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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共24条记录   Genetic Basis of Inherited Macular Dystrophies and Implications for Stem Cell Therapy [作者：Mellough, CB; Steel, DHW; Lako, M,期刊：Stem Cells, 页码：2833-2845 , 文章类型： Review，,卷期：2009年27-11] Untreatable hereditary macular dystrophy (HMD) presents a major burden to society in terms of the resulting patient disability and the cost to the healthcare provision system. HMD results in central vision loss in humans... CARM1 is Required in Embryonic Stem Cells to Maintain Pluripotency and Resist Differentiation [作者：Wu, Q; Bruce, AW; Jedrusik, A; Ellis, PD; Andrews, RM; Langford, CF; Glover, DM; Zernicka-Goetz, M,期刊：Stem Cells, 页码：2637-2645 , 文章类型： Article，,卷期：2009年27-11] Histone H3 methylation at R17 and R26 recently emerged as a novel epigenetic mechanism regulating pluripotency in mouse embryos. Blastomeres of four-cell embryos with high H3 methylation at these sites show unrestricted ... Differentiation of Neural Progenitor Cells in a Microfluidic Chip-Generated Cytokine Gradient [作者：Park, JY; Kim, SK; Woo, DH; Lee, EJ; Kim, JH; Lee, SH,期刊：Stem Cells, 页码：2646-2654 , 文章类型： Article，,卷期：2009年27-11] In early embryonic development, spatial gradients of diffusible signaling molecules play important roles in controlling differentiation of cell types or arrays in diverse tissues. Thus, the concentration of exogenous cyt... Signaling Pathways Controlling Pluripotency and Early Cell Fate Decisions of Human Induced Pluripotent Stem Cells [作者：Vallier, L; Touboul, T; Brown, S; Cho, C; Bilican, B; Alexander, M; Cedervall, J; Chandran, S; Ahrlund-Richter, L; Weber, A; Pedersen, RA,期刊：Stem Cells, 页码：2655-2666 , 文章类型： Article，,卷期：2009年27-11] Human pluripotent stem cells from embryonic origins and those generated from reprogrammed somatic cells share many characteristics, including indefinite proliferation and a sustained capacity to differentiate into a wide... Adenoviral Gene Delivery Can Reprogram Human Fibroblasts to Induced Pluripotent Stem Cells [作者：Zhou, WB; Freed, CR,期刊：Stem Cells, 页码：2667-2674 , 文章类型： Article，,卷期：2009年27-11] Mouse and human fibroblasts have been transformed into induced pluripotent stem (iPS) cells by retroviral transduction or plasmid transfection with four genes. Unfortunately, viral and plasmid DNA incorporation into chro... Bioluminescent Imaging Demonstrates That Transplanted Human Embryonic Stem Cell-Derived CD34(+) Cells Preferentially Develop into Endothelial Cells [作者：Tian, XH; Hexum, MK; Penchev, VR; Taylor, RJ; Shultz, LD; Kaufman, DS,期刊：Stem Cells, 页码：2675-2685 , 文章类型： Article，,卷期：2009年27-11] Human embryonic stem cells (hESCs) provide an important resource for novel regenerative medicine therapies and have been used to derive diverse cell populations, including hematopoietic and endothelial cells. However, it... Clone- and Gene-Specific Aberrations of Parental Imprinting in Human Induced Pluripotent Stem Cells [作者：Pick, M; Stelzer, Y; Bar-Nur, O; Mayshar, Y; Eden, A; Benvenisty, N,期刊：Stem Cells, 页码：2686-2690 , 文章类型： Article，,卷期：2009年27-11] Genomic imprinting is an epigenetic phenomenon whereby genes are expressed in a monoallelic manner, which is inherited either maternally or paternally. Expression of imprinted genes has been examined in human embryonic s... Lsh Participates in DNA Methylation and Silencing of Stem Cell Genes [作者：Xi, SC; Geiman, TM; Briones, V; Tao, YG; Xu, H; Muegge, K,期刊：Stem Cells, 页码：2691-2702 , 文章类型： Article，,卷期：2009年27-11] Transcriptional control of stem cell genes is a critical step in differentiation of embryonic stem cells and in reprogramming of somatic cells into stem cells. Here we report that Lsh, a regulator of repressive chromatin... Insulin but Not Glucagon Gene is Silenced in Human Pancreas-Derived Mesenchymal Stem Cells [作者：Wilson, LM; Wong, SHK; Yu, NP; Geras-Raaka, E; Raaka, BM; Gershengorn, MC,期刊：Stem Cells, 页码：2703-2711 , 文章类型： Article，,卷期：2009年27-11] We previously characterized human islet-derived precursor cells (hIPCs) as a specific type of mesenchymal stem cell capable of differentiating to insulin (INS)- and glucagon (GCG)-expressing cells. However, during prolif... Adiponectinemia Controls Pro-Angiogenic Cell Therapy [作者：Eren, P; Camus, S; Matrone, G; Ebrahimian, TG; Francois, D; Tedgui, A; Silvestre, JS; Blanc-Brude, OP,期刊：Stem Cells, 页码：2712-2721 , 文章类型： Article，,卷期：2009年27-11] Angiogenic cell therapy with the transplantation of endothelial progenitor cells (EPC) or bone marrow mononuclear cells (BM-MNC) receives considerable attention as an approach to revascularize ischemic tissues. Adiponect... A Mesenchymal-Like ZEB1(+) Niche Harbors Dorsal Radial Glial Fibrillary Acidic Protein-Positive Stem Cells in the Spinal Cord [作者：Sabourin, JC; Ackema, KB; Ohayon, D; Guichet, PO; Perrin, FE; Garces, A; Ripoll, C; Charite, J; Simonneau, L; Kettenmann, H; Zine, A; Privat, A; Valmier, J; Pattyn, A; Hugnot, JP,期刊：Stem Cells, 页码：2722-2733 , 文章类型： Article，,卷期：2009年27-11] In humans and rodents the adult spinal cord harbors neural stem cells located around the central canal. Their identity, precise location, and specific signaling are still ill-defined and controversial. We report here on ... Mesenchymal Stem Cells Promote Matrix Metalloproteinase Secretion by Cardiac Fibroblasts and Reduce Cardiac Ventricular Fibrosis After Myocardial Infarction [作者：Mias, C; Lairez, O; Trouche, E; Roncalli, J; Calise, D; Seguelas, MH; Ordener, C; Piercecchi-Marti, MD; Auge, N; Salvayre, AN; Bourin, P; Parini, A; Cussac, D,期刊：Stem Cells, 页码：2734-2743 , 文章类型： Article，,卷期：2009年27-11] Recent studies showed that mesenchymal stem cells (MSCs) transplantation significantly decreased cardiac fibrosis; however, the mechanisms involved in these effects are still poorly understood. In this work, we investiga... Astrocyte Differentiation of Neural Precursor Cells is Enhanced by Retinoic Acid Through a Change in Epigenetic Modification [作者：Asano, H; Aonuma, M; Sanosaka, T; Kohyama, J; Namihira, M; Nakashima, K,期刊：Stem Cells, 页码：2744-2752 , 文章类型： Article，,卷期：2009年27-11] Neurons, astrocytes, and oligodendrocytes-the three major cell types that comprise the central nervous system-are generated from common multipotent neural precursor cells (NPCs). Members of the interleukin-6 family of cy... Human Multipotent Adipose-Derived Stem Cells Differentiate into Functional Brown Adipocytes [作者：Elabd, C; Chiellini, C; Carmona, M; Galitzky, J; Cochet, O; Petersen, R; Penicaud, L; Kristiansen, K; Bouloumie, A; Casteilla, L; Dani, C; Ailhaud, G; Amri, EZ,期刊：Stem Cells, 页码：2753-2760 , 文章类型： Article，,卷期：2009年27-11] In contrast to the earlier contention, adult humans have been shown recently to possess active brown adipose tissue with a potential of being of metabolic significance. Up to now, brown fat precursor cells have not been ... In Vivo Physiological Transdifferentiation of Adult Adipose Cells [作者：De Matteis, R; Zingaretti, MC; Murano, I; Vitali, A; Frontini, A; Giannulis, I; Barbatelli, G; Marcucci, F; Bordicchia, M; Sarzani, R; Raviola, E; Cinti, S,期刊：Stem Cells, 页码：2761-2768 , 文章类型： Article，,卷期：2009年27-11] Grafts of adipose tissue from adult Rosa26 mice from different sites of the body, irrespective of the sex of the donor, share with the mammary fat the property of giving rise to milk-secreting epithelial cells when expos... Numb Promotes an Increase in Skeletal Muscle Progenitor Cells in the Embryonic Somite [作者：Jory, A; Le Roux, I; Gayraud-Morel, B; Rocheteau, P; Cohen-Tannoudji, M; Cumano, A; Tajbakhsh, S,期刊：Stem Cells, 页码：2769-2780 , 文章类型： Article，,卷期：2009年27-11] Multiple cell types arise from cells in the dermomyotome of the somite that express Pax3 and Pax7, and myogenesis is regulated by Notch signaling. The asymmetric cell fate determinant Numb is thought to promote different...