- Functional interaction between purinergic receptors: Effect of ligands for A(2A) and P2Y(12) receptors on P2Y(1) receptor function
[作者:Suzuki, T; Obara, Y; Moriya, T; Nakata, H; Nakahata, N,期刊:FEBS Letters, 页码:3978-3984 , 文章类型: Article,,卷期:2011年585-24]
- A(2A) adenosine receptor (A(2A)R), P2Y(1) receptor (P2Y(1)R) and P2Y(12) receptor (P2Y(12)R) are predominantly expressed on human platelets. The individual role of each of these receptors in platelet aggregation has been...
- The chromophore structure of the long-lived intermediate of the C128T channelrhodopsin-2 variant
[作者:Bruun, S; Naumann, H; Kuhlmann, U; Schulz, C; Stehfest, K; Hegemann, P; Hildebrandt, P,期刊:FEBS Letters, 页码:3998-4001 , 文章类型: Article,,卷期:2011年585-24]
- The photocycle of the light-activated channel, channelrhodopsin-2 C128T, has been studied by resonance Raman (RR) spectroscopy focussing on the intermediates P380 and P353 that constitute a side pathway in the recovery o...
- Human immunodeficiency virus-1 Rev protein activates hepatitis C virus gene expression by directly targeting the HCV 5 '-untranslated region
[作者:Qu, J; Yang, ZH; Zhang, Q; Liu, WY; Li, YX; Ding, Q; Liu, F; Liu, YL; Pan, ZS; He, BA; Zhu, Y; Wu, JG,期刊:FEBS Letters, 页码:4002-4009 , 文章类型: Article,,卷期:2011年585-24]
- Coinfection with human immunodeficiency virus-1 (HIV-1) and hepatitis C virus (HCV) accelerates hepatitis C disease progression; however, the mechanism underlying this effect is unknown. Here, we investigated the role of...
- Significance of uncoupling protein 3 in mitochondrial function upon mid- and long-term dietary high-fat exposure
[作者:Nabben, M; Hoeks, J; Moonen-Kornips, E; van Beurden, D; Briede, JJ; Hesselink, MKC; Glatz, JFC; Schrauwen, P,期刊:FEBS Letters, 页码:4010-4017 , 文章类型: Article,,卷期:2011年585-24]
- Uncoupling protein 3 (UCP3) may reduce mitochondrial ROS production, and thereby protect against mitochondrial dysfunction in skeletal muscle. UCP3 has been suggested to specifically fulfill this role under high-fat cond...
- Changes in cell migration of mesenchymal cells during osteogenic differentiation
[作者:Ichida, M; Yui, Y; Yoshioka, K; Tanaka, T; Wakamatsu, T; Yoshikawa, H; Itoh, K,期刊:FEBS Letters, 页码:4018-4024 , 文章类型: Article,,卷期:2011年585-24]
- We showed that the migration, morphology and adhesiveness of undifferentiated mesenchymal cells dramatically changed during osteogenic differentiation. The migration of these cells was transiently upregulated early in os...
- Purification and functional inactivation of the fission yeast MCM(MCM-BP) complex
[作者:Li, JJ; Schnick, J; Hayles, J; MacNeill, SA,期刊:FEBS Letters, 页码:3850-3855 , 文章类型: Article,,卷期:2011年585-24]
- The MCM (mini-chromosome maintenance) complex is the core of the eukaryotic replicative helicase and comprises six proteins, Mcm2-Mcm7. In humans, a variant form of the complex has Mcm2 replaced by the MCM-BP protein. Re...
- Gid9, a second RING finger protein contributes to the ubiquitin ligase activity of the Gid complex required for catabolite degradation
[作者:Braun, B; Pfirrmann, T; Menssen, R; Hofmann, K; Scheel, H; Wolf, DH,期刊:FEBS Letters, 页码:3856-3861 , 文章类型: Article,,卷期:2011年585-24]
- The two major antagonistic pathways of carbon metabolism in cells, glycolysis and gluconeogenesis, are tightly regulated. In the eukaryotic model organism Saccharomyces cerevisiae the switch from gluconeogenesis to glyco...
- Structural and functional characterization of Helicobacter pylori DsbG
[作者:Yoon, JY; Kim, J; Lee, SJ; Kim, HS; Im, HN; Yoon, HJ; Kim, KH; Kim, SJ; Han, BW; Suh, SW,期刊:FEBS Letters, 页码:3862-3867 , 文章类型: Article,,卷期:2011年585-24]
- Dsb proteins play important roles in bacterial pathogenicity. To better understand the role of Dsb proteins in Helicobacter pylori, we have structurally and functionally characterized H. pylori DsbG (HP0231). The monomer...
- Promiscuous interactions of human septins: The GTP binding domain of SEPT7 forms filaments within the crystal
[作者:Serrao, VHB; Alessandro, F; Caldas, VEA; Marcal, RL; Pereira, HD; Thiemann, OH; Garratt, RC,期刊:FEBS Letters, 页码:3868-3873 , 文章类型: Article,,卷期:2011年585-24]
- We describe the purification, crystallization and structure for the GTP-binding domain of human septin 7 (SEPT7G). We show that it forms filaments within the crystal lattice which employ both the G and NC interfaces, sim...
- Structural basis of gamma H2AX recognition by human PTIP BRCT5-BRCT6 domains in the DNA damage response pathway
[作者:Yan, W; Shao, ZH; Li, FD; Niu, LW; Shi, YY; Teng, MK; Li, X,期刊:FEBS Letters, 页码:3874-3879 , 文章类型: Article,,卷期:2011年585-24]
- Human Pax2 transactivation domain-interacting protein (hPTIP), containing six BRCT domains, is an essential protein required for the IR induced DDR process with an unclear role. Here we report that the tandem BRCT5-BRCT6...
|