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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共35条记录   Sobemovirus RNA linked to VPg over a threonine residue [作者：Olspert, A; Arike, L; Peil, L; Truve, E,期刊：FEBS Letters, 页码：2979-2985 , 文章类型： Article，,卷期：2011年585-19] Positive sense ssRNA virus genomes from several genera have a viral protein genome-linked (VPg) attached over a phosphodiester bond to the 5' end of the genome. The VPgs of Southern bean mosaic virus (SBMV) and Ryegrass ... Characterization of benzoxaborole-based antifungal resistance mutations demonstrates that editing depends on electrostatic stabilization of the leucyl-tRNA synthetase editing cap [作者：Sarkar, J; Mao, WM; Lincecum, TL; Alley, MRK; Martinis, SA,期刊：FEBS Letters, 页码：2986-2991 , 文章类型： Article，,卷期：2011年585-19] The broad-spectrum benzoxaborole antifungal AN2690 blocks protein synthesis by inhibiting leucyl-tRNA synthetase (LeuRS) via a novel oxaborole tRNA trapping mechanism in the editing site. Herein, one set of resistance mu... MiR-140 is co-expressed with Wwp2-C transcript and activated by Sox9 to target Sp1 in maintaining the chondrocyte proliferation [作者：Yang, J; Qin, SY; Yi, CQ; Ma, G; Zhu, H; Zhou, WR; Xiong, YY; Zhu, XM; Wang, YJ; He, L; Guo, XZ,期刊：FEBS Letters, 页码：2992-2997 , 文章类型： Article，,卷期：2011年585-19] MiR-140 is a microRNA specially involved in chondrogenesis and osteoarthritis pathogenesis. However, its transcriptional regulation and target genes in cartilage development are not fully understood. Here we detected tha... miR-21 targets the tumor suppressor RhoB and regulates proliferation, invasion and apoptosis in colorectal cancer cells [作者：Liu, M; Tang, QL; Qiu, M; Lang, N; Li, MX; Zheng, Y; Bi, F,期刊：FEBS Letters, 页码：2998-3005 , 文章类型： Article，,卷期：2011年585-19] It has become increasingly clear that microRNAs play an important role in many human diseases including cancer. Here, we show that expression of miR-21 in HEK293 and several colorectal cancer cells was found inversely co... Brucella adaptation and survival at the crossroad of metabolism and virulence [作者：Barbier, T; Nicolas, C; Letesson, JJ,期刊：FEBS Letters, 页码：2929-2934 , 文章类型： Review，,卷期：2011年585-19] In vivo bacterial nutrition, i.e. the nature of the metabolic network and substrate( s) used by bacteria within their host, is a fundamental aspect of pathogenic or symbiotic lifestyles. A typical example are the Brucell... Protein oligomerization mediated by the transmembrane carboxyl terminal domain of Bcl-XL [作者：Ospina, A; Lagunas-Martinez, A; Pardo, J; Carrodeguas, JA,期刊：FEBS Letters, 页码：2935-2942 , 文章类型： Article，,卷期：2011年585-19] Bcl-XL is a pro-survival member of the Bcl-2 family that can be found in the outer mitochondrial membrane and in soluble cytosolic homodimers. Bcl-XL can bind pro-apoptotic members of this family preventing them from act... E3 ubiquitin ligase Siah-1 facilitates poly-ubiquitylation and proteasomal degradation of the hepatitis B viral X protein [作者：Zhao, J; Wang, CJ; Wang, J; Yang, XM; Diao, N; Li, Q; Wang, WZ; Xian, LL; Fang, Z; Yu, L,期刊：FEBS Letters, 页码：2943-2950 , 文章类型： Article，,卷期：2011年585-19] Hepatitis B viral X protein (HBx) is a multifunctional transactivator and implicated in hepatitis B virus (HBV) replication and hepatocarcinogenesis. HBx can be ubiquitinated and degraded through ubiquitin-proteasome pat... Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail [作者：Behnke, J; Schneppenheim, J; Koch-Nolte, F; Haag, F; Saftig, P; Schroder, B,期刊：FEBS Letters, 页码：2951-2957 , 文章类型： Article，,卷期：2011年585-19] Signal-peptide-peptidase-like 2A (SPPL2a), an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2. Here, we show that endogenous SPPL2a - in agreement with overexpres... A structural insight into the C-terminal RNA recognition motifs of T-cell intracellular antigen-1 protein [作者：Aroca, A; Diaz-Quintana, A; Diaz-Moreno, I,期刊：FEBS Letters, 页码：2958-2964 , 文章类型： Article，,卷期：2011年585-19] T-cell intracellular antigen-1 (TIA-1) plays a pleiotropic role in cell homeostasis through the regulation of alternative pre-mRNA splicing and mRNA translation by recognising uridine-rich sequences of RNAs. TIA-1 contai... Ago1 and Ago2 differentially affect cell proliferation, motility and apoptosis when overexpressed in SH-SY5Y neuroblastoma cells [作者：Parisi, C; Giorgi, C; Batassa, EM; Braccini, L; Maresca, G; D'agnano, I; Caputo, V; Salvatore, A; Pietrolati, F; Cogoni, C; Catalanotto, C,期刊：FEBS Letters, 页码：2965-2971 , 文章类型： Article，,卷期：2011年585-19] Argonaute are a conserved class of proteins central to the microRNA pathway. We have highlighted a novel and non-redundant function of Ago1 versus Ago2; the two core factors of the miRNA-associated RISC complex. Stable o... Src-stimulated IRTKS phosphorylation enhances cell migration [作者：Chen, G; Li, TT; Zhang, LT; Yi, M; Chen, F; Wang, ZQ; Zhang, X,期刊：FEBS Letters, 页码：2972-2978 , 文章类型： Article，,卷期：2011年585-19] Insulin receptor tyrosine kinase substrate (IRTKS) has been demonstrated to be a scaffold protein involved in plasma membrane deformation and actin cytoskeleton remodeling. IRTKS is tyrosine phosphorylated in response to... Free sphingobases induce RBOHD-dependent reactive oxygen species production in Arabidopsis leaves [作者：Peer, M; Bach, M; Mueller, MJ; Waller, F,期刊：FEBS Letters, 页码：3006-3010 , 文章类型： Article，,卷期：2011年585-19] Sphingolipids are implied in several regulatory processes, including cell death. Levels of the free sphingobase t18:0 (phytosphingosine) increase in Arabidopsis in response to the bacterial pathogen Pseudomonas syringae.... The Y641C mutation of EZH2 alters substrate specificity for histone H3 lysine 27 methylation states [作者：Wigle, TJ; Knutson, SK; Jin, L; Kuntz, KW; Pollock, RM; Richon, VM; Copeland, RA; Scott, MP,期刊：FEBS Letters, 页码：3011-3014 , 文章类型： Article，,卷期：2011年585-19] Mutations at tyrosine 641 (Y641F, Y641N, Y641S and Y641H) in the SET domain of EZH2 have been identified in patients with certain subtypes of non-Hodgkin lymphoma (NHL). These mutations were shown to change the substrate... Yos9, a control protein for misfolded glycosylated and non-glycosylated proteins in ERAD [作者：Benitez, EM; Stolz, A; Wolf, DH,期刊：FEBS Letters, 页码：3015-3019 , 文章类型： Article，,卷期：2011年585-19] The endoplasmic reticulum (ER) is responsible for folding and delivery of secretory proteins to their site of action. One major modification proteins undergo in this organelle is N-glycosylation. Proteins that cannot fol... Structural basis of coagulation factor V recognition for cleavage by RVV-V [作者：Nakayama, D; Ben Ammar, Y; Miyata, T; Takeda, S,期刊：FEBS Letters, 页码：3020-3025 , 文章类型： Article，,卷期：2011年585-19] Russell's viper venom factor V (FV) activator (RVV-V) is a thrombin-like proteinase that specifically cleaves the Arg1545-Ser1546 bond of FV. Here we present the crystal structure of RVV-V in complex with the FV14 peptid... Role of Sch9 in regulating Ras-cAMP signal pathway in Saccharomyces cerevisiae [作者：Zhang, AL; Shen, YB; Gao, WX; Dong, J,期刊：FEBS Letters, 页码：3026-3032 , 文章类型： Article，,卷期：2011年585-19] In Saccharomyces cerevisiae PKA plays a major role in regulating cell growth, metabolism, and stress resistance. We report that Sch9 regulates PKA directly and SCH9 deletion enhances PKA activity by showing that: (1) Bcy...