad...
- REG gamma modulates p53 activity by regulating its cellular localization
[作者：Liu, JA; Yu, GW; Zhao, YY; Zhao, DP; Wang, Y; Wang, L; Liu, JA; Li, L; Zeng, Y; Dang, YY; Wang, CG; Gao, GA; Long, WW; Lonard, DM; Qiao, SL; Tsai, MJ; Zhang, BH; Luo, HL; Li, XT,期刊：Journal of cell science, 页码：4076-4084 , 文章类型： Article，,卷期：2010年123-23]
- The proteasome activator REG gamma mediates a shortcut for the destruction of intact mammalian proteins. The biological roles of REG gamma and the underlying mechanisms are not fully understood. Here we provide evidence ...
- The Rab GTPase Ypt7 is linked to retromer-mediated receptor recycling and fusion at the yeast late endosome
[作者：Balderhaar, HJK; Arlt, H; Ostrowicz, C; Brocker, C; Sundermann, F; Brandt, R; Babst, M; Ungermann, C,期刊：Journal of cell science, 页码：4085-4094 , 文章类型： Article，,卷期：2010年123-23]
- Organelles of the endomembrane system need to counterbalance fission and fusion events to maintain their surface-to-volume ratio. At the late mammalian endosome, the Rab GTPase Rab7 is a major regulator of fusion, wherea...
- Dampened activity of E2F1-DP and Myb-MuvB transcription factors in Drosophila endocycling cells
[作者：Maqbool, SB; Mehrotra, S; Kolpakas, A; Durden, C; Zhang, BQ; Zhong, H; Calvi, BR,期刊：Journal of cell science, 页码：4095-4106 , 文章类型： Article，,卷期：2010年123-23]
- The endocycle is a variant cell cycle comprised of alternating gap (G) and DNA synthesis (S) phases (endoreplication) without mitosis (M), which results in DNA polyploidy and large cell size. Endocycles occur widely in n...
- Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner in Pichia pastoris
[作者：Tamura, N; Oku, M; Sakai, Y,期刊：Journal of cell science, 页码：4107-4116 , 文章类型： Article，,卷期：2010年123-23]
- Atg8 is a ubiquitin-like protein that is required, along with its lipidation system, for autophagy in all eukaryotic cells. The lipidated form of Atg8 is anchored on the autophagosomal membrane during autophagy. Here, we...
- Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity
[作者：Cho, K; Vaught, TG; Ji, H; Gu, DM; Papasakelariou-Yared, C; Horstmann, N; Jennings, JM; Lee, M; Sevilla, LM; Kloc, M; Reynolds, AB; Watt, FM; Brennan, RG; Kowalczyk, AP; McCrea, PD,期刊：Journal of cell science, 页码：4128-4144 , 文章类型： Article，,卷期：2010年123-23]
- In common with other p120-catenin subfamily members, Xenopus ARVCF (xARVCF) binds cadherin cytoplasmic domains to enhance cadherin metabolic stability or, when dissociated, modulates Rho-family GTPases. We report here th...
- TNF alpha-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NF kappa B signaling
[作者：Amasheh, M; Fromm, A; Krug, SM; Amasheh, S; Andres, S; Zeitz, M; Fromm, M; Schulzke, JD,期刊：Journal of cell science, 页码：4145-4155 , 文章类型： Article，,卷期：2010年123-23]
- TNF alpha-mediated tight junction defects contribute to diarrhea in inflammatory bowel diseases (IBDs). In our study, the signaling pathways of the TNF alpha effect on barrier- or pore-forming claudins were analyzed in H...
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